scholarly journals Identification and characterization of EBV genomes in spontaneously immortalized human peripheral blood B lymphocytes by NGS technology

BMC Genomics ◽  
2013 ◽  
Vol 14 (1) ◽  
pp. 804 ◽  
Author(s):  
Haiyan Lei ◽  
Tianwei Li ◽  
Guo-Chiuan Hung ◽  
Bingjie Li ◽  
Shien Tsai ◽  
...  
Keyword(s):  
B Lymphocytes ◽  
Peripheral Blood ◽  
Human Peripheral Blood ◽  
Identification And Characterization

scholarly journals Polyclonal activation of human B lymphocytes by Fc fragments. I. Characterization of the cellular requirements for Fc fragment-mediated polyclonal antibody secretion by human peripheral blood B lymphocytes.

1981 ◽  
Vol 154 (3) ◽  
pp. 778-790 ◽  
Author(s):  
E L Morgan ◽  
W O Weigle
Keyword(s):  
T Cells ◽  
B Lymphocytes ◽  
Polyclonal Antibody ◽  
Peripheral Blood ◽  
Human Peripheral Blood ◽  
Cell Lineage ◽  
Fc Fragment ◽  
Antibody Secretion

Fc fragments derived from human immunoglobulin were found to be capable of inducing both a proliferative and polyclonal antibody response in human peripheral blood lymphocyte cultures. The cell population proliferating in response to Fc fragments belongs to the B cell lineage. Expression of polyclonal antibody formation requires the presence of both adherent monocytes and T cells. The role of the monocyte is to enzymatically cleave the Fc fragment into 19,000 mol wt Fc subfragments that are then able to induce polyclonal antibody secretion. Stimulation of polyclonal antibody production by Fc subfragments occurs in the absence of adherent monocytes but still requires the presence of T cells.

Characterization of amine oxidase activities in macrophages from human peripheral blood

1995 ◽  
Vol 73 (5-6) ◽  
pp. 275-281 ◽  
Author(s):  
Nikolaus Seiler ◽  
Jacques-Philippe Moulinoux ◽  
Rene Havouis ◽  
Louis Toujas
Keyword(s):  
Hydrogen Peroxide ◽  
Monoamine Oxidase ◽  
Peripheral Blood ◽  
Diamine Oxidase ◽  
Human Peripheral Blood ◽  
Polyamine Oxidase ◽  
Regulatory Function ◽  
Amine Oxidases ◽  
Identification And Characterization

A sensitive assay for the determination of hydrogen peroxide formation and a method for the identification and characterization of amine oxidases in cells and other oxidase sources of limited accessibility are described. The enzymes are characterized by substrate and inhibitor patterns. The method was applied to the identification and characterization of polyamine oxidizing enzymes in macrophages from human peripheral blood. The major oxidase activity in these cells was found to be a tissue-type polyamine oxidase, but with distinct characteristics. Diamine oxidase and monoamine oxidase activities were also detected in homogenates of macrophages. Since the formation of toxic products by a releasable polyamine oxidase is supposed to be an integral part of a regulatory function of macrophages, we consider our work as a basis for the elucidation of this function.Key words: macrophages, amine oxidases, polyamine oxidase, diamine oxidase, monoamine oxidase, hydrogen peroxide, fluorimetry.

scholarly journals HIV-1 Tat protein induces DNA damage in human peripheral blood B-lymphocytes via mitochondrial ROS production

Redox Biology ◽  
2018 ◽  
Vol 15 ◽  
pp. 97-108 ◽  
Author(s):  
Rawan El-Amine ◽  
Diego Germini ◽  
Vlada V. Zakharova ◽  
Tatyana Tsfasman ◽  
Eugene V. Sheval ◽  
...  
Keyword(s):  
Dna Damage ◽  
B Lymphocytes ◽  
Peripheral Blood ◽  
Human Peripheral Blood ◽  
Ros Production ◽  
Tat Protein ◽  
Mitochondrial Ros ◽  
Hiv 1
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