Evidence for the occurrence of a novel pathway of benzoic acid metabolism involving the addition of a two carbon fragment

1981 ◽  
Vol 30 (13) ◽  
pp. 1879-1882 ◽  
Author(s):  
Mary Varwell Marsh ◽  
Andrew J. Hutt ◽  
John Caldwell ◽  
Robert L. Smith ◽  
Marion W. Horner ◽  
...  
Keyword(s):  
Benzoic Acid ◽  
Acid Metabolism ◽  
Carbon Fragment

scholarly journals A peroxisomal thioesterase plays auxiliary roles in plant β‐oxidative benzoic acid metabolism

2018 ◽  
Vol 93 (5) ◽  
pp. 905-916 ◽  
Author(s):  
Funmilayo Adebesin ◽  
Joshua R. Widhalm ◽  
Joseph H. Lynch ◽  
Rachel M. McCoy ◽  
Natalia Dudareva
Keyword(s):  
Benzoic Acid ◽  
Acid Metabolism

3-Acetamino-4-hydroxy-benzoesäure und 2-Acetaminophenol aus Pseudomonas-Kulturen [1] / 3-Acetamino-4-hydroxy Benzoic Acid and 2-Acetamino Phenol from Pseudomonas Cultures

1985 ◽  
Vol 40 (7-8) ◽  
pp. 474-476 ◽  
Author(s):  
S. Winkler ◽  
W. Neuenhaus ◽  
H. Budzikiewicz ◽  
H. Korth ◽  
G. Pulverer
Keyword(s):  
Benzoic Acid ◽  
Acid Metabolism ◽  
Pseudomonas Cepacia ◽  
Alternative Route ◽  
Chorismic Acid

Abstract Pseudomonas, Chorismic Acid Metabolism (Alternative Route), Phenazine Biosynthesis From Pseudomonas cepacia cultures 3-acetamino-4-hydroxy-benzoic acid has been isolated. This compound is of biogenetic interest as it suggests an alternative route in the chorismic acid metabolism initiated by an attack of an equivalent of NH3 at C-5 rather than at C-2 as usually observed. Implications on the phenazine biosynthesis have been discussed.

Biosynthesis of phenolic acids in tomato plants infected with Agrobacterium tumefaciens

1974 ◽  
Vol 52 (9) ◽  
pp. 2041-2047 ◽  
Author(s):  
Kailash C. Chadha ◽  
Stewart A. Brown
Keyword(s):  
Agrobacterium Tumefaciens ◽  
Benzoic Acid ◽  
Phenolic Acids ◽  
Cinnamic Acid ◽  
Acid Metabolism ◽  
Oxidation Products ◽  
Causative Organism ◽  
Coumaric Acid ◽  
Tomato Plants ◽  
Qualitative And Quantitative

Tomato plants 21 days old were inoculated with Agrobacterium tumefaciens, the causative organism of crown gall, and 72 h later [3-14C]cinnamic or [carboxyl-14C]benzoic acid was administered by wick-feeding to these and to uninfected control plants. After a further 48 h both groups were examined for incorporation of label into phenolic acids. The pattern of incorporation into bound phenolic acids of the controls was in accord with biosynthetic pathways previously demonstrated in normal plants, but qualitative and quantitative divergence from this pattern was observed in the bound phenolic acids of the infected plants. The data suggest interference by the pathogen with β-oxidation of at least two phenylpropanoid acids of the lignification pathway. In infected plants, lowered incorporation of 14C from cinnamic acid into phenylpropanoid acids of the lignification pathway and their β-oxidation products was accompanied by the appearance of labelled o-coumaric acid, consistent with some diversion of cinnamic acid metabolism toward ortho-hydroxylation. Incorporation of 14C from benzoic acid into gentisic and especially salicylic acid of infected plants was much lower than in the controls.

Benzoic acid metabolism reflects hepatic mitochondrial function in rats with long-term extrahepatic cholestasis

Hepatology ◽  
1997 ◽  
Vol 25 (2) ◽  
pp. 278-283 ◽  
Author(s):  
L Krähenbühl ◽  
J Reichen ◽  
C Talos ◽  
S Krähenbühl
Keyword(s):  
Benzoic Acid ◽  
Mitochondrial Function ◽  
Acid Metabolism ◽  
Extrahepatic Cholestasis

scholarly journals Degradation of phenylalanine and tyrosine by Sporobolomyces roseus

1968 ◽  
Vol 106 (2) ◽  
pp. 507-514 ◽  
Author(s):  
Keith Moore ◽  
P. V. Subba Rao ◽  
G. H. N. Towers
Keyword(s):  
Benzoic Acid ◽  
Caffeic Acid ◽  
Cinnamic Acid ◽  
Protocatechuic Acid ◽  
Acid Metabolism ◽  
Hydroxybenzoic Acid ◽  
Coumaric Acid ◽  
Tracer Studies ◽  
Lyase Activity ◽  
Sporobolomyces Roseus

Ammonia-lyase activity for l-phenylalanine, m-hydroxyphenylalanine and l-tyrosine was demonstrated in cell-free extracts of Sporobolomyces roseus. Cultures of this organism converted dl-[ring−14C]phenylalanine and l-[U−14C]tyrosine into the corresponding cinnamic acid. Tracer studies showed that these compounds were further metabolized to [14C]protocatechuic acid. Benzoic acid and p-hydroxybenzoic acid were intermediates in this pathway. Washed cells of the organism readily utilized cinnamic acid, p-coumaric acid, caffeic acid, benzoic acid and p-hydroxybenzoic acid. Protocatechuic acid was the terminal aromatic compound formed during the metabolism of these compounds. The cells of S. roseus were able to convert m-coumaric acid into m-hydroxybenzoic acid, but the latter compound, which accumulated in the medium, was not further metabolized. 4-Hydroxycoumarin was identified as the product of o-coumaric acid metabolism by this organism.

Effect ofPlasmodium berghei infection on benzoic acid metabolism in mice

1985 ◽  
Vol 41 (11) ◽  
pp. 1407-1409 ◽  
Author(s):  
T. S. Emudianughe ◽  
Q. D. Bickle ◽  
M. G. Taylor ◽  
B. Andrews
Keyword(s):  
Benzoic Acid ◽  
Acid Metabolism

scholarly journals Conjugation of benzoic acid in marsupials

1985 ◽  
Vol 33 (5) ◽  
pp. 693 ◽  
Author(s):  
Almah Bt. Awaluddin ◽  
Stuart McLean
Keyword(s):  
Benzoic Acid ◽  
Metabolic Pathway ◽  
Hippuric Acid ◽  
Urinary Metabolites ◽  
Carbon Fragment ◽  
Marsupial Species ◽  
Glycine Conjugate

The urinary metabolites of benzoic acid have been studied in seven marsupial species and the rat. Benzoic acid was excreted mainly as the glycine conjugate, hippuric acid, with smaller, though variable, amounts as benzoyl glucuronide. Thus the overall pattern of metabolism was similar to that found in most other mammals. All species formed significant amounts of a recently discovered metabolite of benzoic acid, 0-hydroxyphenylpropionic acid, suggesting that the metabolic pathway for its formation, involving the addition of a two-carbon fragment, may occur generally in other species.

Sign in / Sign up

Export Citation Format

Share Document