Measurement of L-dihydroxyphenylalanine in plasma and other biological fluids by high pressure liquid chromatography with electrochemical detection

Life Sciences ◽  
1982 ◽  
Vol 31 (15) ◽  
pp. 1541-1545 ◽  
Author(s):  
Andrew Shum ◽  
Glen R. Van Loon ◽  
Michael J. Sole
Keyword(s):  
High Pressure ◽  
Liquid Chromatography ◽  
Electrochemical Detection ◽  
High Pressure Liquid Chromatography ◽  
Biological Fluids

scholarly journals An accurate and sensitive analysis by high-pressure liquid chromatography of conjugated and unconjugated bilirubin IX-α in various biological fluids

1980 ◽  
Vol 185 (1) ◽  
pp. 281-284 ◽  
Author(s):  
S Onishi ◽  
S Itoh ◽  
N Kawade ◽  
K Isobe ◽  
S Sugiyama
Keyword(s):  
High Pressure ◽  
Liquid Chromatography ◽  
High Pressure Liquid Chromatography ◽  
Glucuronic Acid ◽  
Biological Fluids ◽  
Reversed Phase ◽  
Complete Separation ◽  
Bile Pigments ◽  
Human Bile ◽  
Neonatal Liver

An accurate and sensitive method was developed for the complete separation of the native tetrapyrroles, such as bilirubin and its mono- and di-conjugates of glucuronic acid, glucose and xylose, by ion-pair reversed-phase high-pressure liquid chromatography. The application of this method was demonstrated by the analysis of bile pigments in human bile and urine, and the method also makes it possible to estimate very low UDP-glucuronyltransferase activity, such as is found in the human foetal and neonatal liver.

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