scholarly journals An immunodominant antigen of Brugia malayi is an asparaginyl-tRNA synthetase

FEBS Letters ◽  
1995 ◽  
Vol 374 (1) ◽  
pp. 122-124 ◽  
Author(s):  
Michael Kron ◽  
Kristine Marquard ◽  
Michael Härtlein ◽  
Steven Price ◽  
Reuben Leberman
Keyword(s):  
Brugia Malayi ◽  
Trna Synthetase ◽  
Immunodominant Antigen

scholarly journals Adipostatins A–D from Streptomyces sp. 4875 inhibiting Brugia malayi asparaginyl-tRNA synthetase and killing adult Brugia malayi parasites

2015 ◽  
Vol 68 (8) ◽  
pp. 540-542 ◽  
Author(s):  
Mostafa E Rateb ◽  
Dong Yang ◽  
Sanja Vodanovic-Jankovic ◽  
Zhiguo Yu ◽  
Michael A Kron ◽  
...  
Keyword(s):  
Brugia Malayi ◽  
Trna Synthetase ◽  
Streptomyces Sp

Expression, localization and alternative function of cytoplasmic asparaginyl-tRNA synthetase in Brugia malayi

2003 ◽  
Vol 129 (1) ◽  
pp. 33-39 ◽  
Author(s):  
Michael Kron ◽  
Michael Petridis ◽  
Youli Milev ◽  
Joseph Leykam ◽  
Michael Härtlein
Keyword(s):  
Brugia Malayi ◽  
Trna Synthetase ◽  
Alternative Function

scholarly journals Brugia malayi Asparaginyl - tRNA Synthetase Stimulates Endothelial Cell Proliferation, Vasodilation and Angiogenesis

PLoS ONE ◽  
2016 ◽  
Vol 11 (1) ◽  
pp. e0146132 ◽  
Author(s):  
Jeeva Jothi D ◽  
Muthu Dhanraj ◽  
Shanmugam Solaiappan ◽  
Sanjana Sivanesan ◽  
Michael Kron ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Endothelial Cell ◽  
Brugia Malayi ◽  
Trna Synthetase ◽  
Endothelial Cell Proliferation

scholarly journals Get “Hooked” On Brugia malayi Asparaginyl tRNA Synthetase

2009 ◽  
Vol 23 (S1) ◽  
Author(s):  
Amanda Arnold ◽  
Amanda Schulman ◽  
Charles Bach ◽  
Sam Bach ◽  
Andy Faught ◽  
...  
Keyword(s):  
Brugia Malayi ◽  
Trna Synthetase

scholarly journals Correction: Brugia malayi Asparaginyl—tRNA Synthetase Stimulates Endothelial Cell Proliferation, Vasodilation and Angiogenesis

PLoS ONE ◽  
2017 ◽  
Vol 12 (2) ◽  
pp. e0171402
Author(s):  
Jeeva Jothi D ◽  
Muthu Dhanraj ◽  
Shanmugam Solaiappan ◽  
Sanjana Sivanesan ◽  
Michael Kron ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Endothelial Cell ◽  
Brugia Malayi ◽  
Trna Synthetase ◽  
Endothelial Cell Proliferation

Discovering New Classes of Brugia malayi Asparaginyl-tRNA Synthetase Inhibitors and Relating Specificity to Conformational Change

2006 ◽  
Vol 20 (3) ◽  
pp. 159-178 ◽  
Author(s):  
Sai Chetan K. Sukuru ◽  
Thibaut Crepin ◽  
Youli Milev ◽  
Liesl C. Marsh ◽  
Jonathan B. Hill ◽  
...  
Keyword(s):  
Conformational Change ◽  
Brugia Malayi ◽  
Trna Synthetase

scholarly journals Molecular cloning of an immunodominant antigen of Onchocerca volvulus.

1988 ◽  
Vol 168 (3) ◽  
pp. 1199-1204 ◽  
Author(s):  
R Lucius ◽  
N Erondu ◽  
A Kern ◽  
J E Donelson
Keyword(s):  
Adult Worm ◽  
Molecular Cloning ◽  
Dirofilaria Immitis ◽  
Cdna Sequence ◽  
Brugia Malayi ◽  
Recombinant Antigen ◽  
Onchocerca Volvulus ◽  
Structural Protein ◽  
Immunodominant Antigen

We have cloned and characterized the gene for an immunodominant antigen of O. volvulus that is recognized by the sera of 96% of patients with onchocerciasis. Its 1.2-kb mRNA constitutes 0.3% of adult worm poly(A)+ RNA and its cDNA sequence reveals that it is not a highly conserved structural protein such as actin or tubulin. Similar but not identical genes occur in the genomes of related filarie, Brugia malayi and Dirofilaria immitis. The recombinant antigen has both immunodiagnostic and immunoprophylactic significance.

Immune Response to Brugia malayi Asparaginyl-tRNA Synthetase in Balb/c Mice and Human Clinical Samples of Lymphatic Filariasis

2019 ◽  
Vol 17 (4) ◽  
pp. 447-456 ◽  
Author(s):  
Afaq Hameed ◽  
Mahalakshmi Natarajan ◽  
Salih Jabbar ◽  
Jeeva Jothi Dhanasekaran ◽  
Krishna Kumar ◽  
...  
Keyword(s):  
Immune Response ◽  
Lymphatic Filariasis ◽  
Brugia Malayi ◽  
Trna Synthetase ◽  
Clinical Samples

A Hybrid Structural Model of the Complete Brugia malayi Cytoplasmic Asparaginyl-tRNA Synthetase

2011 ◽  
Vol 405 (4) ◽  
pp. 1056-1069 ◽  
Author(s):  
Thibaut Crepin ◽  
Francis Peterson ◽  
Michael Haertlein ◽  
Davin Jensen ◽  
Cheng Wang ◽  
...  
Keyword(s):  
Structural Model ◽  
Brugia Malayi ◽  
Trna Synthetase
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