In vivo production of childhood acute lymphoblastic leukemia cells in relation to ploidy and immunological subtype

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Giovanni Ucci ◽  
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Key Points The glucocorticoid receptor coordinately regulates the antiapoptotic BCL2 and proapoptotic BIM genes in pediatric ALL cells in vivo. GR binding at a novel intronic region is associated with BIM transcription and dexamethasone sensitivity in pediatric ALL cells in vivo.


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