What is the role of the insulin receptor tyrosine kinase?

Trends in Biochemical Sciences ◽

10.1016/0968-0004(88)90170-3 ◽

1988 ◽

Vol 13 (10) ◽

pp. 367-368 ◽

Author(s):

Joseph Espinal

Keyword(s):

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Insulin Receptor Tyrosine Kinase

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Role of divalent metals in the kinetic mechanism of insulin receptor tyrosine kinase

Archives of Biochemistry and Biophysics ◽

10.1016/0003-9861(88)90349-9 ◽

1988 ◽

Vol 261 (2) ◽

pp. 336-345 ◽

Author(s):

Pasquale P. Vicario ◽

Richard Saperstein ◽

Alfred Bennun

Keyword(s):

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Kinetic Mechanism ◽

Insulin Receptor Tyrosine Kinase ◽

Divalent Metals

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Role of divalent metals in the activation and regulation of insulin receptor tyrosine kinase

10.1016/0303-2647(88)90050-0 ◽

1988 ◽

Vol 22 (1) ◽

pp. 55-66 ◽

Author(s):

Pasquale P. Vicario ◽

Richard Saperstein ◽

Alfred Bennun

Keyword(s):

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Insulin Receptor Tyrosine Kinase ◽

Divalent Metals

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Insulin receptor tyrosine kinase activity is reduced in type-2 (non-insulin-dependent) diabetes but not in obesity

Acta Endocrinologica ◽

10.1530/acta.0.114s183 ◽

1987 ◽

Vol 116 (3_Suppl) ◽

pp. S183

Author(s):

H.H. KLEIN ◽

G.R. FREIDENBERG ◽

R.R. HENRY ◽

J.M. OLEFSKY

Keyword(s):

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Kinase Activity ◽

Insulin Dependent Diabetes ◽

Tyrosine Kinase Activity ◽

Insulin Receptor Tyrosine Kinase ◽

Insulin Dependent

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Prevention by protein kinase C inhibitors of glucose-induced insulin-receptor tyrosine kinase resistance in rat fat cells

Diabetes ◽

10.2337/diabetes.40.11.1440 ◽

1991 ◽

Vol 40 (11) ◽

pp. 1440-1448 ◽

Author(s):

H. K. Muller ◽

M. Kellerer ◽

B. Ermel ◽

A. Muhlhofer ◽

B. Obermaier-Kusser ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Fat Cells ◽

Insulin Receptor Tyrosine Kinase ◽

Protein Kinase C Inhibitors ◽

Kinase C ◽

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Effect of streptozocin-induced diabetes on insulin-receptor tyrosine kinase activity in obese Zucker rats

Diabetes ◽

10.2337/diabetes.39.5.619 ◽

1990 ◽

Vol 39 (5) ◽

pp. 619-625 ◽

Author(s):

L. J. Slieker ◽

E. F. Roberts ◽

W. N. Shaw ◽

W. T. Johnson

Keyword(s):

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Kinase Activity ◽

Zucker Rats ◽

Tyrosine Kinase Activity ◽

Insulin Receptor Tyrosine Kinase ◽

Obese Zucker Rats

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pp120/ecto-ATPase, an endogenous substrate of the insulin receptor tyrosine kinase, is expressed as two variably spliced isoforms.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)54060-6 ◽

1993 ◽

Vol 268 (2) ◽

pp. 1201-1206 ◽

Author(s):

S.M. Najjar ◽

D. Accili ◽

N. Philippe ◽

J. Jernberg ◽

R. Margolis ◽

...

Keyword(s):

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Insulin Receptor Tyrosine Kinase ◽

Endogenous Substrate

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Substrate Phosphorylation Catalyzed by the Insulin Receptor Tyrosine Kinase

Journal of Biological Chemistry ◽

10.1016/s0021-9258(20)88221-0 ◽

1989 ◽

Vol 264 (36) ◽

pp. 21557-21572

Author(s):

J R Flores-Riveros ◽

E Sibley ◽

T Kastelic ◽

M D Lane

Keyword(s):

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Insulin Receptor Tyrosine Kinase ◽

Substrate Phosphorylation

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Monoclonal Antibodies Mimic Insulin Activation of Ribosomal Protein S6 Kinase without Activation of Insulin Receptor Tyrosine Kinase

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)47250-5 ◽

1989 ◽

Vol 264 (32) ◽

pp. 18951-18959 ◽

Author(s):

C K Sung ◽

B A Maddux ◽

D M Hawley ◽

I D Goldfine

Keyword(s):

Monoclonal Antibodies ◽

Tyrosine Kinase ◽

Ribosomal Protein ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

S6 Kinase ◽

Insulin Receptor Tyrosine Kinase ◽

Ribosomal Protein S6 ◽

Ribosomal Protein S6 Kinase

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A specific type of ganglioside as a modulator of insulin-dependent cell growth and insulin receptor tyrosine kinase activity

Journal of Biological Chemistry ◽

10.1016/s0021-9258(20)64355-1 ◽

1991 ◽

Vol 266 (7) ◽

pp. 4531-4537

Author(s):

H Nojiri ◽

M Stroud ◽

S Hakomori

Keyword(s):

Cell Growth ◽

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Kinase Activity ◽

Tyrosine Kinase Activity ◽

Insulin Receptor Tyrosine Kinase ◽

Dependent Cell ◽

Insulin Dependent

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Specific Inhibition of Insulin-Like Growth Factor-1 and Insulin Receptor Tyrosine Kinase Activity and Biological Function by Tyrphostins

Endocrinology ◽

10.1210/endo.138.4.5092 ◽

1997 ◽

Vol 138 (4) ◽

pp. 1427-1433 ◽

Author(s):

Marcelina Párrizas ◽

Aviv Gazit ◽

Alexander Levitzki ◽

Efrat Wertheimer ◽

Derek LeRoith

Keyword(s):

Growth Factor ◽

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Kinase Activity ◽

Biological Function ◽

Specific Inhibition ◽

Insulin Like Growth Factor ◽

Tyrosine Kinase Activity ◽

Insulin Receptor Tyrosine Kinase

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