Baclofen withdrawal and neuropsychiatric symptoms: A case report and review of other case literature

1986 ◽  
Vol 27 (4) ◽  
pp. 396-400 ◽  
Author(s):  
Mary E. Swigar ◽  
Malcolm B. Bowers
Keyword(s):  
Case Report ◽  
Neuropsychiatric Symptoms ◽  
Baclofen Withdrawal

Neuropsychiatric Derangement by Polycythemia Vera: A Case Report of an Unexpected Disease Presentation and Review of the Literature

2021 ◽  
pp. 1-6
Author(s):  
Heleen De Lil ◽  
Michelle van Beek ◽  
Alexandra Herbers ◽  
Ellen van der Holst ◽  
Karen Keijsers
Keyword(s):  
Case Report ◽  
Chronic Disease ◽  
Cerebral Infarction ◽  
Polycythemia Vera ◽  
Neuropsychiatric Symptoms ◽  
Unusual Presentation ◽  
Review Of The Literature ◽  
Remarkable Recovery ◽  
Visual Complaints ◽  
Underlying Pathophysiology

Cerebral infarction as well as other thromboses, headaches, and visual complaints are well-known symptoms of polycythemia vera. However, chorea and neuropsychiatric disturbances are less recognized consequences of this chronic disease. Whereas chorea is a rare but acknowledged symptom of polycythemia vera, neuropsychiatric symptoms have only sporadically been reported. We depict 2 patients with an unusual presentation of polycythemia vera. Our first patient presented with right-sided hemiballism and psychosis, and the second patient had a long diagnostic trajectory of unexplained chorea. In both cases diagnosis of JAK2 positive polycythemia vera was established, and in both cases remarkable recovery occurred after the initiation of phlebotomies. The underlying pathophysiology of these symptoms has not been clearly elucidated. Because of the unfamiliarity of the link between especially neuropsychiatric symptoms and polycythemia, current reported numbers are probably an underestimation. Benefit of treatment appears to be large. We seek to create more awareness among physicians about this phenomenon.

Not a Usual Suspect; Rabeprazole Therapy Presenting as a Severe Neuropsychiatric Illness: Case Report

2003 ◽  
Vol 33 (3) ◽  
pp. 311-315 ◽  
Author(s):  
Christopher A. Alfonzo ◽  
William V. Bobo ◽  
Myron D. Almond
Keyword(s):  
Psychological Distress ◽  
Case Report ◽  
Neuropsychiatric Symptoms ◽  
Tolerability Profile ◽  
Side Effect Profile ◽  
Symptom Presentation ◽  
Healthcare Resources ◽  
Usual Suspect ◽  
Neuropsychiatric Illness ◽  
Progressive Course

We report the case of a patient who, as a result of exposure to the proton pump inhibitor rabeprazole, developed a severe and disabling admixture of neuropsychiatric symptoms. Because of its widely appreciated placebo-like side effect profile, rabeprazole was never suspected as being the cause of his symptoms. Instead, a somatoform spectrum disorder was assigned based on the patient's atypical symptom presentation, progressive course, subjective psychological distress, intemperate consumption of healthcare resources over a relatively brief period of time and lack of any medical explanation for his symptoms at that time, despite exhaustive laboratory and radiologic work-ups. This case report reinforces the notion that even a medication such as rabeprazole, with an established safety and tolerability profile, may be associated with side effects severe enough to mimic disabling neuropsychiatric illness.

scholarly journals Neuropsychological profile of a male psychiatric patient with a Morgagni-Stewart-Morel syndrome

2014 ◽  
Vol 27 (1) ◽  
pp. 60-64 ◽  
Author(s):  
Aksel Hansen ◽  
Liliana Engelhardt ◽  
Wolfgang Pleschutznig ◽  
Gerhard Dammann ◽  
Stephanie Vietze
Keyword(s):  
Case Report ◽  
Psychiatric Patient ◽  
Neuropsychological Tests ◽  
Psychiatric Symptoms ◽  
Case Reports ◽  
Neuropsychiatric Symptoms ◽  
Pain Syndrome ◽  
Admission Diagnosis ◽  
Neuropsychological Profile ◽  
Definition Of

In 1765 Giovanni Morgagni described a syndrome consisting of hyperostosis frontalis interna (HFI), obesity and hirsutism. In 1928 Stewart and in 1930 Morel added neuropsychiatric symptoms, e.g. depression and dementia, which led to the definition of the Morgagni-Stewart-Morel Syndrome (MSM). Although mostly women were characterized in literature no gender specifity is demanded. This case report presents the rare case of a 66 year old male psychiatric patient with Morgagni-Stewart-Morel Syndrome. The patient complained of loss of concentration and difficulties with activities of daily living. Admission diagnosis was an opioid misuse on the basis of a chronic pain syndrome. In this case report we are describing clinical features, the patient history and technical (MRI) and neuropsychological tests. Although severe psychiatric symptoms and neuropsychological deficits are commonly seen in these patients, our patient showed only mild symptoms. This case reports shows the possibility of a male patient with MSM. If MSM is a separate entity or just an epiphenomena of hormone dysregulation should be investigated in further studies.

Intrathecal baclofen withdrawal: a case report and review of the literature

2002 ◽  
Vol 18 (9-10) ◽  
pp. 522-525 ◽  
Author(s):  
Tord D. Alden ◽  
Richard A. Lytle ◽  
T. Park ◽  
Michael J. Noetzel ◽  
Jeffrey G. Ojemann
Keyword(s):  
Case Report ◽  
Intrathecal Baclofen ◽  
Review Of The Literature ◽  
Baclofen Withdrawal

Dementia in Parkinson's disease: Case report

2011 ◽  
Vol 26 (S2) ◽  
pp. 846-846
Author(s):  
S.G. Oliveira ◽  
S.M. Pereira ◽  
J. Mendes
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Case Report ◽  
Psychiatric Hospitalization ◽  
Psychological Symptoms ◽  
Neuropsychiatric Symptoms ◽  
Diagnostic Testing ◽  
Visual Hallucinations ◽  
Psychomotor Agitation ◽  
Disease Case

IntroductionParkinson's disease (PD) dementia is a rapidly growing global health problem. Dementia in PD is often accompanied with neuropsychiatric manifestations, such as depression, insomnia, visual hallucinations and psychomotor agitation, which need psychiatric attention.ObjectivesThe authors’ aim is to report a case of a 76-year-old female suffering from PD who was admitted to the psychiatric yard exhibiting neuropsychiatric symptoms. A literature's review about PD dementia was also made.Case reportPatient had one psychiatric hospitalization at age 41, due to depressive symptoms. PD diagnose was made at age 65 and initially responded well to levodopa. Over the subsequent years, motor fluctuations and dyskinesias as well as autonomic, cognitive and psychological symptoms gradually developed. At 75 years, patient's family stated that she had been more forgetful, impulsive, showing signs of anxiety and dysphoria. She was hospitalized exhibiting psychomotor agitation, disorientation, insomnia and mainly nocturnal visual hallucinations with persons. Diagnostic testing included: cranial tomography which showed mild generalized atrophy but no other structural cause of her symptoms; laboratory tests with B12, folic acid, thyroid function; syphilis detection test and examinations of serum and urine were normal. The MMSE scored 19. Attention deficits and constructional apraxia were present in clock drawing test. Treatment was initiated with memantine and a low dose of quetiapine. She was discharged after 20 days with improvement of neuropsychiatric symptoms.ConclusionsEarly diagnosis and treatment of dementia in PD may prevent psychiatric hospitalization and avoid patient's and family's distress.

scholarly journals Ekbom Syndrome associated with Lewy Body Dementia: A case report

2020 ◽  
Vol 14 (1) ◽  
pp. 83-87
Author(s):  
Felippe José Pontes de Mendonça ◽  
Ivan Abdalla Teixeira ◽  
Valeska Marinho
Keyword(s):  
Case Report ◽  
Lewy Body ◽  
Psychiatric Symptoms ◽  
Neuropsychiatric Symptoms ◽  
Correct Diagnosis ◽  
Lewy Body Dementia ◽  
Rare Condition ◽  
Adequate Treatment ◽  
Thought Disorders ◽  
Ekbom Syndrome

ABSTRACT Ekbom Syndrome, also known as parasitosis delusion or psychogenic parasitosis, is a rare condition in which patients present with a fixed belief of being infested by parasites, vermin or small insects, along with tactile hallucinations (such as pruritus or sensations of the parasites crawling over or under the skin). The syndrome may occur idiopathically or be associated with other medical conditions and drug use. This case report describes the occurrence of Ekbom syndrome in a patient diagnosed with Lewy Body Dementia (LBD), a neurodegenerative disease that commonly presents with sensory perception and thought disorders and other neuropsychiatric symptoms. Although visual hallucination is considered a core diagnostic criterion, other modalities of psychiatric symptoms can also occur posing a further challenge for correct diagnosis. Proper recognition allows early diagnosis and adequate treatment, preventing hazardous antipsychotic use in these patients.

scholarly journals Frontotemporal dementia and neurocysticercosis: a case report

2012 ◽  
Vol 6 (1) ◽  
pp. 64-69
Author(s):  
Corina Satler ◽  
Elza Santos Maestro ◽  
Carlos Tomaz
Keyword(s):  
Case Report ◽  
Cognitive Functioning ◽  
Frontotemporal Dementia ◽  
Neuropsychiatric Symptoms ◽  
Verbal Communication ◽  
Behavioral Changes ◽  
Nonfluent Aphasia ◽  
Progressive Deterioration ◽  
History Of ◽  
Progressive Nonfluent Aphasia

ABSTRACT We report a case of a 67-year-old woman with frontotemporal dementia (FTD) and a history of neurocysticercosis. After her retirement she showed progressive behavioral changes and neuropsychiatric symptoms with relative preservation of cognitive functioning. During the next three years, the patient manifested progressive deterioration of verbal communication gradually evolving to mutism, a hallmark of cases of progressive nonfluent aphasia.

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