Influence of prenatal exposure to cimetidine and alcohol on selected morphological parameters of sexual differentiation: A preliminary report

1987 ◽  
Vol 9 (1) ◽  
pp. 23-26 ◽  
Author(s):  
Robert F. McGivern
2008 ◽  
Vol 84 ◽  
pp. S52
Author(s):  
Bilic Iva ◽  
Igor Prpic ◽  
Robert Krajina ◽  
Inge Karavida ◽  
Vesna Mahulja-Stamenkovic ◽  
...  

1995 ◽  
Vol 208 (1) ◽  
pp. 60-66 ◽  
Author(s):  
J. R. Levy ◽  
K. A. Faber ◽  
L. Ayyash ◽  
C. L. Hughes

1967 ◽  
Vol 31 ◽  
pp. 177-179
Author(s):  
W. W. Shane

In the course of several 21-cm observing programmes being carried out by the Leiden Observatory with the 25-meter telescope at Dwingeloo, a fairly complete, though inhomogeneous, survey of the regionl11= 0° to 66° at low galactic latitudes is becoming available. The essential data on this survey are presented in Table 1. Oort (1967) has given a preliminary report on the first and third investigations. The third is discussed briefly by Kerr in his introductory lecture on the galactic centre region (Paper 42). Burton (1966) has published provisional results of the fifth investigation, and I have discussed the sixth in Paper 19. All of the observations listed in the table have been completed, but we plan to extend investigation 3 to a much finer grid of positions.


Author(s):  
Walter J. Sapp ◽  
D.E. Philpott ◽  
C.S. Williams ◽  
K. Kato ◽  
J. Stevenson ◽  
...  

Space flight, with its unique environmental constraints such as immobilization, decreased and increased pressures, and radiation, is known to affect testicular morphology and spermatogenesis. Selye, summarized the manifestations of physiological response to nonspecific stress and he pointed out that atrophy of the gonads always occurred. Reports of data collected from two dogs flown in space for 22 days (Cosmos 110) indicate that there was an increase of 30 to 70% atypical spermatozoa when compared to ground based controls. Seventy-five days after the flight the abnormalities had decreased to the high normal value of 30% and mating of these dogs after this period produced normal offspring, suggesting complete recovery. Effects of immobilization and increased gravity were investigated by spinning rats and mice at 2x g for 8-9 weeks. A decrease in testicular weight was noted in spun animals when compared to controls. Immobilization has been show to cause arrest of spermatogenesis in Macaca meminstrins.


Author(s):  
C. Uphoff ◽  
C. Nyquist-Battie

Fetal Alcohol Syndrone (FAS) is a syndrome with characteristic abnormalities resulting from prenatal exposure to ethanol. In many children with FAS syndrome gross pathological changes in the heart are seen with septal defects the most prevalent abnormality recorded. Few studies in animal models have been performed on the effects of ethanol on heart development. In our laboratory, it has been observed that prenatal ethanol exposure of Swiss albino mice results in abnormal cardiac muscle ultrastructure when mice were examined at birth and compared to pairfed and normal controls. Fig. 1 is an example of the changes that are seen in the ethanol-exposed animals. These changes include enlarged mitochondria with loss of inner mitochondrial membrane integrity and loss of myofibrils. Morphometric analysis substantiated the presence of these alterations from normal cardiac ultrastructure. The present work was undertaken to determine if the pathological changes seen in the newborn mice prenatally exposed to ethanol could be reversed with age and abstinence.


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