The contrasting effects of cyclosporin-A and azathioprine on arterial blood pressure and renal function following cardiac transplantation

1986 ◽  
Vol 11 (2) ◽  
pp. 219-229 ◽  
Author(s):  
Mark E. Thompson ◽  
Alvin P. Shapiro ◽  
Anna-Margareta Johnsen ◽  
Jerome M. Itzkoff ◽  
Robert L. Hardesty ◽  
...  
2015 ◽  
Vol 120 (3) ◽  
pp. 608-618 ◽  
Author(s):  
Anne Sophie Pinholt Kancir ◽  
Joergen Kühlwein Johansen ◽  
Niels Peter Ekeloef ◽  
Erling Bjerregaard Pedersen

Critical Care ◽  
2013 ◽  
Vol 17 (1) ◽  
pp. R21 ◽  
Author(s):  
Thiago Corrêa ◽  
Madhusudanarao Vuda ◽  
Jukka Takala ◽  
Siamak Djafarzadeh ◽  
Eliézer Silva ◽  
...  

2016 ◽  
Vol 60 (3) ◽  
pp. 118-119
Author(s):  
Anne Sophie Pinholt Kancir ◽  
Joergen Kuhlwein Johansen ◽  
Niels Peter Ekeloef ◽  
Erling Bjerregaard Pedersen

1979 ◽  
Vol 236 (5) ◽  
pp. R297-R301 ◽  
Author(s):  
P. C. Churchill ◽  
R. L. Malvin ◽  
M. C. Churchill ◽  
F. D. McDonald

Arterial blood pressure, urine flow rate, and plasma and urine electrolytes were measured in the aglomerular goosefish (L. americanus) before, during, and after the intravenous infusion of angiotensin II (from 5 to 280 ng/min.kg body wt). Increases in arterial blood pressure were directly related to the logarithm of the angiotensin infusion rate (r = 0.62, P less than 0.005). Angiotensin also increased urine flow from 0.676 +/- 0.065 to 0.755 +/- 0.068 ml/h.kg body wt (P less than 0.005) and Na excretion from 41.0 +/- 5.5 to 54.4 +/- 7.0 mumol/h.kg body wt (P less than 0.001). In 17 of the 19 fish infused with angiotensin the diuretic and natriuretic effects were directly related to the logarithm of the infusion rate (r = 0.44, P less than 0.04 and r = 0.51, P less than 0.02, respectively). There was no relationship between the pressor and the diuretic or natriuretic effects of angiotensin II. These results are consistent with inhibitory effects of angiotensin on solute transport by aglomerular tubules.


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