Presqualene alcohol from Gibberella fujikuroi

1988 ◽  
Vol 27 (2) ◽  
pp. 628-629 ◽  
Author(s):  
W. David Nes ◽  
Eugene E. Van Tamelen ◽  
E.J. Leopold
Keyword(s):  
Gibberella Fujikuroi

Genetic Diversity of Gibberella Fujikuroi Isolates from Different Geographic Origins

1997 ◽  
Vol 25 (3) ◽  
pp. 557-560 ◽  
Author(s):  
Ulrike F. Schlacht ◽  
Evelyn M. Möller ◽  
Hartwig G. Geiger
Keyword(s):  
Genetic Diversity ◽  
Gibberella Fujikuroi ◽  
Geographic Origins

scholarly journals A Genetic Map of Gibberella fujikuroi Mating Population A (Fusarium moniliforme)

Genetics ◽  
1996 ◽  
Vol 143 (1) ◽  
pp. 175-189 ◽  
Author(s):  
Jin-rong Xu ◽  
John F Leslie
Keyword(s):  
Fusarium Moniliforme ◽  
Fragment Length Polymorphism ◽  
Fumonisin B1 ◽  
Gibberella Fujikuroi ◽  
Female Sterility ◽  
Rflp Markers ◽  
Linkage Groups ◽  
Mating Population ◽  
Spore Killer ◽  
Chiasma Interference

Abstract We constructed a recombination-based map of the fungal plant pathogen Gibberella fujikuroi mating population A (asexual stage Fusarium moniliforme). The map is based on the segregation of 142 restriction fragment length polymorphism (RFLP) markers, two auxotrophic genes (arg1, nic1), mating type (matA+ / matA−), female sterility (ste1), spore-killer (Sk), and a gene governing the production of the mycotoxin fumonisin B1 (fum1) among 121 random ascospore progeny from a single cross. We identified 12 linkage groups corresponding to the 12 chromosome-sized DNAs previously observed in contour-clamped homogeneous electric field (CHEF) gels. Linkage groups and chromosomes were correlated via Southern blots between appropriate RFLP markers and the CHEF gels. Eleven of the 12 chromosomes are meiotically stable, but the 12th (and smallest) is subject to deletions in 3% (4/121) of the progeny. Positive chiasma interference occurred on five of the 12 chromosomes, and nine of the 12 chromosomes averaged more than one crossover per chromosome. The average kb/cM ratio in this cross is ~32.

scholarly journals Novel Tandem Biotransformation Process for the Biosynthesis of a Novel Compound, 4-(2,3,5,6-Tetramethylpyrazine-1)-4′-Demethylepipodophyllotoxin

2011 ◽  
Vol 77 (9) ◽  
pp. 3023-3034 ◽  
Author(s):  
Ya-Jie Tang ◽  
Wei Zhao ◽  
Hong-Mei Li
Keyword(s):  
Cell Line ◽  
Alternaria Alternata ◽  
Water Solubility ◽  
Tumor Cell Line ◽  
Gibberella Fujikuroi ◽  
Hydroxyl Group ◽  
Epithelial Cell Line ◽  
The Novel ◽  
Content Type ◽  
Biotransformation Process

ABSTRACTAccording to the structure of podophyllotoxin and its structure-function relationship, a novel tandem biotransformation process was developed for the directional modification of the podophyllotoxin structure to directionally synthesize a novel compound, 4-(2,3,5,6-tetramethylpyrazine-1)-4′-demethylepipodophyllotoxin (4-TMP-DMEP). In this novel tandem biotransformation process, the starting substrate of podophyllotoxin was biotransformed into 4′-demethylepipodophyllotoxin (product 1) with the demethylation of the methoxyl group at the 4′ position byGibberella fujikuroiSH-f13, which was screened out from Shennongjia prime forest humus soil (Hubei, China). 4′-Demethylepipodophyllotoxin (product 1) was then biotransformed into 4′-demethylpodophyllotoxone (product 2) with the oxidation of the hydroxyl group at the 4 position byAlternaria alternataS-f6, which was screened out from the gatheredDysosma versipellisplants in the Wuhan Botanical Garden, Chinese Academy of Sciences. Finally, 4′-demethylpodophyllotoxone (product 2) and ligustrazine were linked with a transamination reaction to synthesize the target product 4-TMP-DMEP (product 3) byAlternaria alternataS-f6. Compared with podophyllotoxin (i.e., a 50% effective concentration [EC50] of 529 μM), the EC50of 4-TMP-DMEP against the tumor cell line BGC-823 (i.e., 0.11 μM) was significantly reduced by 5,199 times. Simultaneously, the EC50of 4-TMP-DMEP against the normal human proximal tubular epithelial cell line HK-2 (i.e., 0.40 μM) was 66 times higher than that of podophyllotoxin (i.e., 0.006 μM). Furthermore, compared with podophyllotoxin (i.e., logP= 0.34), the water solubility of 4-TMP-DMEP (i.e., logP= 0.66) was significantly enhanced by 94%. For the first time, the novel compound 4-TMP-DMEP with superior antitumor activity was directionally synthesized from podophyllotoxin by the novel tandem biotransformation process developed in this work.

Fumonisin producibility of fungicideresistant Gibberella fujikuroi, a pathogen of Bakanae disease

1994 ◽  
Vol 1994 (40) ◽  
pp. 33-37 ◽  
Author(s):  
Takumi YOSHIZAWA ◽  
Mika YAMASAKI ◽  
Naoki NANBA ◽  
Akihiro YAMASHITA ◽  
Susumu UEDA ◽  
...  
Keyword(s):  
Gibberella Fujikuroi ◽  
Bakanae Disease

scholarly journals Comparative Effects of Substituted Pyrimidines on Growth and Gibberellin Biosynthesis in Gibberella fujikuroi

1982 ◽  
Vol 69 (3) ◽  
pp. 712-716 ◽  
Author(s):  
Ronald C. Coolbaugh ◽  
David R. Hell ◽  
Charles A. West
Keyword(s):  
Gibberella Fujikuroi ◽  
Gibberellin Biosynthesis

545. New metabolites of Gibberella fujikuroi. Part II. The isolation of fourteen new metabolites

1963 ◽  
pp. 2937 ◽  
Author(s):  
B. E. Cross ◽  
R. H. B. Galt ◽  
J. R. Hanson ◽  
P. J. Curtis ◽  
John Frederick Grove ◽  
...  
Keyword(s):  
Gibberella Fujikuroi ◽  
New Metabolites

Cephalosporium sacchari. [Distribution map].

1967 ◽  
Author(s):  
Keyword(s):  
South Africa ◽  
North America ◽  
South America ◽  
Dominican Republic ◽  
Central America ◽  
West Indies ◽  
Saccharum Officinarum ◽  
Gibberella Fujikuroi ◽  
Distribution Map ◽  
New Distribution

Abstract A new distribution map is provided for Cephalosporium sacchari[Gibberella fujikuroi var. subglutinans] Butler. Hosts: Sugarcane (Saccharum officinarum). Information is given on the geographical distribution in AFRICA, Madagascar, Réunion, Rhodesia, South Africa, Uganda, ASIA, India, Pakistan, Philippines, CENTRAL AMERICA, WEST INDIES, Barbados, Dominican Republic, Guadeloupe, Trinidad, NORTH AMERICA, Mexico, SOUTH AMERICA, Argentina, Brazil, Colombia.

Gibberella fujikuroi var. subglutinans. [Descriptions of Fungi and Bacteria].

1964 ◽  
Author(s):  
C. Booth
Keyword(s):  
Geographical Distribution ◽  
Sugar Cane ◽  
Stem Borer ◽  
Fruit Rot ◽  
Gibberella Fujikuroi ◽  
Stem Rot ◽  
South Wales ◽  
Pokkah Boeng ◽  
Wide Range ◽  
Southern Rhodesia

Abstract A description is provided for Gibberella fujikuroi var. subglutinans. Information is included on the disease caused by the organism, its transmission, geographical distribution, and hosts. HOSTS: On several hosts of economic importance in the Gramineae; also on a wide range of hosts represented by the following families: Amaryllidaceae, Anacardiaceae, Bromeliaceae, Chenopodiaceae, Convolvulaceae, Cruciferae, Iridaceae, Leguminosae, Liliaceae, Malvaceae, Marantaceae, Musaceae, Palmae, Rosaceae, Rutaceae, Sterculiaceae (14: 708; 31: 515; 36: 501; 40: 89 and Herb. IMI). DISEASES: Causes a seedling blight, and root, stalk and kernel rot of maize; also on heads and stalks of sorghum associated with a foot and stem rot, and causing a stem rot and top rot of sugar-cane ('pokkah boeng'). Other records include a wilt of Crotalaria, a heart rot of leaves of banana and Manila hemp, and fruit rot of banana, cacao and pineapple. There appear to be no references to pathogenicity to rice. Also entomogenous on cereal stem borer larvae and other insects (27: 71; 33: 382; 38: 141, 740). GEOGRAPHICAL DISTRIBUTION: Africa (Central African Republic, Congo, Ghana, Ivory Coast, Kenya, Mauritius, Morocco, Reunion, Sierra Leone, South Africa, Southern Rhodesia, Tanganyika, Uganda); Asia (Formosa (Taiwan), Hong Kong, India, Java, Indo-China, Philippines, Syria); Australasia (Hawaii, New South Wales, New Zealand, Victoria); Europe (Czechoslovakia, Germany,? Italy, Poland, Romania); Central America & West Indies (French Antilles, Honduras, Trinidad); North America (Canada, United States); South America (Argentina, Peru). (CMI Map 191). TRANSMISSION: Both seed and soil-borne. Air-borne ascospores produced from perithecia on over-wintered plant debris or on dead stalks of sugar-cane at the beginning of the rainy season are also important sources of infection (30: 344). The pathogen may also be disseminated on pupae and adults of cereal stem borers and their parasites in sugar-cane (33: 382).

The microbiological transformation of 7α-hydroxy-ent-kaur-16-ene derivatives by Gibberella fujikuroi

2007 ◽  
Vol 68 (11) ◽  
pp. 1557-1563 ◽  
Author(s):  
Braulio M. Fraga ◽  
Carlo Bressa ◽  
Pedro González ◽  
Ricardo Guillermo ◽  
Melchor G. Hernández ◽  
...  
Keyword(s):  
Gibberella Fujikuroi ◽  
Microbiological Transformation
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