Apparent methionine auxotrophy of some tumour cell lines may be linked to impaired amino acid transport

1981 ◽  
Vol 17 (12) ◽  
pp. 1323-1329 ◽  
Author(s):  
Michael J. Tisdale
Keyword(s):  
Amino Acid ◽  
Cell Lines ◽  
Tumour Cell ◽  
Amino Acid Transport ◽  
Acid Transport ◽  
Tumour Cell Lines

Proliferation-dependent changes in amino acid transport and glucose metabolism in glioma cell lines

2004 ◽  
Vol 31 (9) ◽  
Author(s):  
Toshio Sasajima ◽  
Tadashi Miyagawa ◽  
Takamitsu Oku ◽  
JuriG. Gelovani ◽  
Ronald Finn ◽  
...  
Keyword(s):  
Amino Acid ◽  
Glucose Metabolism ◽  
Cell Lines ◽  
Amino Acid Transport ◽  
Glioma Cell ◽  
Acid Transport ◽  
Glioma Cell Lines

scholarly journals Increased Cat3-mediated Cationic Amino Acid Transport Functionally Compensates inCat1Knockout Cell Lines

1998 ◽  
Vol 273 (24) ◽  
pp. 14663-14666 ◽  
Author(s):  
Benjamin Nicholson ◽  
Tatsuya Sawamura ◽  
Tomoh Masaki ◽  
Carol L. MacLeod
Keyword(s):  
Amino Acid ◽  
Cell Lines ◽  
Amino Acid Transport ◽  
Acid Transport ◽  
Cationic Amino Acid

Evidence for Distinct Amino Acid Transport Systems in Cultured Tobacco Cells

1978 ◽  
Vol 33 (9-10) ◽  
pp. 641-645 ◽  
Author(s):  
Jochen Berlin ◽  
Ulrich Mutert
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Aspartic Acid ◽  
Cell Lines ◽  
Amino Acid Transport ◽  
Transport Systems ◽  
Tobacco Cell ◽  
Acid Transport ◽  
Basic Amino Acids ◽  
Neutral Amino Acids

Abstract It is shown by competition experiments that tobacco cell lines have distinct transport systems for ʟ-amino acids. For all tested amino acids the Lineweaver-Burk plots were diphasic indicating the presence of more than one carrier for any one amino acid. Moreover distinct transport systems for neutral, acidic and basic amino acids were kinetically characterized. Based on competition experiments neutral amino acids were absorbed by all transport systems. Aspartic acid entered the cells via its own carrier and via the basic carrier while arginine was taken up only by the basic carrier. Neutral amino acids such as ʟ-leucine or ʟ-phenylalanine were taken up faster than acidic or basic amino acids.

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