Dopamine metabolism in the tuberculum olfactorium

1975 ◽  
Vol 30 (1) ◽  
pp. 117-120 ◽  
Author(s):  
Sherwin Wilk ◽  
Eric Watson ◽  
Stanley D. Glick
Keyword(s):  
Dopamine Metabolism ◽  
Tuberculum Olfactorium

Noncataleptic neuroleptic agents: Synthesis of some esters of 2-chloro-10-(4-(2-hydroxyethyl)piperazino)-10,11-dihydrodibenzo[b,f]thiepin

1986 ◽  
Vol 51 (7) ◽  
pp. 1503-1508
Author(s):  
Jiří Jílek ◽  
Martin Valchář ◽  
Josef Pomykáček ◽  
Antonín Dlabač ◽  
Miroslav Protiva
Keyword(s):  
Rat Brain ◽  
Succinic Anhydride ◽  
Dopamine Metabolism ◽  
Low Doses ◽  
Brain Striatum

Reactions of 2-chloro-10-(4-(2-hydroxyethyl)piperazino)-10,11-dihydrodibenzo[b,f]thiepin (I) with phenylacetic, methoxyacetic, methylthioacetic, phenoxyacetic and morpholinoacetic acid in dichloromethane and in the presence of N,N'-carbonyldiimidazole gave the title esters II - VI. Reaction of I with succinic anhydride afforded the hemisuccinate VII. The esters prepared elicited ataxia in low doses, were low-cataleptic, but only II, IV, and VII proved some antidopaminergic activity in the test using the affecting dopamine metabolism in rat brain striatum.

A possible new role for fish retinal serotonin-N-acetyltransferase-1 (AANAT1): Dopamine metabolism

2006 ◽  
Vol 1073-1074 ◽  
pp. 220-228 ◽  
Author(s):  
Bina Zilberman-Peled ◽  
Benny Ron ◽  
Aviva Gross ◽  
John P.M. Finberg ◽  
Yoav Gothilf
Keyword(s):  
Dopamine Metabolism

Increases in dopamine metabolism are not a general feature of intracranial self-stimulation

Life Sciences ◽  
1982 ◽  
Vol 30 (13) ◽  
pp. 1081-1085 ◽  
Author(s):  
M.J. Mitchell ◽  
N.M. Nicolaou ◽  
G.W. Arbuthnott ◽  
C.M. Yates
Keyword(s):  
General Feature ◽  
Dopamine Metabolism ◽  
Self Stimulation

Mescaline: Its effects on learning rate and dopamine metabolism in goldfish (Carassius auratus)

1976 ◽  
Vol 32 (11) ◽  
pp. 1453-1454 ◽  
Author(s):  
E. A. Zeller ◽  
G. S. Couper ◽  
S. V. Huprikar ◽  
A. M. Mellow ◽  
R. R. Moody
Keyword(s):  
Carassius Auratus ◽  
Dopamine Metabolism ◽  
Learning Rate ◽  
Goldfish Carassius Auratus

MK801 impairs thermoregulation in the heat

2002 ◽  
Vol 80 (3) ◽  
pp. 226-232 ◽  
Author(s):  
Frédéric Canini ◽  
Nadine Simler ◽  
Lionel Bourdon
Keyword(s):  
Locomotor Activity ◽  
Nmda Receptor ◽  
Receptor Antagonist ◽  
Core Temperature ◽  
Exposure Duration ◽  
Heat Exposure ◽  
Nmda Receptor Antagonist ◽  
Dopamine Metabolism ◽  
Body Core Temperature ◽  
Body Core

The effects of MK801 (dizocilpine), a glutamate NMDA receptor antagonist, on thermoregulation in the heat were studied in awake rats exposed to 40°C ambient temperature until their body core temperature reached 43°C. Under these conditions, MK801-treated rats exhibited enhanced locomotor activity and a steady rise in body core temperature, which reduced the heat exposure duration required to reach 43°C. Since MK801-treated rats also showed increased striatal dopaminergic metabolism at thermoneutrality, the role of dopamine in the MK801-induced impairment of thermoregulation in the heat was determined using co-treatment with SCH23390, a dopamine D1 receptor antagonist. SCH23390 normalized the locomotor activity in the heat without any effect on the heat exposure duration. These results suggest that the MK801-induced impairment of thermoregulation in the heat is related to neither a dopamine metabolism alteration nor a locomotor activity enhancement.Key words: heatstroke, NMDA receptor, thermoregulation, dopamine, locomotion.

XVIII.—The Morphology of the Prosencephalon of Spinax as a type of Elasmobranch Fore-brain.

1919 ◽  
Vol 52 (2) ◽  
pp. 487-500 ◽  
Author(s):  
J. Stuart Thomson
Keyword(s):  
Tuberculum Olfactorium ◽  
The Brain ◽  
Mutual Agreement

This investigation on the morphology of the Fore-brain or Prosencephalon of Elasmobranchii was suggested to me by Professor G. Elliot Smith, F.R.S., and I am indebted to him for introducing me to an interesting if somewhat difficult and perplexing subject. A glance at the literature on the morphology of the prosencephalon will readily convince one of two things—firstly, of the endless field for work in endeavouring to ascertain the true homologies of the neurone areas and fibre tracts in the brain throughout the Phylum Vertebrata; and secondly, of the somewhat unnecessary obstacles which have been introduced into the problem by the more recent additions to a terminology, already overburdened and encumbered, of new terms for equivalent parts. It would appear to be very advantageous if mutual agreement could be arrived at among workers on this subject regarding the use of descriptive terms, and, if such is at present impracticable, that each new worker should refrain as far as possible from applying a new term to a structure already previously described. In one case, namely, that of the tuberculum olfactorium, five different terms have apparently been applied to the same area.

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