Examination of phosphorylated tau protein as a PHF-precursor at early stage alzheimer's disease

1995 ◽  
Vol 16 (3) ◽  
pp. 433-445 ◽  
Author(s):  
Robert Y.K. Lai ◽  
Herman N.-J. Gertz ◽  
Damon J. Wischik ◽  
John H. Xuereb ◽  
Elizabeth B. Mukaetova-Ladinska ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Tau Protein ◽  
Early Stage ◽  
Phosphorylated Tau ◽  
Phosphorylated Tau Protein

Assay of Plasma Phosphorylated Tau Protein (Threonine 181) and Total Tau Protein in Early-Stage Alzheimer’s Disease

2018 ◽  
Vol 61 (4) ◽  
pp. 1323-1332 ◽  
Author(s):  
Che-Chuan Yang ◽  
Ming-Jang Chiu ◽  
Ta-Fu Chen ◽  
Hui-Ling Chang ◽  
Bing-Hsien Liu ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Tau Protein ◽  
Early Stage ◽  
Phosphorylated Tau ◽  
Total Tau ◽  
Phosphorylated Tau Protein

Phosphorylated tau protein in cerebrospinal fluid is elevated in Alzheimer's disease and other tauopathies

2000 ◽  
Vol 21 ◽  
pp. 155
Author(s):  
Katsuya Urakami ◽  
Hiroyuki Arai ◽  
Koichi Ishiguro ◽  
Hideto Ohno ◽  
Hideki Kohno ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cerebrospinal Fluid ◽  
Tau Protein ◽  
Phosphorylated Tau ◽  
Phosphorylated Tau Protein

scholarly journals Association of cellular and subcellular calcification with phosphorylated tau in the brains of Alzheimer’s disease patients

2020 ◽  
Author(s):  
Elena Tsolaki ◽  
Lajos Csincsik ◽  
Jing Xue ◽  
Imre Lengyel ◽  
Sergio Bertazzo
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Tau Protein ◽  
Detection Method ◽  
Phosphorylated Tau ◽  
Cell Nuclei ◽  
Middle Temporal ◽  
Early Marker ◽  
Phosphorylated Tau Protein

ABSTRACTDeposition of tau-tangles is an early marker for the development of Alzheimer’s disease (AD). Here we show that these aggregates of phosphorylated tau protein are associated with the calcification of cell nuclei and cell projections, especially in the middle temporal, superior temporal and parahippocampal gyri. This calcification is related to the aetiology of the disease, shedding new light on the mechanisms involved in AD and potentially providing a new detection method for AD progression.

Sign in / Sign up

Export Citation Format

Share Document