scholarly journals Nucleotide sequence divergence and functional constraint in VIP precursor mRNA evolution between human and rat

FEBS Letters ◽  
1985 ◽  
Vol 183 (1) ◽  
pp. 55-59 ◽  
Author(s):  
Mikio Nishizawa ◽  
Yumiko Hayakawa ◽  
Noboru Yanaihara ◽  
Hiroshi Okamoto
BMC Genomics ◽  
2013 ◽  
Vol 14 (1) ◽  
pp. 489 ◽  
Author(s):  
Le Tang ◽  
Yang Li ◽  
Xia Deng ◽  
Randal N Johnston ◽  
Gui-Rong Liu ◽  
...  

2006 ◽  
Vol 134 (6) ◽  
pp. 1333-1344 ◽  
Author(s):  
S. ESSBAUER ◽  
J. SCHMIDT ◽  
F. J. CONRATHS ◽  
R. FRIEDRICH ◽  
J. KOCH ◽  
...  

A micro-epidemic of hantavirus infections occurred in Lower Bavaria, South-East Germany, starting in April 2004. While only three cases were registered from 2001 to 2003, a dramatically increased number of clinically apparent human hantavirus infections (n=38) was observed in 2004, plus seven additional cases by June 2005. To determine the reservoir responsible for the infections, a total of 43 rodents were trapped in Lower Bavaria. Serological and genetic investigations revealed that Puumala virus (PUUV) is dominant in the local population of bank voles. Partial PUUV S segment nucleotide sequences originating from bank voles at four different trapping sites in Lower Bavaria showed a low divergence (up to 3·1%). This is contrasted by a nucleotide sequence divergence of 14–16% to PUUV strains detected in Belgium, France, Slovakia or North-Western Germany. PUUV sequences from bank voles in Lower Bavaria represent a new PUUV subtype which seems to be responsible for the observed increase of human hantavirus infections in 2004–2005.


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