Birth order, maternal age and spontaneous abortion

1983 ◽  
Vol 8 (2) ◽  
pp. 179-180 ◽  
Author(s):  
W.H. James
Keyword(s):  
Birth Order ◽  
Spontaneous Abortion ◽  
Maternal Age

Spontaneous Abortion and Birth Order

1974 ◽  
Vol 6 (1) ◽  
pp. 23-41 ◽  
Author(s):  
William H. James
Keyword(s):  
Birth Order ◽  
Spontaneous Abortion ◽  
Maternal Age ◽  
Order Effect ◽  
Pathological Examination ◽  
Spontaneous Abortions ◽  
Birth Rank ◽  
Individual Woman ◽  
Reproductive Life ◽  
Reproductive Compensation

SummaryIt is well established that, in general, pregnancies at advanced maternal ages or of advanced birth order are at greater risk of aborting spontaneously. It does not follow that each individual woman, as she proceeds through her reproductive life, becomes steadily more prone to abort. The present paper attempts to analyse evidence on how individual women's abortion probabilities vary during their reproductive lives. Statistical examination of the data suggests that:1. A spontaneous abortion in a given birth rank is more likely than a live birth in the same rank to be followed by a further pregnancy. Abortion-prone women have more pregnancies than other women.2. There is no significant overall tendency for spontaneous abortions to appear early or late in sibships even when account is taken of the reproductive compensation reported above.3. Pathological examination of spontaneously aborted fetuses suggests that more (perhaps many more) than 10% of spontaneous abortions (e.g. those associated with trisomy and maternal isoimmunization) are causally associated with advanced maternal age or birth order.4. The mean maternal age of spontaneously aborted fetuses which fail to grow in culture is higher than that of fetuses which are successfully cultured.One would infer:A. (from suggestions 1 and 2 above) that reproductive compensation (rather than a real birth order effect) is a major reason why abortion rates are higher at higher maternal ages and higher birth ranks;B. (from suggestions 2 and 3 above) that there must be another group of abortions, roughly equal in number, which are causally associated with low maternal age or early birth order.Little is known about this second group of reproductive casualties (those associated with low birth order or maternal age), but it is suggested that some have CNS malformations. I have made similar suggestions in regard to stillbirth and neonatal death.

Reduced spontaneous abortion and increased live birth rate after PGD for advanced maternal age

2007 ◽  
Vol 88 ◽  
pp. S85-S86 ◽  
Author(s):  
S. Munne ◽  
J. Garrisi ◽  
F. Barnes ◽  
L. Werlin ◽  
W. Schoolcraft ◽  
...  
Keyword(s):  
Spontaneous Abortion ◽  
Live Birth ◽  
Maternal Age ◽  
Birth Rate ◽  
Live Birth Rate ◽  
Advanced Maternal Age

Stillbirth Rate and Weight at Birth of Quintuplets in Japan

1989 ◽  
Vol 38 (1-2) ◽  
pp. 65-69 ◽  
Author(s):  
Yoko Imaizumi
Keyword(s):  
Sample Size ◽  
Birth Order ◽  
Gestational Age ◽  
Size Effects ◽  
Maternal Age ◽  
Small Sample Size ◽  
Small Sample ◽  
Stillbirth Rate ◽  
The Mean

AbstractNation-wide data in Japan on births and prenatal deaths of 16 sets of quintuplets during 1974-1985 were analysed. Among the 16 sets, 3 sets were liveborn, 8 were stillborn, and 5 were mixed, with a stillbirth rate of 0.64 (51/80). Effects of sex, maternal age and birth order on the stillbirth rate were not considered because of the small sample size. Effects of gestational age and birthweight on stillbirth rate were also examined. The mean weight of the 40 quintuplet individuals was 1,048 g.

scholarly journals Impact of High-Risk Fertility Behaviour on Under-five Mortality in Asia and Africa: Evidence from Demographic and Health Surveys

2020 ◽  
Author(s):  
Rafi Amir-ud-Din ◽  
Lubna Naz ◽  
Anila Rubi ◽  
Muhammad Usman ◽  
Umesh Ghimire
Keyword(s):  
Risk Factors ◽  
High Risk ◽  
Birth Order ◽  
Birth Interval ◽  
Health Surveys ◽  
Maternal Age ◽  
Demographic And Health Surveys ◽  
Index Child ◽  
Under Five ◽  
Fertility Behaviour

Abstract Background: Smaller or older maternal age, smaller inter-pregnancy birth interval, and higher birth order of the child are considered to be high-risk fertility behaviour (HRFB). Under-five mortality being disproportionately concentrated in Asia and Africa, this study analyses the association between HRFB and under-five mortality in selected Asian and African countries. Methods: This study used Integrated Public Microdata Series-Demographic and Health Surveys (IPUMS-DHS) data from 32 countries in Sub-Saharan Africa, Middle East, North Africa, and South Asia from 1986 to 2017 (N=1,467,728). Previous evidence hints at four markers of HRFB: women's age at the birth of index child <18 years or >34 years, smaller preceding birth interval (PBI) <24 months, and child's birth order >3. Using logistic regression, we analysed the change in the odds of under-five mortality as a result of i) exposure to HRFB individually, ii) exposure to any single HRFB risk factor, iii) exposure to multiple HRFB risk factors, and iv) exposure to specific combinations of HRFB risk factors. Results: Mother's age at the birth of index child <18 years and preceding birth interval (PBI) <24 months were significant risk factors of under-five mortality, while a child's birth order >3 was a protective factor against under-five mortality. Presence of any single HRFB was associated with 1.067 times higher risk of under-five mortality (OR = 1.067; 95% CI: 1.042 - 1.090; P < 0.001). Presence of multiple HRFBs was associated with 1.392 times higher risk of under-five mortality (OR = 1.392; 95% CI: 1.355 - 1.431; P < 0.001). Some specific combinations of risky fertility behaviour such as younger maternal age (<18 years) and smaller preceding birth interval (PBI <24) significantly increased the odds of under-five mortality.Conclusion: Younger maternal age and small preceding birth interval significantly increase the risk of under-five mortality. This highlights the need for effective legislation to curb child marriages and increased public investment in reproductive healthcare with a focus on higher contraceptive use for an optimal interpregnancy interval.

Neural Tube Defects Decreasing in England

PEDIATRICS ◽  
1982 ◽  
Vol 70 (5) ◽  
pp. 823-823
Author(s):  
J. R. Owens ◽  
F. Harris
Keyword(s):  
New York ◽  
Birth Order ◽  
Neural Tube ◽  
Neural Tube Defects ◽  
Maternal Age ◽  
Recurrence Risk ◽  
Socioeconomic Group ◽  
Similar Decrease

Stein and colleagues1 report a steadily decreasing incidence of myelomeningocele in the Brooklyn area of New York from 1968 to 1979, and which was independent of maternal age, birth order, and socioeconomic group. We have recently demonstrated a similar decrease in incidence of all neural tube defects in the conurbation of Liverpool and Bootle which commenced in the early 1970s, and which was more marked in anencephalus than myelomeningocele.2 The decrease in incidence was not due to smaller affected families as the recurrence risk for the period 1961 to 1969 was similar to that for 1970 to 1979.

Impact of High-Risk Fertility Behaviour on Under-five Mortality in Asia and Africa: Evidence from Demographic and Health Surveys

2020 ◽  
Author(s):  
Rafi Amir-ud-Din ◽  
Lubna Naz ◽  
Anila Rubi ◽  
Muhammad Usman ◽  
Umesh Ghimire
Keyword(s):  
Risk Factors ◽  
High Risk ◽  
Birth Order ◽  
Birth Interval ◽  
Health Surveys ◽  
Maternal Age ◽  
Demographic And Health Surveys ◽  
Index Child ◽  
Under Five ◽  
Fertility Behaviour

Abstract Background: Younger or older maternal age, short inter-pregnancy birth interval, and higher birth order of the child are considered to be high-risk fertility behaviour (HRFB). Under-five mortality being disproportionately concentrated in Asia and Africa, this study analyses the association between HRFB and under-five mortality in selected Asian and African countries.Methods: This study used Integrated Public Microdata Series-Demographic and Health Surveys (IPUMS-DHS) data from 32 countries in Sub-Saharan Africa, Middle East, North Africa, and South Asia from 1986 to 2017 (N=1,467,728). Previous evidence hints at four markers of HRFB: women’s age at the birth of index child <18 years or >34 years, short preceding birth interval (PBI) <24 months, and child’s birth order >3. Using logistic regression, we analysed the change in the odds of under-five mortality as a result of i) exposure to HRFB individually, ii) exposure to any single HRFB risk factor, iii) exposure to multiple HRFB risk factors, and iv) exposure to specific combinations of HRFB risk factors. Results: Mother’s age at the birth of index child <18 years and preceding birth interval (PBI) <24 months were significant risk factors of under-five mortality, while a child’s birth order >3 was a protective factor against under-five mortality. Presence of any single HRFB was associated with 1.067 times higher risk of under-five mortality (OR = 1.067; 95% CI: 1.042 - 1.090; P < 0.001). Presence of multiple HRFBs was associated with 1.392 times higher risk of under-five mortality (OR = 1.392; 95% CI: 1.355 - 1.431; P < 0.001). Some specific combinations of risky fertility behaviour such as younger maternal age (<18 years) and short preceding birth interval (PBI <24) significantly increased the odds of under-five mortality.Conclusion: Younger maternal age and short preceding birth interval significantly increase the risk of under-five mortality. This highlights the need for effective legislation to curb child marriages and increased public investment in reproductive healthcare with a focus on higher contraceptive use for an optimal interpregnancy interval.

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