Red blood cell cholesterol levels, plasma cholesterol esterification rate and serum lipids and lipoproteins in men with hypercholesterolaemia and normal men during 16 weeks physical training

1983 ◽  
Vol 47 (2) ◽  
pp. 145-157 ◽  
Author(s):  
W.H.F. Sutherland ◽  
E.R. Nye ◽  
S.P. Woodhouse
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Physical Training ◽  
Serum Lipids ◽  
Plasma Cholesterol ◽  
Cholesterol Esterification ◽  
Cholesterol Levels ◽  
Esterification Rate ◽  
Normal Men ◽  
Lipids And Lipoproteins

scholarly journals Effects of a water-soluble phytostanol ester on plasma cholesterol levels and red blood cell fragility in hamsters

Lipids ◽  
2005 ◽  
Vol 40 (2) ◽  
pp. 175-180 ◽  
Author(s):  
Naoyuki Ebine ◽  
Xiaoming Jia ◽  
Isabelle Demonty ◽  
Yanwen Wang ◽  
Peter J. H. Jones
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Plasma Cholesterol ◽  
Water Soluble ◽  
Cholesterol Levels

scholarly journals Changes in Serum Lipids from Egg Consumption Are Associated with Clinical Erythrocyte Indices (P08-093-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Julia Greco ◽  
Allison Sloan ◽  
Christa Palancia Esposito ◽  
Aaron Van Dyke ◽  
Catherine Andersen
Keyword(s):  
Blood Cell ◽  
Total Cholesterol ◽  
Red Blood Cell ◽  
Serum Lipids ◽  
Hdl Cholesterol ◽  
Distribution Width ◽  
Erythrocyte Indices ◽  
Cell Counts ◽  
Blood Cell Counts ◽  
Induced Changes

Abstract Objectives Serum lipids may influence the lifespan of erythrocytes, and have been associated with clinical erythrocyte indices at the population level. Consumption of whole eggs vs. egg whites exerts varying effects on serum lipids and lipoprotein profiles; therefore, we investigated whether egg-induced changes in serum lipids correspond to changes in clinical erythrocyte markers. Methods Young, healthy men and women (18–35y, BMI < 30 kg/m2, n = 11) were recruited to participate in an ongoing intervention trial. All subjects followed an egg-free diet for 4 weeks, then were randomized to consume either 3 whole eggs or 3 egg whites per day for 4 weeks. Fasting serum lipids, complete blood cell counts, and dietary intake analysis was performed at the end of each study period. Results Average serum lipids and erythrocyte indices were within normal ranges at the end of each diet period. Changes in total cholesterol following the whole egg (+4.8%) and egg white (0.4%) diet period were not significant as compared to the egg-free diet period. Similarly, clinical erythrocyte markers were not significantly altered by daily consumption of whole eggs or egg whites. However, changes in total cholesterol and LDL-cholesterol between diet periods were positively correlated with changes in total red blood cell counts and hemoglobin. Total cholesterol was additionally correlated with hematocrit levels, and negatively associated with red cell distribution width. Total red blood cell counts and hemoglobin were further correlated with changes in the total cholesterol to HDL-cholesterol ratios, but not HDL-cholesterol alone. Conclusions Our findings indicate that egg-induced changes in serum lipids are associated with clinical erythrocyte indices, and that total cholesterol levels and dyslipidemia may be more significant determinants of erythrocyte profiles. Funding Sources This study was funded by an Agriculture and Food Research Initiative Grant from the USDA National Institute of Food and Agriculture.

Effect Of Plasma Cholesterol On Red Blood Cell Oxygen Transport

2000 ◽  
Vol 27 (12) ◽  
pp. 951-955 ◽  
Author(s):  
Henry Buchwald ◽  
Thomas J O'Dea ◽  
Hector J Menchaca ◽  
Van N Michalek ◽  
Thomas D Rohde
Keyword(s):  
Blood Cell ◽  
Oxygen Transport ◽  
Red Blood Cell ◽  
Plasma Cholesterol

Plasma cholesterol and red blood cell 2,3-diphosphoglycerate

Transfusion ◽  
1982 ◽  
Vol 22 (5) ◽  
pp. 399-399
Author(s):  
AA Nanji ◽  
L Wadsworth ◽  
J Frohlich
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Plasma Cholesterol

scholarly journals Structural features of the lipid bilayer of the red blood cell membrane in people with isolated hypercholesterolemia without coronary artery disease and in patients with coronary artery disease

2017 ◽  
Vol 89 (4) ◽  
pp. 39-44
Author(s):  
A P Vasilev ◽  
N N Streltsova ◽  
N L Lystsova
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Angina Pectoris ◽  
Cell Membrane ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Free Cholesterol ◽  
Red Blood Cell Membrane ◽  
Cholesterol Levels ◽  
Artery Disease

Aim. To identify the specific features of modifying the lipid composition of the red blood cell membrane in people with isolated hypercholesterolemia without coronary heart disease (CHD) and in CHD patients with different functional classes of angina pectoris. Subjects and methods. 92 men with Functional Class II—IV stable angina, 22 men with isolated hypercholesterolemia (HC) without CHD, and 18 healthy men with normal cholesterol levels were examined. Blood plasma cholesterol levels were determined in all the examinees. The erythrocyte membrane was examined for the levels of lipid peroxidation (LPO) products, free cholesterol, calcium, and phospholipid fractions and for the activity of Na+/K+-, Mg2+- and Ca2+-ATPases; a bicycle exercise test was carried out. Results. As compared with persons with normal blood cholesterol levels, the examinees with HC without CHD were found to have higher levels of LPO products, lower levels of readily oxidizable phospholipid fractions, decreased activity of membrane-bound Na+/K+-, Mg2+-, and Ca2+-ATPases, and elevated concentrations of free cholesterol and calcium in the red blood cell membrane. Having the pronounced activity of free radical oxidation, the patients with CHD were detected to have deeper similar structural changes in the cell membrane, which became more severe with a larger number of affected coronary arteries. Conclusion. The findings suggest that the lipid structure of the cell membrane undergoes changes associated with its functional depression just at the preclinical stage of atherogenesis. Biomembrane structural modification in patients with angina pectoris progresses in proportion to the number of affected coronary arteries, by limiting the functional reserve of the cell and whole body.

Plasma Lipid and Lipoprotein Abnormalities in Patients with Malabsorption

1973 ◽  
Vol 45 (5) ◽  
pp. 583-592 ◽  
Author(s):  
Gilbert R. Thompson ◽  
J. Paul Miller
Keyword(s):  
Plasma Lipids ◽  
Plasma Cholesterol ◽  
Low Density Lipoprotein ◽  
Plasma Lipid ◽  
Density Lipoprotein ◽  
Serum Triglyceride ◽  
Plasma Lipoproteins ◽  
Low Density ◽  
Cholesterol Levels ◽  
Lipids And Lipoproteins

1. Plasma lipids and lipoproteins have been studied in control subjects and patients with various types of steatorrhoea. 2. Low plasma cholesterol levels were found in malabsorbers and were associated with decreased amounts of low-density lipoprotein (LDL) in males and high-density lipoprotein (HDL) in females. 3. Serum triglyceride levels were normal in males, but exceeded control values in some of the females, due to an increase in very-low-density lipoprotein. 4. LDL composition was abnormal in both male and female malabsorbers, with a decreased proportion of cholesterol ester and an increased proportion of triglyceride. There was also an increased proportion of triglyceride in HDL. 5. These findings show that malabsorption markedly influences not only the concentration but also the composition of plasma lipoproteins.

Sign in / Sign up

Export Citation Format

Share Document