Correlation of99mTc-HMPAO SPECT with EEG monitoring: prognostic value for outcome of epilepsy surgery in children

Object The object of this study was to evaluate surgical outcome in a select group of patients with medically refractory epilepsy who had undergone corpus callosotomy combined with bilateral subdural electroencephalography (EEG) electrode placement as the initial step in multistage epilepsy surgery. Methods A retrospective chart review of 18 children (ages 3.5–18 years) with medically refractory symptomatic generalized or localization-related epilepsy was undertaken. A corpus callosotomy with subdural bihemispheric EEG electrode placement was performed as the initial step in multistage epilepsy surgery. All of the patients had tonic and atonic seizures; 6 patients also experienced complex partial seizures. All of the patients had frequent generalized epileptiform discharges as well as multifocal independent epileptiform discharges on surface EEG monitoring. Most of the patients (94%) had either normal (44%) MR imaging studies of the brain or bihemispheric abnormalities (50%). One patient had a suspected unilateral lesion (prominent sylvian fissure). Results Of the 18 patients who underwent corpus callosotomy and placement of subdural strips and grids, 12 progressed to further resection based on localizing data obtained during invasive EEG monitoring. The mean patient age was 10.9 years. The duration of invasive monitoring ranged from 3 to 14 days, and the follow-up ranged from 6 to 70 months (mean 35 months). Six (50%) of the 12 patients who had undergone resection had an excellent outcome (Engel Class I or II). There were no permanent neurological deficits or deaths. Conclusions The addition of invasive monitoring for patients undergoing corpus callosotomy for medically refractory epilepsy may lead to the localization of surgically amenable seizure foci, targeted resections, and improved seizure outcomes in a select group of patients typically believed to be candidates for palliative surgery alone.

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The diagnostic utility of intracranial EEG monitoring for epilepsy surgery in children

Epilepsia ◽

10.1111/epi.12983 ◽

2015 ◽

Vol 56 (7) ◽

pp. 1065-1070 ◽

Cited By ~ 13

Author(s):

Paula Brna ◽

Michael Duchowny ◽

Trevor Resnick ◽

Catalina Dunoyer ◽

Sanjiv Bhatia ◽

...

Keyword(s):

Epilepsy Surgery ◽

Diagnostic Utility ◽

Eeg Monitoring ◽

Intracranial Eeg

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Effect of invasive EEG monitoring on cognitive outcome after left temporal lobe epilepsy surgery

Neurology ◽

10.1212/wnl.0000000000002066 ◽

2015 ◽

Vol 85 (17) ◽

pp. 1475-1481 ◽

Cited By ~ 7

Author(s):

Robyn M. Busch ◽

Thomas E. Love ◽

Lara E. Jehi ◽

Lisa Ferguson ◽

Ruta Yardi ◽

...

Keyword(s):

Temporal Lobe Epilepsy ◽

Temporal Lobe ◽

Epilepsy Surgery ◽

Cognitive Outcome ◽

Eeg Monitoring ◽

Left Temporal Lobe

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Prognostic Value of EEG Monitoring After Status Epilepticus: A Prospective Adult Study

Journal of Clinical Neurophysiology ◽

10.1097/00004691-199707000-00005 ◽

1997 ◽

Vol 14 (4) ◽

pp. 326-334 ◽

Cited By ~ 93

Author(s):

Rakesh Jaitly ◽

Joseph A. Sgro ◽

Alan R. Towne ◽

Daijin Ko ◽

Robert J. DeLorenzo

Keyword(s):

Status Epilepticus ◽

Prognostic Value ◽

Eeg Monitoring ◽

Adult Study

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PMD63 - POTENTIAL LONG-TERM SAVINGS RESULTED FROM THE INTRODUCTION OF INVASIVE EEG MONITORING AS A PREOPERATIVE DIAGNOSTIC PROCEDURE IN EPILEPSY SURGERY IN HUNGARY

Value in Health ◽

10.1016/j.jval.2018.09.1512 ◽

2018 ◽

Vol 21 ◽

pp. S253 ◽

Cited By ~ 1

Author(s):

S. Kovács ◽

D. Fabó ◽

M. Tóth ◽

I. Boncz ◽

A. Zemplényi

Keyword(s):

Epilepsy Surgery ◽

Diagnostic Procedure ◽

Eeg Monitoring ◽

Preoperative Diagnostic

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Complications of epilepsy surgery-A systematic review of focal surgical resections and invasive EEG monitoring

Epilepsia ◽

10.1111/epi.12161 ◽

2013 ◽

Vol 54 (5) ◽

pp. 840-847 ◽

Cited By ~ 121

Author(s):

Walter J. Hader ◽

Jose Tellez-Zenteno ◽

Amy Metcalfe ◽

Lisbeth Hernandez-Ronquillo ◽

Samuel Wiebe ◽

...

Keyword(s):

Systematic Review ◽

Epilepsy Surgery ◽

Eeg Monitoring

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Long-Term EEG Monitoring for Difficult Seizure Problems

Journal of Child Neurology ◽

10.1177/0883073894009001101 ◽

1994 ◽

Vol 9 (1_suppl) ◽

pp. S57-S63 ◽

Cited By ~ 6

Author(s):

Jane F. Donat

Keyword(s):

Effective Treatment ◽

Epilepsy Surgery ◽

Eeg Monitoring ◽

Diagnostic Problems ◽

Infancy And Childhood ◽

Clinical Questions ◽

Video Eeg

Long-term electroencephalographic (EEG) monitoring, initially popular in the form of 24-hour video-EEG telemetries developed for the evaluation of patients who were candidates for epilepsy surgery, is now possible in diverse configurations. Studies can be designed to evaluate a variety of diagnostic problems and can be individualized to address specific clinical questions for each patient. A great variety of severe epilepsies present in infancy and childhood with daily seizures, often presenting difficult diagnostic problems. Extending the benefits of long-term EEG monitoring to these patients early in the course of the epileptic process can be expected to result in more accurate diagnoses, more effective treatment, and improved prognoses. Long-term EEG monitoring is needed to improve our understanding of the nosology of infant epilepsy, which is incomplete. ( J Child Neurol 1994;9(Suppl):S57-S63).

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