scholarly journals Diagnostic and prognostic value of noninvasive long-term video-electroencephalographic monitoring in epilepsy surgery: A systematic review and meta-analysis from the E-PILEPSY consortium

Epilepsia ◽  
2018 ◽  
Vol 59 (12) ◽  
pp. 2272-2283 ◽  
Author(s):  
Teia Kobulashvili ◽  
Giorgi Kuchukhidze ◽  
Francesco Brigo ◽  
Georg Zimmermann ◽  
Julia Höfler ◽  
...  
Keyword(s):  
Systematic Review ◽  
Epilepsy Surgery ◽  
Prognostic Value ◽  
Meta Analysis ◽  
Diagnostic And Prognostic Value

scholarly journals Diagnostic and prognostic value of miRNAs in hepatoblastoma: A systematic review with meta-analysis

2021 ◽  
Author(s):  
Bin Wu ◽  
◽  
Lixia Guo ◽  
Kaikai Zhen ◽  
Chao Sun
Keyword(s):  
Systematic Review ◽  
Prognostic Value ◽  
Meta Analysis ◽  
Area Under The Curve ◽  
Prognostic Indicator ◽  
Diagnostic Odds Ratio ◽  
Diagnostic Value ◽  
Likelihood Ratios ◽  
Clinical Value ◽  
Diagnostic And Prognostic Value

Review question / Objective: Background and aim: Increasing evidence has revealed the valuable diagnostic and prognostic applications of dysregulated microRNAs (miRNAs) in hepatoblastoma (HB), the most common hepatic malignancy during childhood. However, these results are inconsistent and remain to be elucidated. In the present study, we aimed to systematically compile up-to-date information regarding the clinical value of miRNAs in HB. Methods: Articles concerning the diagnostic and prognostic value of single miRNAs for HB were searched from databases. The sensitivity (SEN), specificity (SPE), positive and negative likelihood ratios (PLR and NLR), diagnostic odds ratio (DOR), area under the curve (AUC), and hazard ratios (HRs) were separately pooled to explore the diagnostic and prognostic performance of miRNA. Subgroup and meta-regression analyses were further carried out only in the event of heterogeneity. Results: In all, 20 studies, involving 264 HB patients and 206 healthy individuals, met the inclusion criteria in the six included literature articles. For the diagnostic analysis of miRNAs in HB, the pooled SEN and SPE were 0.76 (95% CI: 0.72–0.80) and 0.75 (95% CI: 0.70–0.80), respectively. Moreover, the pooled PLR was 2.79 (95% CI: 2.12–3.66), NLR was 0.34 (95% CI: 0.26–0.45), DOR was 10.24 (95% CI: 6.55–16.00), and AUC was 0.83, indicating that miRNAs had moderate diagnostic value in HB. For the prognostic analysis of miRNAs in HB, the abnormal expressions of miR-21, miR-34a, miR-34b, miR-34c, miR-492, miR-193, miR-222, and miR-224 in patients were confirmed to be associated with a worse prognosis. The pooled HR was 1.74 (95% CI: 1.20–2.29) for overall survival (OS) and 1.74 (95% CI: 1.31–2.18) for event-free survival (EFS), suggesting its potential as a prognostic indicator for HB. Conclusion: To the best of our knowledge, this is the first comprehensive systematic review and meta-analysis that examines the diagnostic and prognostic role of dysregulated miRNAs in HB patients. The combined meta-analysis results supported the previous individual finds that miRNAs might provide a new, noninvasive method for the diagnostic and prognostic analyses ofHB.

Diagnostic and prognostic value of circulating miR-21 for cancer: A systematic review and meta-analysis

Gene ◽  
2014 ◽  
Vol 533 (1) ◽  
pp. 389-397 ◽  
Author(s):  
Yang Wang ◽  
Xujie Gao ◽  
Feng Wei ◽  
Xinwei Zhang ◽  
Jinpu Yu ◽  
...  
Keyword(s):  
Systematic Review ◽  
Prognostic Value ◽  
Meta Analysis ◽  
Diagnostic And Prognostic Value

scholarly journals Diagnostic and prognostic value of circular RNA CDR1as/ciRS‐7 for solid tumours: A systematic review and meta‐analysis

2020 ◽  
Vol 24 (17) ◽  
pp. 9507-9517 ◽  
Author(s):  
Yutian Zou ◽  
Shaoquan Zheng ◽  
Xinpei Deng ◽  
Anli Yang ◽  
Yanan Kong ◽  
...  
Keyword(s):  
Systematic Review ◽  
Prognostic Value ◽  
Meta Analysis ◽  
Circular Rna ◽  
Solid Tumours ◽  
Diagnostic And Prognostic Value

Prognostic Value of 24-H ABPM in Acute Ischemic Stroke for Short-, Medium-, and Long-Term Outcome: A Systematic Review and Meta-Analysis

2015 ◽  
Vol 10 (7) ◽  
pp. 1000-1007 ◽  
Author(s):  
Nikolaos Kakaletsis ◽  
George Ntaios ◽  
Haralampos Milionis ◽  
Anna-Bettina Haidich ◽  
Konstantinos Makaritsis ◽  
...  
Keyword(s):  
Systematic Review ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Prognostic Value ◽  
Meta Analysis ◽  
Term Outcome ◽  
Long Term Outcome

Diagnostic and prognostic value of miRNAs on salivary gland tumors: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Erison Santana Dos Santos ◽  
Ana Gabriela Costa Normando ◽  
João Figueira Scarini ◽  
Lívia Ramalho Crescencio ◽  
Reydson Alcides de Lima-Souza ◽  
...  
Keyword(s):  
Systematic Review ◽  
Salivary Gland ◽  
Prognostic Value ◽  
Meta Analysis ◽  
Salivary Gland Tumors ◽  
Diagnostic And Prognostic Value

scholarly journals Diagnostic and prognostic value of carcinoembryonic antigen in pancreatic cancer: a systematic review and meta-analysis

2017 ◽  
Vol Volume 10 ◽  
pp. 4591-4598 ◽  
Author(s):  
Qingcai Meng ◽  
Si Shi ◽  
Chen Liang ◽  
Dingkong Liang ◽  
Wenyan Xu ◽  
...  
Keyword(s):  
Systematic Review ◽  
Pancreatic Cancer ◽  
Carcinoembryonic Antigen ◽  
Prognostic Value ◽  
Meta Analysis ◽  
Diagnostic And Prognostic Value
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