Laser Doppler Imaging of Finger Skin Blood Flow in Patients after Microvascular Repair of the Ulnar Artery at the Wrist

1994 ◽  
Vol 19 (3) ◽  
pp. 295-300 ◽  
Author(s):  
S. BORNMYR ◽  
M. ARNER ◽  
H. SVENSSON
Keyword(s):  
Blood Flow ◽  
Skin Blood Flow ◽  
Ulnar Artery ◽  
Laser Doppler ◽  
Doppler Imaging ◽  
Invasive Technique ◽  
Microvascular Reconstruction ◽  
Laser Doppler Imaging ◽  
Non Invasive ◽  
Finger Tip

Laser Doppler imaging is a new, non-invasive technique allowing the spatial distribution and the temporal variation of the skin blood flow to be monitored. A mean blood flow value over an area, such as the finger-tip in the present study, can also be calculated. Recordings from 12 patients with a sutured ulnar artery following trauma did not significantly differ from those obtained in 14 controls. Four patients with a ligated ulnar artery, however, showed a slower restitution of blood flow values after cold provocation. All sutured ulnar arteries were found to be patent, which confirms that microvascular reconstruction of an injury to the ulnar artery at the wrist is worthwhile.

scholarly journals Laser Doppler Imaging of Skin Blood Flow for Assessing Peripheral Vascular Impairment in Hand-Arm Vibration Syndrome

2007 ◽  
Vol 45 (2) ◽  
pp. 309-317 ◽  
Author(s):  
Kazufumi TERADA ◽  
Nobuyuki MIYAI ◽  
Yuki MAEJIMA ◽  
Shunji SAKAGUCHI ◽  
Taro TOMURA ◽  
...  
Keyword(s):  
Blood Flow ◽  
Skin Blood Flow ◽  
Laser Doppler ◽  
Doppler Imaging ◽  
Laser Doppler Imaging ◽  
Peripheral Vascular ◽  
Vibration Syndrome

Vasoactive properties of lignocaine administered by iontophoresis in human skin

2003 ◽  
Vol 104 (1) ◽  
pp. 87-92 ◽  
Author(s):  
David J. NEWTON ◽  
Alexandra K.B. AMYES ◽  
Faisel KHAN ◽  
Graeme A. MCLEOD ◽  
Jonathan BANNISTER ◽  
...  
Keyword(s):  
Blood Flow ◽  
Skin Blood Flow ◽  
Doppler Imaging ◽  
Invasive Technique ◽  
Young Males ◽  
Non Invasive ◽  
Forearm Skin ◽  
The Difference ◽  
Iontophoretic Delivery ◽  
Positively Charged

The vasoactivity of lignocaine has an important influence on its clinical efficacy and systemic vascular absorption. The aim of this study was to evaluate its vasoactive properties when administered by the non-invasive technique of iontophoresis. We used laser Doppler imaging to measure the forearm skin blood flow responses of seven healthy young males to iontophoretic delivery of two preparations of 20g/l of lignocaine hydrochloride, one containing the preservatives methylparaben and propylparaben and one without. The subjects were blind to the order of drug administration, and we assessed analgesia at the sites using a pinprick test. Delivery of both preparations of (positively charged) lignocaine under the anode caused demonstrable analgesia, but no change in skin blood flow. An increase in perfusion was measured, however, when the preservative-containing preparation was administered under the cathode. There was little or no response to the solution without preservatives, although the difference in response between the two preparations was not statistically significant (P = 0.063). Although there were no vasoactive effects of lignocaine at the relatively low dose used in the present study, our results suggest that the preservatives methylparaben and propylparaben are the most likely cause of the vasodilatation that we observed under the cathode, and may therefore have a significant influence on the vasoactivity of this preparation when administered by injection. Both are negatively charged in solution and have been reported to possess vasodilator properties. It might be worth considering the use of alternative, non-vasoactive preservatives in local anaesthetic preparations, or avoiding the use of additives altogether, when this is feasible.

Skin Blood Flow Changes in Response to Intradermal Injection of Bupivacaine and Levobupivacaine, Assessed by Laser Doppler Imaging

2000 ◽  
Vol 25 (6) ◽  
pp. 626-631 ◽  
Author(s):  
David J. Newton ◽  
Daniel Burke ◽  
Faisel Khan ◽  
Graeme A. McLeod ◽  
Jill J.F. Belch ◽  
...  
Keyword(s):  
Blood Flow ◽  
Skin Blood Flow ◽  
Intradermal Injection ◽  
Laser Doppler ◽  
Doppler Imaging ◽  
Laser Doppler Imaging ◽  
Flow Changes
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