Characterization of the subpopulations of human peripheral blood B lymphocytes which react to Staphylococcus aureus Cowan I and T-cell help

1983 ◽  
Vol 78 (1) ◽  
pp. 130-143 ◽  
Author(s):  
Dorothy M. Wrigley ◽  
Yong Sung Choi
1981 ◽  
Vol 154 (3) ◽  
pp. 778-790 ◽  
Author(s):  
E L Morgan ◽  
W O Weigle

Fc fragments derived from human immunoglobulin were found to be capable of inducing both a proliferative and polyclonal antibody response in human peripheral blood lymphocyte cultures. The cell population proliferating in response to Fc fragments belongs to the B cell lineage. Expression of polyclonal antibody formation requires the presence of both adherent monocytes and T cells. The role of the monocyte is to enzymatically cleave the Fc fragment into 19,000 mol wt Fc subfragments that are then able to induce polyclonal antibody secretion. Stimulation of polyclonal antibody production by Fc subfragments occurs in the absence of adherent monocytes but still requires the presence of T cells.


BMC Genomics ◽  
2013 ◽  
Vol 14 (1) ◽  
pp. 804 ◽  
Author(s):  
Haiyan Lei ◽  
Tianwei Li ◽  
Guo-Chiuan Hung ◽  
Bingjie Li ◽  
Shien Tsai ◽  
...  

1989 ◽  
Vol 19 (7) ◽  
pp. 1183-1188 ◽  
Author(s):  
Silvano Ferrini ◽  
Daniela Zarcone ◽  
Maurizio Viale ◽  
Giannamaria Cerruti ◽  
Romano Millo ◽  
...  

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