Transient protection of human T-cells from human immunodeficiency virus type 1 infection by transduction with adeno-associated viral vectors which express RNA decoys

1996 ◽  
Vol 32 (2) ◽  
pp. 99-115 ◽  
Author(s):  
Clay Smith ◽  
Seong-Wook Lee ◽  
Ellen Wong ◽  
Humilidad Gallardo ◽  
Kevin Page ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
T Cells ◽  
Human Immunodeficiency Virus Type ◽  
Virus Type ◽  
Viral Vectors ◽  
Human T Cells ◽  
Immunodeficiency Virus

scholarly journals Role of Cell Surface Glycosaminoglycans of Human T Cells in Human Immunodeficiency Virus Type-1 (HIV-1) Infection

1996 ◽  
Vol 40 (11) ◽  
pp. 827-835 ◽  
Author(s):  
Yukako Ohshiro ◽  
Tsutomu Murakami ◽  
Kazuhiro Matsuda ◽  
Kiyoshi Nishioka ◽  
Keiichi Yoshida ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
T Cells ◽  
Cell Surface ◽  
Human Immunodeficiency Virus Type ◽  
Virus Type ◽  
Human T Cells ◽  
Immunodeficiency Virus ◽  
Hiv 1

scholarly journals A Lentiviral cDNA Library Employing Lambda Recombination Used To Clone an Inhibitor of Human Immunodeficiency Virus Type 1-Induced Cell Death

2004 ◽  
Vol 78 (20) ◽  
pp. 11352-11359 ◽  
Author(s):  
Yuji Kawano ◽  
Takeshi Yoshida ◽  
Kuniko Hieda ◽  
Jun Aoki ◽  
Hiroyuki Miyoshi ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
T Cells ◽  
Cdna Library ◽  
Human Immunodeficiency Virus Type ◽  
Virus Type ◽  
Expression Cloning ◽  
Human T Cells ◽  
Immunodeficiency Virus ◽  
Hiv 1

ABSTRACT Expression cloning technology of cDNAs is a suitable tool for identifying novel functional properties of genes. Here, we generated a lentiviral cDNA library-expressing system for human T cells based on a site-specific recombination system of phage lambda for transferring cDNA libraries with a minimum loss of its complexity. The library-transduced CD4+ T cells were challenged with wild-type human immunodeficiency virus type 1 (HIV-1), and the cells that acquired resistance to HIV-1-induced cytopathic effect (CPE) were selected. From these cells, CD14 was isolated and proved to inhibit the entry of HIV-1 and the HIV-1-induced CPE. This cloning system allows rapid identification of genes encoding novel properties in human T cells and probably other mammalian cells.

scholarly journals The Vif and Gag proteins of human immunodeficiency virus type 1 colocalize in infected human T cells.

1997 ◽  
Vol 71 (7) ◽  
pp. 5259-5267 ◽  
Author(s):  
J H Simon ◽  
R A Fouchier ◽  
T E Southerling ◽  
C B Guerra ◽  
C K Grant ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
T Cells ◽  
Human Immunodeficiency Virus Type ◽  
Virus Type ◽  
Gag Proteins ◽  
Human T Cells ◽  
Immunodeficiency Virus
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