Lignocaine selectively reduces C fibre-evoked neuronal activity in rat spinal cord in vitro by decreasing N-methyl-D-aspartate and neurokinin receptor-mediated post-synaptic depolarizations; implications for the development of novel centrally acting analgesics

Istvan Nagy; Clifford J. Woolf

doi:10.1016/0304-3959(95)00072-0

Lignocaine selectively reduces C fibre-evoked neuronal activity in rat spinal cord in vitro by decreasing N-methyl-D-aspartate and neurokinin receptor-mediated post-synaptic depolarizations; implications for the development of novel centrally acting analgesics

Pain ◽

10.1016/0304-3959(95)00072-0 ◽

1996 ◽

Vol 64 (1) ◽

pp. 59-70 ◽

Cited By ~ 80

Author(s):

Istvan Nagy ◽

Clifford J. Woolf

Keyword(s):

Spinal Cord ◽

Neuronal Activity ◽

Rat Spinal Cord ◽

Neurokinin Receptor ◽

C Fibre

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Injury-induced plasticity of spinal reflex activity: NK1 neurokinin receptor activation and enhanced A- and C-fiber mediated responses in the rat spinal cord in vitro

Journal of Neuroscience ◽

10.1523/jneurosci.14-06-03672.1994 ◽

1994 ◽

Vol 14 (6) ◽

pp. 3672-3687 ◽

Cited By ~ 123

Author(s):

SW Thompson ◽

A Dray ◽

L Urban

Keyword(s):

Spinal Cord ◽

Receptor Activation ◽

Spinal Reflex ◽

Reflex Activity ◽

Rat Spinal Cord ◽

Neurokinin Receptor ◽

C Fiber

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The selective NK-2 receptor antagonist MEN 10,376 inhibits synaptic excitation of dorsal horn neurons evoked by C-fibre activation in the in vitro rat spinal cord

Neuropeptides ◽

10.1016/0143-4179(92)90507-s ◽

1992 ◽

Vol 22 (1) ◽

pp. 68 ◽

Cited By ~ 13

Author(s):

L. Urban ◽

C.A. Maggi ◽

I. Nagy ◽

A. Dray

Keyword(s):

Spinal Cord ◽

Receptor Antagonist ◽

Dorsal Horn ◽

Rat Spinal Cord ◽

Synaptic Excitation ◽

Dorsal Horn Neurons ◽

C Fibre

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Morphine Selectively Depresses the Slowest, NMDA-independent Component of C-fibre-evoked Synaptic Activity in the Rat Spinal Cord In Vitro

European Journal of Neuroscience ◽

10.1111/j.1460-9568.1995.tb01015.x ◽

1995 ◽

Vol 7 (1) ◽

pp. 12-18 ◽

Cited By ~ 23

Author(s):

L G. Sivilotti ◽

G. Gerber ◽

B. Rawat ◽

C. J. Woolf

Keyword(s):

Spinal Cord ◽

Independent Component ◽

Synaptic Activity ◽

Rat Spinal Cord ◽

C Fibre

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The in vitro neonatal rat spinal cord preparation: a new insight into mammalian locomotor mechanisms

Journal of Comparative Physiology A ◽

10.1007/s00359-004-0499-2 ◽

2004 ◽

Vol 190 (5) ◽

pp. 343-357 ◽

Cited By ~ 35

Author(s):

F. Clarac ◽

E. Pearlstein ◽

J. F. Pflieger ◽

L. Vinay

Keyword(s):

Spinal Cord ◽

Neonatal Rat ◽

Rat Spinal Cord ◽

Insight Into

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Differential effects of muscimol upon the firing frequency of large and small amplitude antidromic dorsal root action potentials in rat spinal cord in vitro

Neuroscience Letters ◽

10.1016/s0304-3940(02)00747-4 ◽

2002 ◽

Vol 330 (2) ◽

pp. 139-142 ◽

Cited By ~ 2

Author(s):

J. Bagust ◽

W.D. Willis

Keyword(s):

Spinal Cord ◽

Action Potentials ◽

Dorsal Root ◽

Small Amplitude ◽

Firing Frequency ◽

Rat Spinal Cord ◽

Differential Effects

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21. Whole-cell recordings from motoneurones in rat spinal cord in vitro with attached dorsal and ventral roots

Journal of Neuroscience Methods ◽

10.1016/0165-0270(94)90081-7 ◽

1994 ◽

Vol 52 (1) ◽

pp. A10

Author(s):

C.Q. Cao ◽

R.H. Evans ◽

P.M. Headley

Keyword(s):

Spinal Cord ◽

Rat Spinal Cord ◽

Whole Cell ◽

Ventral Roots ◽

Whole Cell Recordings

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3-Nitropropionic acid depresses spinal reflexes involving GABAergic and glycinergic transmission in neonatal rat spinal cord in vitro

Life Sciences ◽

10.1016/j.lfs.2008.09.017 ◽

2008 ◽

Vol 83 (21-22) ◽

pp. 756-760 ◽

Cited By ~ 7

Author(s):

Rajesh Gupta ◽

Shripad B. Deshpande

Keyword(s):

Spinal Cord ◽

Spinal Reflexes ◽

Neonatal Rat ◽

Rat Spinal Cord ◽

Nitropropionic Acid ◽

3 Nitropropionic Acid

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Loss of inhibitory synapses causes locomotor network dysfunction of the rat spinal cord during prolonged maintenance in vitro

Brain Research ◽

10.1016/j.brainres.2018.12.029 ◽

2019 ◽

Vol 1710 ◽

pp. 8-21

Author(s):

Antonela Petrovic ◽

Priyadharishini Veeraraghavan ◽

Dario Olivieri ◽

Andrea Nistri ◽

Nina Jurcic ◽

...

Keyword(s):

Spinal Cord ◽

Inhibitory Synapses ◽

Rat Spinal Cord

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The pharmacology of descending responses evoked by thoracic stimulation in the neonatal rat spinal cord in vitro

Naunyn-Schmiedeberg s Archives of Pharmacology ◽

10.1007/bf00166948 ◽

1993 ◽

Vol 347 (6) ◽

pp. 643-651 ◽

Cited By ~ 15

Author(s):

D.I. Wallis ◽

J. Wu

Keyword(s):

Spinal Cord ◽

Neonatal Rat ◽

Rat Spinal Cord

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Dual Control of Central Pattern Generators: Neonatal Rat Spinal Cord In Vitro

Neural Control of Movement ◽

10.1007/978-1-4615-1985-0_24 ◽

1995 ◽

pp. 187-194 ◽

Cited By ~ 2

Author(s):

J.-R. Cazalets

Keyword(s):

Spinal Cord ◽

Central Pattern Generators ◽

Neonatal Rat ◽

Dual Control ◽

Rat Spinal Cord ◽

Pattern Generators

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