Effect of short — chain fatty acids on electrical activity of the small intestinal mucosa of rat

Life Sciences ◽  
1981 ◽  
Vol 28 (9) ◽  
pp. 983-989 ◽  
Author(s):  
Takaji Yajima ◽  
Kenji Kojima ◽  
Kiyoshi Tohyama ◽  
Masahiko Mutai
Keyword(s):  
Fatty Acids ◽  
Electrical Activity ◽  
Intestinal Mucosa ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Small Intestinal Mucosa ◽  
Small Intestinal ◽  
Chain Fatty Acids

scholarly journals Intraluminal injection of short chain fatty acids diminishes intestinal mucosa injury in experimental ischemia-reperfusion

2006 ◽  
Vol 21 (1) ◽  
pp. 21-25 ◽  
Author(s):  
José Eduardo de Aguilar-Nascimento ◽  
Alberto Bicudo Salomão ◽  
Rubens Jardim Nochi Jr. ◽  
Mariana Nascimento ◽  
José de Souza Neves
Keyword(s):  
Fatty Acids ◽  
Small Bowel ◽  
Intestinal Mucosa ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Mucosal Injury ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Small Bowel Mucosa ◽  
Chain Fatty Acids

PURPOSE: Investigated the effect of intraluminal short-chain fatty acids (SCFA) on the intestinal mucosa in the presence of ischemia-reperfusion injury (IRI). METHODS: Six blind sacs of the small bowel (3at the jejunum and 3 at the ileum) were created in ten Wistar rats. The lateral sacs of both bowel regions were subjected to IRI (15/15 minutes) while the medial sacs were let free to receive blood supply. In the lateral sacs, it was injected either a solution containing SCFA (butyrate, propionate and acetate) or pure saline at the bowel lumen. No fluid was injected in the medial sacs. RESULTS: Both at the jejunum and at the ileum the score of the mucosal injury was higher in saline than in control sacs. SCFA treated sacs showed lesser score at the ileum (p=0.03) but were not significantly different at the jejunum (p=0.83) when compared with saline sacs. It was found a significant greater number of neutrophils (p < 0.01) in the sacs treated with saline than in the other two sacs in both regions. CONCLUSION: SCFA protect the distal small bowel mucosa and diminishes infiltration of neutrophils to the gut lamina propria in IRI.

scholarly journals Protection by Short-Chain Fatty Acids against 1-β-d-Arabinofuranosylcytosine-Induced Intestinal Lesions in Germfree Mice

1999 ◽  
Vol 43 (4) ◽  
pp. 950-953 ◽  
Author(s):  
Mariana Gontijo Ramos ◽  
Eduardo Alves Bambirra ◽  
Jacques Robert Nicoli ◽  
Denise Carmona Cara ◽  
Enio Cardillo Vieira ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Small Intestine ◽  
Intestinal Mucosa ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Intestinal Lesions ◽  
Chain Fatty Acids

ABSTRACT In germfree mice, the administration of short-chain fatty acids (SCFA) protected the intestinal mucosa from damage produced by 1-β-d-arabinofuranosylcytosine (Ara-C). Animals receiving SCFA and Ara-C had intestinal morphologies closer to normal than the control animals, which had severe intestinal lesions. We concluded that orally administrated SCFA reduce intestinal lesions, improving the mucosa pattern of the small intestine and colon.

Effect of short-chain fatty acids on the ethylene pathway in embryonic axes of Cicer arietinum during germination

1994 ◽  
Vol 92 (4) ◽  
pp. 629-635 ◽  
Author(s):  
Mercedes Gallardo ◽  
Paloma Munoz De Rueda ◽  
Angel Jesus Matilla ◽  
Isabel Maria Sanchez-Calle
Keyword(s):  
Fatty Acids ◽  
Cicer Arietinum ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Embryonic Axes ◽  
Chain Fatty Acids

Short-Chain Fatty Acids Prevent Diabetic Nephropathy In Vivo and In Vitro

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 92-OR ◽  
Author(s):  
WEI HUANG ◽  
YONG XU ◽  
YOUHUA XU ◽  
LUPING ZHOU ◽  
CHENLIN GAO
Keyword(s):  
Fatty Acids ◽  
Diabetic Nephropathy ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Chain Fatty Acids

1898-P: Colonic Short-Chain Fatty Acids Lower Endogenous Glucose Production

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 1898-P
Author(s):  
ADELINA I.L. LANE ◽  
SAVANNA N. WENINGER ◽  
FRANK DUCA
Keyword(s):  
Fatty Acids ◽  
Glucose Production ◽  
Short Chain Fatty Acids ◽  
Endogenous Glucose Production ◽  
Short Chain ◽  
Endogenous Glucose ◽  
Chain Fatty Acids

Concentrations and Correlations of Faecal Short-chain Fatty Acids and Faecal Water Content in Man

1994 ◽  
Vol 7 (6) ◽  
Author(s):  
U. Siigur ◽  
K. E. Norin ◽  
G. Allgood ◽  
T. Schlagheck ◽  
Tore Midtvedt
Keyword(s):  
Fatty Acids ◽  
Water Content ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Chain Fatty Acids
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