Synergistic interaction between differentiation inducers and DNA synthesis inhibitors: A new approach to differentiation induction in myelodysplasia and acute myeloid leukaemia

G.E. Francis; J.E.T.E. Guimaraes; J.J. Berney; M.A. Wing

doi:10.1016/0145-2126(85)90136-5

Synergistic interaction between differentiation inducers and DNA synthesis inhibitors: A new approach to differentiation induction in myelodysplasia and acute myeloid leukaemia

Leukemia Research ◽

10.1016/0145-2126(85)90136-5 ◽

1985 ◽

Vol 9 (5) ◽

pp. 573-581 ◽

Cited By ~ 53

Author(s):

G.E. Francis ◽

J.E.T.E. Guimaraes ◽

J.J. Berney ◽

M.A. Wing

Keyword(s):

Acute Myeloid Leukaemia ◽

Dna Synthesis ◽

Myeloid Leukaemia ◽

Synergistic Interaction ◽

New Approach ◽

Differentiation Induction ◽

Differentiation Inducers ◽

Dna Synthesis Inhibitors ◽

Acute Myeloid

Download Full-text

Differentiation in Myelodysplastic, Myeloid Leukaemic and Normal Haemopoietic Cells: A New Approach Exploiting the Synergistic Interaction Between Differentiation Inducers and DNA Synthesis Inhibitors

Modern Trends in Human Leukemia VI New Results in Clinical and Biological Research Including Pediatric Oncology - Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ◽

10.1007/978-3-642-70385-0_83 ◽

1985 ◽

pp. 402-408 ◽

Cited By ~ 1

Author(s):

G. E. Francis ◽

J. E. T. E. Guimaraes ◽

J. J. Berney ◽

M. A. Wing

Keyword(s):

Dna Synthesis ◽

Synergistic Interaction ◽

New Approach ◽

Differentiation Inducers ◽

Haemopoietic Cells ◽

Dna Synthesis Inhibitors

Download Full-text

Low dose cytosine arabinoside: partial remission of acute myeloid leukaemia without evidence of differentiation induction

British Journal of Haematology ◽

10.1111/j.1365-2141.1984.tb02899.x ◽

1984 ◽

Vol 57 (2) ◽

pp. 301-307 ◽

Cited By ~ 47

Author(s):

Michael Leyden ◽

Arumigum Manoharan ◽

Andrew Boyd ◽

Zhao Ming Cheng ◽

John Sullivan

Keyword(s):

Acute Myeloid Leukaemia ◽

Myeloid Leukaemia ◽

Cytosine Arabinoside ◽

Partial Remission ◽

Low Dose ◽

Differentiation Induction ◽

Acute Myeloid

Download Full-text

Variation in Sensitivity of DNA Synthesis to Ara-C in Acute Myeloid Leukaemia

British Journal of Haematology ◽

10.1111/j.1365-2141.1980.tb07157.x ◽

1980 ◽

Vol 45 (3) ◽

pp. 371-379 ◽

Cited By ~ 29

Author(s):

Adrian L. Harris ◽

D. G. Grahame-Smith

Keyword(s):

Acute Myeloid Leukaemia ◽

Dna Synthesis ◽

Myeloid Leukaemia ◽

Acute Myeloid

Download Full-text

Activation of deoxycytidine kinase by inhibition of DNA synthesis in human lymphocytes11Abbreviations: dCK, deoxycytidine kinase; dTK, thymidine kinase; CdA, 2-chloro-2′-deoxyadenosine; araC, 1-β-D-arabinofuranosylcytosine; 3HdC, 2′-deoxy-[5-3H] cytidine; 3HdT, 2′-deoxy-[5-methyl-3H] thymidine; HL 60, human promyelocytic cell line; AML, acute myeloid leukaemia; PBMC, peripherial blood mononuclear cell; APC, aphidicolin; and DEAE, diethylaminoethyl.

Biochemical Pharmacology ◽

10.1016/s0006-2952(00)00534-7 ◽

2001 ◽

Vol 61 (2) ◽

pp. 191-197 ◽

Cited By ~ 29

Author(s):

Zsolt Csapó ◽

Mária Sasvári-Székely ◽

Tatjana Spasokoukotskaja ◽

Iannis Talianidis ◽

Staffan Eriksson ◽

...

Keyword(s):

Acute Myeloid Leukaemia ◽

Dna Synthesis ◽

Myeloid Leukaemia ◽

Cell Line ◽

Thymidine Kinase ◽

Mononuclear Cell ◽

Deoxycytidine Kinase ◽

Inhibition Of Dna Synthesis ◽

Acute Myeloid

Download Full-text

A new approach to the treatment of acute myeloid leukaemia targeting the receptor for growth hormone-releasing hormone

British Journal of Haematology ◽

10.1111/bjh.15207 ◽

2018 ◽

Vol 181 (4) ◽

pp. 476-485 ◽

Cited By ~ 3

Author(s):

Joaquin J. Jimenez ◽

Gina M. DelCanto ◽

Petra Popovics ◽

Aymee Perez ◽

Ailin Vila Granda ◽

...

Keyword(s):

Growth Hormone ◽

Acute Myeloid Leukaemia ◽

Myeloid Leukaemia ◽

Growth Hormone Releasing Hormone ◽

New Approach ◽

Releasing Hormone ◽

Acute Myeloid

Download Full-text

MK 886, an antagonist of leukotriene generation, inhibits DNA synthesis in a subset of acute myeloid leukaemia cells

Leukemia Research ◽

10.1016/0145-2126(93)90109-x ◽

1993 ◽

Vol 17 (9) ◽

pp. 759-762 ◽

Cited By ~ 23

Author(s):

M.Ayyub Khan ◽

A.Victor Hoffbrand ◽

Atul Mehta ◽

Faith Wright ◽

Fariba Tahami ◽

...

Keyword(s):

Acute Myeloid Leukaemia ◽

Dna Synthesis ◽

Myeloid Leukaemia ◽

Acute Myeloid

Download Full-text

Differentiation induction in myelodysplasia and acute myeloid leukaemia: Use of synergistic drug combinations

Leukemia Research ◽

10.1016/0145-2126(87)90115-9 ◽

1987 ◽

Vol 11 (11) ◽

pp. 971-977 ◽

Cited By ~ 18

Author(s):

G.E. Francis ◽

G.J. Mufti ◽

S.M. Knowles ◽

J.J. Berney ◽

J.E.T. Guimaraes ◽

...

Keyword(s):

Acute Myeloid Leukaemia ◽

Myeloid Leukaemia ◽

Drug Combinations ◽

Differentiation Induction ◽

Acute Myeloid ◽

Synergistic Drug Combinations

Download Full-text

The acute myeloid leukaemia market

Nature Reviews Drug Discovery ◽

10.1038/d41573-019-00142-4 ◽

2019 ◽

Vol 19 (4) ◽

pp. 233-234

Author(s):

Jorrit Schaefer ◽

Sorcha Cassidy ◽

Rachel M. Webster

Keyword(s):

Acute Myeloid Leukaemia ◽

Myeloid Leukaemia ◽

Acute Myeloid

Download Full-text

The effects of IL-1Ra and antisense oligonucleotide to IL-1β converting enzyme (ICE) on the production of IL-1β by acute myeloid leukaemia cells

Immunology Letters ◽

10.1016/s0165-2478(97)88159-x ◽

1997 ◽

Vol 56 (1-3) ◽

pp. 326-327

Author(s):

S Stosic-Grujicic

Keyword(s):

Acute Myeloid Leukaemia ◽

Myeloid Leukaemia ◽

Antisense Oligonucleotide ◽

Converting Enzyme ◽

Acute Myeloid

Download Full-text

Author response for "REAL‐WORD EXPERIENCE WITH DECITABINE AS A FIRST‐LINE TREATMENT IN 306 ELDERLY ACUTE MYELOID LEUKAEMIA PATIENTS UNFIT FOR INTENSIVE CHEMOTHERAPY"

10.1002/hon.2663/v2/response1 ◽

2019 ◽

Author(s):

Monica Bocchia ◽

Anna Candoni ◽

Erika Borlenghi ◽

Marzia Defina ◽

Carla Filì ◽

...

Keyword(s):

Acute Myeloid Leukaemia ◽

Myeloid Leukaemia ◽

Author Response ◽

Intensive Chemotherapy ◽

Line Treatment ◽

Real Word ◽

First Line ◽

First Line Treatment ◽

Acute Myeloid

Download Full-text