scholarly journals Neuropsychological profile of a male psychiatric patient with a Morgagni-Stewart-Morel syndrome

2014 ◽  
Vol 27 (1) ◽  
pp. 60-64 ◽  
Author(s):  
Aksel Hansen ◽  
Liliana Engelhardt ◽  
Wolfgang Pleschutznig ◽  
Gerhard Dammann ◽  
Stephanie Vietze
Keyword(s):  
Case Report ◽  
Psychiatric Patient ◽  
Neuropsychological Tests ◽  
Psychiatric Symptoms ◽  
Case Reports ◽  
Neuropsychiatric Symptoms ◽  
Pain Syndrome ◽  
Admission Diagnosis ◽  
Neuropsychological Profile ◽  
Definition Of

In 1765 Giovanni Morgagni described a syndrome consisting of hyperostosis frontalis interna (HFI), obesity and hirsutism. In 1928 Stewart and in 1930 Morel added neuropsychiatric symptoms, e.g. depression and dementia, which led to the definition of the Morgagni-Stewart-Morel Syndrome (MSM). Although mostly women were characterized in literature no gender specifity is demanded. This case report presents the rare case of a 66 year old male psychiatric patient with Morgagni-Stewart-Morel Syndrome. The patient complained of loss of concentration and difficulties with activities of daily living. Admission diagnosis was an opioid misuse on the basis of a chronic pain syndrome. In this case report we are describing clinical features, the patient history and technical (MRI) and neuropsychological tests. Although severe psychiatric symptoms and neuropsychological deficits are commonly seen in these patients, our patient showed only mild symptoms. This case reports shows the possibility of a male patient with MSM. If MSM is a separate entity or just an epiphenomena of hormone dysregulation should be investigated in further studies.

scholarly journals Ekbom Syndrome associated with Lewy Body Dementia: A case report

2020 ◽  
Vol 14 (1) ◽  
pp. 83-87
Author(s):  
Felippe José Pontes de Mendonça ◽  
Ivan Abdalla Teixeira ◽  
Valeska Marinho
Keyword(s):  
Case Report ◽  
Lewy Body ◽  
Psychiatric Symptoms ◽  
Neuropsychiatric Symptoms ◽  
Correct Diagnosis ◽  
Lewy Body Dementia ◽  
Rare Condition ◽  
Adequate Treatment ◽  
Thought Disorders ◽  
Ekbom Syndrome

ABSTRACT Ekbom Syndrome, also known as parasitosis delusion or psychogenic parasitosis, is a rare condition in which patients present with a fixed belief of being infested by parasites, vermin or small insects, along with tactile hallucinations (such as pruritus or sensations of the parasites crawling over or under the skin). The syndrome may occur idiopathically or be associated with other medical conditions and drug use. This case report describes the occurrence of Ekbom syndrome in a patient diagnosed with Lewy Body Dementia (LBD), a neurodegenerative disease that commonly presents with sensory perception and thought disorders and other neuropsychiatric symptoms. Although visual hallucination is considered a core diagnostic criterion, other modalities of psychiatric symptoms can also occur posing a further challenge for correct diagnosis. Proper recognition allows early diagnosis and adequate treatment, preventing hazardous antipsychotic use in these patients.

Adrenocortical Crisis Triggered by Levothyroxine in an Unrecognized Autoimmune Polyglandular Syndrome Type-2: A Case Report with Review of the Literature.

2020 ◽  
Vol 15 ◽  
Author(s):  
Dhruvkumar M. Patel ◽  
Jayanti K. Gurumikhani ◽  
Mukund Kumar Patel ◽  
Maitri M. Patel ◽  
Suyog Y Patel ◽  
...  
Keyword(s):  
Case Report ◽  
Case Reports ◽  
Neuropsychiatric Symptoms ◽  
Hypovolemic Shock ◽  
Addison’S Disease ◽  
Addison's Disease ◽  
Thyroid Function Tests ◽  
Thyroid Disorder ◽  
Review Of The Literature ◽  
Autoimmune Hypothyroidism

Background: Autoimmune polyglandular syndrometype-2 (APS-2) is an uncommon endocrine disorder of Addison's disease with an autoimmune thyroid disorder and/or type 1 diabetes mellitus. The diagnosis is more challenging when a patient presents with nonspecific neuropsychiatric features with hypothyroidism in the setting of unrecognized Addison's disease. Case report: We report a case of subclinical autoimmune hypothyroidism presented with nonspecific neuropsychiatric symptoms precipitated by stress. Despite levothyroxine treatment, her symptoms deteriorated and she was admitted with persistent vomiting and hypovolemic shock. Clinical features and laboratory parameters were suggestive of underlying adrenocortical insufficiency. Pre-existing autoimmune hypothyroidism combined with Addison's disease confirmed the diagnosis of unrecognized APS-2. She remarkably improved and her thyroid function tests also normalized with the treatment of corticosteroids only. Review of the literature: We identified only five published case reports of our title by searching the database. Neufeld and Betterle have reported their data of APS-2 and concluded that a full-blown clinical picture of two or more components of the syndrome is like the tip of the iceberg. Conclusion : The patients of one major component of APS-2 should be screened for other components of the disease to pick up latent cases. Addison's disease should be ruled out in patients of hypothyroidism who are intolerant to levothyroxine.

scholarly journals Acute Psychosis in a Child with Severe Dengue

2018 ◽  
Vol 37 (3) ◽  
pp. 273-275
Author(s):  
Ruchika Bhatnagar ◽  
Premlochan Prasad
Keyword(s):  
Psychiatric Symptoms ◽  
Case Reports ◽  
Neuropsychiatric Symptoms ◽  
Adult Population ◽  
Febrile Illness ◽  
Recovery Phase ◽  
Severe Dengue ◽  
Age Group ◽  
Acute Psychosis ◽  
Pediatric Age Group

Dengue fever is emerging as an important cause of acute febrile illness with neuropsychiatric symptoms in adult population especially in endemic areas. Numerous case reports and review articles have already been published in past emphasizing on neurological manifestations in dengue but sufficient data on psychiatric symptoms in pediatric age group is still lacking. Acute psychosis in recovery phase of severe dengue is an uncommon phenomenon, thus rarely reported.

De novo genesis of neuropsychiatric symptoms in Mild Cognitive Impairment (MCI)

2004 ◽  
Vol 16 (1) ◽  
pp. 51-60 ◽  
Author(s):  
Yonas E. Geda ◽  
Glenn E. Smith ◽  
David S. Knopman ◽  
Bradley F. Boeve ◽  
Eric G. Tangalos ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Rating Scale ◽  
De Novo ◽  
Psychiatric Symptoms ◽  
Neuropsychiatric Symptoms ◽  
Cross Sectional ◽  
Neuropsychological Profile ◽  
Pair Wise Comparison ◽  
Normal Controls

Background: There is inadequate information regarding the neuropsychiatric aspect of Mild Cognitive Impairment (MCI).Objective: To determine the neuropsychiatric profile of MCI, and compare this with normal controls and patients with mild Alzheimer's Disease (AD).Design: Cross-sectional assessment of psychiatric symptoms in subjects that are enrolled in Mayo Clinic's longitudinal study of normal aging, MCI and dementia.Methods and Participants: The Neuropsychiatric Inventory (NPI) was administered to normal control subjects, MCI subjects and patients with early AD. Individual NPI domain scores and total NPI scores were compared among the three groups after controlling for age, educational status, Dementia Rating Scale (DRS) and Mini-Mental State Examination (MMSE) scores. Statistical analysis was performed by utilizing ANOVA, χ2 and Fisher's exact test.Results: Data were analyzed on 514 normal controls, 54 MCI subjects, and 87 subjects with mild AD (CDR of 0.5 or 1); females consisted of 60.3%, 53.7% and 57.5%; and, the average ages (SD) were 77.8 (1.95), 79 (4.6), 80.5 (14.6) respectively. ANOVA pair-wise comparison revealed that both MMSE and DRS differences among the three groups were significantly different at (p=0.05). The total NPI scores were significantly different (p=0.0001, F=107.93) among the three groups using ANOVA. Pair-wise comparison of individual behavioral domain of NPI showed statistically significant differences between MCI and normals; and MCI and AD (p=0.001). Group differences on NPI remained after controlling for age and education at p=0.0375 and p=0.0050 respectively.Conclusion: The neuropsychiatric pattern is reminiscent of the clinical, neuroimaging and neuropsychological profile of MCI. It gives further credence to the view that MCI is indeed the gray zone, with overlap on both ends of the pole.

scholarly journals Management of Depression Associated with HIV/AIDS and Antiretrovial Therapy

2006 ◽  
Vol 17 (suppl d) ◽  
pp. 5D-9D
Author(s):  
Mark Halman
Keyword(s):  
Major Depression ◽  
Psychiatric Symptoms ◽  
Social Withdrawal ◽  
Case Reports ◽  
Meta Analysis ◽  
Neuropsychiatric Symptoms ◽  
Medical Illness ◽  
Open Label ◽  
Antiretroviral Adherence ◽  
Hiv Aids

Depressed mood is a common psychiatric complaint in persons with HIV/AIDS, with a meta-analysis indicating that the rates of depression within this group may be as high as double that of the general population. Depression may result from a biological diathesis to mood disorders, a physiological reaction to a medical illness or its treatment, and/or a psychological reaction to challenging life circumstances. Associated symptoms include sleep, energy and appetite disturbances; social withdrawal; diminished capacity to experience pleasure; diminished concentration; feelings of worthlessness, shame and guilt; and recurrent thoughts of death, including suicidal ideation. The emotionally and physically painful state of major depression is associated with decreased antiretroviral adherence and poorer HIV/AIDS disease outcomes. Neuropsychiatric symptoms have been reported with several of the medications taken by patients with HIV/AIDS, including lamivudine, zidovudine, interferon and, most notably, efavirenz. However, data from several sources demonstrate that neuropsychiatric symptoms associated with efavirenz use are generally transient, with onset early after treatment initiation, peaking after one week and decreasing over the first one to four months of treatment. Recent comparative studies have not found elevated incident rates of major depression in patients treated with efavirenz, but they have confirmed the typical neuropsychiatric symptoms reported in earlier open-label studies and case reports. Becoming skilled in the management of depression and psychiatric symptoms is integral to the provision of comprehensive care for patients with HIV/AIDS.

scholarly journals Brief psychotic disorder occurring after Covid-19 in a patient with no history of psychiatric diseases - a case report

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Julita Poleszak-Szabat ◽  
Małgorzata Romaniuk-Suswał ◽  
Paweł Krukow
Keyword(s):  
Case Report ◽  
Psychotic Disorder ◽  
Psychiatric Symptoms ◽  
Neuropsychiatric Symptoms ◽  
Psychiatric Diseases ◽  
Brief Psychotic Disorder ◽  
History Of ◽  
The Central Nervous System ◽  
Isolation Ward

Abstract Introduction: Although the typical symptoms of SARS-CoV-2 infection are respiratory symptoms, it has been shown that the virus can also attack the central nervous system (CNS) causing neurological and psychiatric symptoms. Aim: The aim of the study was to present a case of a 52-year-old woman, previously untreated for psychiatric diseases, who developed brief psychotic disorder occurring after Covid-19 infection. Case report: A patient in the biological treatment of asthma, came for a follow-up visit, during which the doctor diagnosed psychopathological symptoms in the form of delusions, never previously observed. The interview showed that the patient was discharged from the Isolation ward 10 days before, where she was hospitalized because of SARS-CoV-2 infection. Discussion: There are several theories regarding the mechanisms of pathogenesis of neuropsychiatric symptoms in the course of Covid-19 infection. Much space in the literature is devoted to pathological immune responses. One of the reasons for the development of delusions in the described patient could therefore be the acute phase of the inflammatory reaction in the course of SARS-CoV-2 infection.

scholarly journals Comparing the Neuropsychiatric Profile of Patients with Alzheimer Disease Who Present Spared versus Impaired Executive Functioning

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Ezequiel Gleichgerrcht ◽  
Anabel Chade ◽  
Teresa Torralva ◽  
María Roca ◽  
Facundo Manes
Keyword(s):  
Alzheimer Disease ◽  
Executive Functioning ◽  
Neuropsychological Tests ◽  
Motor Behavior ◽  
Psychiatric Symptoms ◽  
Neuropsychiatric Symptoms ◽  
Significant Difference ◽  
Repetitive Motor ◽  
Shed Light

Background. A “dysexecutive” group of patients with Alzheimer disease (AD) has been previously identified, and these patients have been found to present higher frequency of psychiatric symptoms and more pronounced functional impact. This study aimed at evaluating the frequency of neuropsychiatric symptoms in patients with early AD who present with impaired executive functioning.Methods. Thirty patients with early AD diagnosis were divided into a spared (SEF) and an impaired (IEF) executive functioning group according to their performance scores on neuropsychological tests. Their closest relatives or caregivers completed the Cambridge behavioral inventory (CBI), which assesses behavioral symptoms grouped into 13 categories.Results. A significant difference was exclusively found between SEF and IEF in terms of the frequency of stereotypies and repetitive motor behavior (U=60.5,P=.024).Conclusions. The presence of stereotypies could be associated with a dysexecutive profile in AD patients. These results shed light on the role of frontal circuitry in the expression of motor symptoms in AD and prompt for further research that will contribute to the differential diagnosis both of different subtypes of AD and other types of dementia.

Neuropsychiatric Side-Effects of Lidocaine: Examples from the Treatment of Headache and a Review

Cephalalgia ◽  
2009 ◽  
Vol 29 (5) ◽  
pp. 496-508 ◽  
Author(s):  
R Gil-Gouveia ◽  
PJ Goadsby
Keyword(s):  
Side Effects ◽  
Clinical Presentation ◽  
Psychiatric Symptoms ◽  
Case Reports ◽  
Neuropsychiatric Symptoms ◽  
Alternative Therapy ◽  
Intravenous Lidocaine ◽  
Refractory Headache ◽  
Neuropsychiatric Toxicity ◽  
Neuropsychiatric Side Effects

Lidocaine has been used in treatment of patients with refractory headache. Personal observations of neuropsychiatric toxicity in these patients led us to review our cases and the literature systematically for lidocaine side-effects, especially neuropsychiatric symptoms. In our series of 20 patients, side-effects were observed in all, the most frequent being neuropsychiatric (75%) and cardiological (50%). When reviewing published series on intravenous lidocaine use, reports of side-effects range from 0 to 100%, with neuropsychiatric symptoms being reported in 1.8–100%. Thirty-six case reports of lidocaine-induced psychiatric symptoms were also analysed. Psychiatric symptoms of toxicity were similar in most patients, despite their differing ages, pathologies, co-therapies and lidocaine dosages. In conclusion, lidocaine neuropsychiatric toxicity has a well-recognized stereotypical clinical presentation that is probably unrecognized in headache series. As lidocaine represents an emerging alternative therapy in headache, particularly in short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing, clinicians and patients should be aware of the extent of this problem.

scholarly journals Oseltamivir-induced behavioral changes in a female Lebanese adolescent: a case report of a usual drug with unusual side effect

2020 ◽  
pp. FSO602 ◽  
Author(s):  
Rabih Fares ◽  
Antoine Zgheib ◽  
Rabih Hallit ◽  
Souheil Hallit
Keyword(s):  
Abdominal Pain ◽  
Case Report ◽  
Literature Review ◽  
Side Effect ◽  
Case Reports ◽  
Neuropsychiatric Symptoms ◽  
Female Adolescent ◽  
Behavioral Changes ◽  
Abnormal Behavior ◽  
Behavioral Activities

Neuropsychiatric symptoms, including abnormal behavior, after oseltamivir use among influenza patients have been of concern. In recent years, many case reports of neuropsychiatric events during or after oseltamivir treatment were reported; however, literature review revealed no such cases in Lebanon. Oseltamivir is the most widely prescribed medication against influenza and is generally well tolerated, causing random gastrointestinal disturbances, including nausea, vomiting, diarrhea and abdominal pain. However, in rare instances, it has been reported to stimulate behavioral activities in adolescents. We report herein a case of an oseltamivir-related neuropsychiatric event in a female adolescent in Lebanon, which resolved 2 days after stopping the drug.

A review about comorbidity between obsessive-compulsive symptoms and huntintong disease and a case report

2017 ◽  
Vol 41 (S1) ◽  
pp. S702-S703
Author(s):  
L. Sánchez Blanco ◽  
M. Juncal Ruíz ◽  
G. Pardo de Santayana Jenaro ◽  
M. Goméz Revuelta ◽  
R. Landera Rodríguez ◽  
...  
Keyword(s):  
Case Report ◽  
Basal Ganglia ◽  
Psychiatric Symptoms ◽  
Therapeutic Option ◽  
Neuropsychiatric Symptoms ◽  
Previous History ◽  
Depressive Mood ◽  
Obsessive Compulsive ◽  
Obsessive Compulsive Symptoms ◽  
Compulsive Disorder

IntroductionThe concept of obsessive-compulsive disorder (OCD) as a disorder that affects the basal ganglia arising to the phenomenological similarities found between idiopathic OCD and other conditions associated with basal ganglia disease such as Huntington's disease (HD) and Sydenham's chorea. Huntintong's disease is characterized by cognitive, motor and neuropsychiatric symptoms.AimsA review of articles published from 1989 to 2016 in Pub-Med and UpToDate about relationship between HD and obsessive-compulsive symptoms.MethodsCase report of a 56-year-old male who was admitted at the acute unit of psychiatry with obsessive-compulsive symptoms marked by hypochondriac obsessive thoughts. He also had cleaning rituals in relation with meals and we observed an important functional impairment and depressive mood. No previous history except family chorea without cognitive impairment in study by neurology department.ResultsAffective disorders are the most common psychiatric disorders in HD. Less frequently it can be found other psychiatric symptoms as obsessive-compulsive behaviour with prevalences between 10% to 52%. Psychiatric symptoms do not correlate with duration of disease or presence of dementia or motor symptoms.ConclusionsIt is necessary to complete the study of the patient to provide a more appropriate therapeutic option. The neurological signs of basal ganglia disorder should be evaluated when considering OCD diagnosis, especially in atypical presentation ages. Longitudinal studies are needed to determine the pathogenesis, disease progression and future therapeutic options.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Sign in / Sign up

Export Citation Format

Share Document