Effects of stress on tumor growth and metastasis in mice bearing lewis lung carcinoma

1989 ◽  
Vol 25 (11) ◽  
pp. 1583-1588 ◽  
Author(s):  
T. Giraldi ◽  
L. Perissin ◽  
S. Zorzet ◽  
P. Piccini ◽  
V. Rapozzi
Keyword(s):  
Tumor Growth ◽  
Lung Carcinoma ◽  
Lewis Lung Carcinoma ◽  
Lewis Lung ◽  
Effects Of Stress ◽  
Tumor Growth And Metastasis

Abstract C78: The mu opioid receptor regulates Lewis lung carcinoma tumor growth and metastasis

2009 ◽  
Author(s):  
Biji Mathew ◽  
Frances E. Lennon ◽  
Jessica Siegler ◽  
Lynnette Gerhold ◽  
Nurbek Mambetsariev ◽  
...  
Keyword(s):  
Tumor Growth ◽  
Opioid Receptor ◽  
Lung Carcinoma ◽  
Lewis Lung Carcinoma ◽  
Mu Opioid Receptor ◽  
Lewis Lung ◽  
Mu Opioid ◽  
Tumor Growth And Metastasis ◽  
Carcinoma Tumor

Salinomycin and dichloroacetate synergistically inhibit Lewis lung carcinoma cell proliferation, tumor growth and metastasis

2020 ◽  
Vol 523 (4) ◽  
pp. 874-879 ◽  
Author(s):  
Aistė Skeberdytė ◽  
Ieva Sarapinienė ◽  
Jan Aleksander Krasko ◽  
Aušrinė Barakauskienė ◽  
Karolina Žilionytė ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Tumor Growth ◽  
Lung Carcinoma ◽  
Lewis Lung Carcinoma ◽  
Carcinoma Cell ◽  
Lewis Lung Carcinoma Cell ◽  
Lewis Lung ◽  
Lung Carcinoma Cell ◽  
Tumor Growth And Metastasis

scholarly journals new bIologIcal model of moderate InhIbItIon of tumor and metastases growth wIth prolonged leukopenIa In mIce

2016 ◽  
Vol 1 (5) ◽  
pp. 121-125
Author(s):  
Зуева ◽  
Elena Zueva ◽  
Разина ◽  
Tatyana Razina ◽  
Ермакова ◽  
...  
Keyword(s):  
Tumor Growth ◽  
Lung Carcinoma ◽  
Lewis Lung Carcinoma ◽  
Tumor Therapy ◽  
Biological Model ◽  
Tumor Growth Inhibition ◽  
Lewis Lung ◽  
Inhibition Of Tumor Growth ◽  
Toxic Manifestation ◽  
Cyclophosphamide Dose

A new biological model of moderate inhibition of tumor growth and metastases with prolonged leukopenia on C57Bl/6 mice with the Lewis Lung Carcinoma was designed. The model was created by the injection of cyclophosphamide (dose 83.3mg/kg) on 6th, 12th, 18th days after tumor cells transplantation on animals. Experiment showed that 3-fold cyclo-phosphamide use leads to growth of primary tumor and metastases inhibition. Tumor growth inhibition was 34% on 21st day after cyclophosphamide inject. The number of metastases decreased by 4.7times (p<0,01). Metastatic area reduced. Metastasis frequency made 100%. In addition, the course of cyclophosphamide application caused inhibition of granulocytic and lymphoid hematopoiesis. The reducing the number of segmented neutrophils and lymphocytes was showed on the 3rd day after 1, 2 and 3 injections of cyclophosphamide. The model can be used to study the efficacy of drugs in tumor therapy and in correction of such toxic manifestation of chemotherapy as leukopenia.

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