Influence of free fatty acid anion on the binding of warfarin to cytoplasmic proteins from rat liver

1980 ◽  
Vol 29 (1) ◽  
pp. 85-94 ◽  
Author(s):  
Louise Charest-Boule ◽  
Saroj Chakrabarti ◽  
Jules Brodeur
Keyword(s):  
Fatty Acid ◽  
Free Fatty Acid ◽  
Rat Liver ◽  
Acid Anion ◽  
Cytoplasmic Proteins ◽  
Fatty Acid Anion

scholarly journals Two fatty acid anion-based ionic liquids - part I: Physicochemical properties and tribological behavior as neat lubricants

2020 ◽  
Vol 305 ◽  
pp. 112827 ◽  
Author(s):  
M. Sernaglia ◽  
D. Blanco ◽  
A. Hernández Battez ◽  
J.L. Viesca ◽  
R. González ◽  
...  
Keyword(s):  
Ionic Liquids ◽  
Fatty Acid ◽  
Physicochemical Properties ◽  
Tribological Behavior ◽  
Acid Anion ◽  
Fatty Acid Anion

Free fatty acid level in rat liver after ingestion of polyunsaturated fatty acids

Lipids ◽  
1969 ◽  
Vol 4 (1) ◽  
pp. 77-79 ◽  
Author(s):  
Akira Yamamoto ◽  
Masahiro Isozaki ◽  
Takeshi Ishibe ◽  
Mitsuo Nishikawa
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Free Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Rat Liver ◽  
Acid Level ◽  
Free Fatty Acid Level ◽  
Fatty Acid Level

scholarly journals Natural and Azido Fatty Acids Inhibit Phosphate Transport and Activate Fatty Acid Anion Uniport Mediated by the Mitochondrial Phosphate Carrier

2000 ◽  
Vol 276 (7) ◽  
pp. 4683-4691 ◽  
Author(s):  
Hana Engstová ◽  
Markéta Z̆ác̆ková ◽  
Michal Růz̆ic̆ka ◽  
Andrea Meinhardt ◽  
Jan Hanuš ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Phosphate Transport ◽  
Acid Anion ◽  
Fatty Acid Anion ◽  
Phosphate Carrier ◽  
Anion Uniport

Uncoupling activity of endogenous free fatty acids in rat liver mitochondria

1978 ◽  
Vol 56 (2) ◽  
pp. 111-116 ◽  
Author(s):  
Samuel H. P. Chan ◽  
Edward Higgins Jr.
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Free Fatty Acid ◽  
Free Fatty Acids ◽  
Rat Liver ◽  
Respiratory Control ◽  
Aging Effect ◽  
Liver Mitochondria ◽  
Rat Liver Mitochondria

Changes in the respiratory control index (RCI) and ADP:O ratio were found to be related to alterations in the free fatty acids levels of rat liver mitochondria aging in 0.25 M sucrose–Tris buffer at 0 °C. Free fatty acid levels increased with time after isolation of mitochondria while a concomitant decrease in the RCI and ADP:O ratio occurred. The changes in free fatty acid levels corresponded with the reported increasing levels of phospholipase A activity in aged mitochondrial preparations. Washing these mitochondria with sucrose buffer containing 1% defatted bovine serum albumin (BSA) counteracted the aging effect on the RCI (e.g., 2.5 to 3.5) and reduced the free fatty acid levels (e.g., 50 to 16 nmol/mg protein). This reversible phenomenon could be repeated several times during the in vitro aging at 0 °C. Use of 125I-iodinated BSA showed that approximately 5 μg BSA/mg mitochondria was adsorbed by the mitochondrial membranes during washing. These results indicate a direct correlation between the level of endogenous fatty acids and the uncoupling of mitochondrial oxidative phosphorylation. The mechanism of counteracting the aging effect by BSA involves the removal of some of the free fatty acids.

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