Ovine fetal glucocorticoid treatment alters premature newborn renal responses to intravascular volume expansion

1995 ◽  
Vol 2 (2) ◽  
pp. 341 ◽  
Author(s):  
M ERVIN
Keyword(s):  
Volume Expansion ◽  
Intravascular Volume ◽  
Glucocorticoid Treatment ◽  
Premature Newborn ◽  
Ovine Fetal ◽  
Renal Responses

Isohemic blood volume expansion in normal and areflexive dogs

1976 ◽  
Vol 231 (1) ◽  
pp. 104-111 ◽  
Author(s):  
A Cevese ◽  
AC Guyton
Keyword(s):  
Arterial Pressure ◽  
Volume Expansion ◽  
Autologous Blood ◽  
Minor Role ◽  
Intravascular Volume ◽  
Natriuretic Hormone ◽  
Circulatory Response ◽  
Blood Volume Expansion ◽  
Mechanical Factors ◽  
Renal Responses

The hemodynamic and renal responses to rapid intravascular volume expansion (VE) were studied in normal and areflexive dogs. "Isohemic" expansion was performed by infusing autologous blood (averaging 453 ml) thoroughly mixed with the circulating blood. In areflexive dogs cardiac output and arterial pressure doubled immediately after VE and fell back to control within 70 min; in normal dogs the circulatory response was less than one-third as great, but arterial pressure failed to return to control within 120 min. In the areflexive dogs, water, electrolyte, and total osmolar urinary output rose three- to fivefold after VE and declined thereafter, roughly following arterial pressure. In normal dogs the urine flow increased 40% immediately and rose further up to 70% in 60 min. No evidence for a natriuretic hormone was seen. It is concluded that mechanical factors are mainly responsible for the increased excretion of water and solutes after VE. Direct nervous reflexes to the kidney seemed to play a quantitatively minor role in the renal response.

scholarly journals Short-term Antenatal Glucocorticoid Exposure Alters Preterm Newborn Lamb Renal Responses to Intravascular Volume Expansion. • 823

1997 ◽  
Vol 41 ◽  
pp. 140-140
Author(s):  
Lynne M. Berry ◽  
Gore Ervin ◽  
Celso Rebello ◽  
Norihisa Wada ◽  
Machiko Ikegami ◽  
...  
Keyword(s):  
Volume Expansion ◽  
Preterm Newborn ◽  
Intravascular Volume ◽  
Short Term ◽  
Newborn Lamb ◽  
Renal Responses

Atrial natriuretic peptide and blunted renal responses to volume expansion in rats with Heymann nephritis

1993 ◽  
Vol 11 (5) ◽  
pp. S218???S219 ◽  
Author(s):  
Jean-Pierre Valentin ◽  
Wei-Zhong Ying ◽  
Leonardo A. Sechi ◽  
Michael H. Humphreys
Keyword(s):  
Atrial Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Volume Expansion ◽  
Heymann Nephritis ◽  
Renal Responses ◽  
Atrial Natriuretic

Neural influences on renal responses to acute volume expansion in rats with heart failure

1996 ◽  
Vol 271 (4) ◽  
pp. H1441-H1448 ◽  
Author(s):  
K. P. Patel ◽  
P. L. Zhang ◽  
P. K. Carmines
Keyword(s):  
Heart Failure ◽  
Atrial Natriuretic Factor ◽  
Volume Expansion ◽  
Renal Nerve ◽  
Natriuretic Factor ◽  
Renal Nerve Activity ◽  
Neural Influences ◽  
Renal Responses ◽  
Renal Sympathetic ◽  
Atrial Natriuretic

Experiments were performed to test the postulate that neural influences underlie the suppressed excretory response to acute volume expansion (VE) typically observed 3-4 wk after myocardial infarction to induce chronic heart failure (CHF). Responses to VE were assessed in innervated (intact) and denervated (DNX) kidneys of anesthetized CHF rats and sham-operated controls. CHF rats exhibited blunted natriuretic responses to VE in both intact kidneys (35% of sham response) and DNX kidneys (55% of sham DNX response). CHF rats also displayed suppressed excretory responses to atrial natriuretic factor (0.25 microgram.kg-1.min-1 iv) in both intact kidneys (74% of sham response) and DNX kidneys (63% of sham DNX response). Additional experiments confirmed that the compliance of the venoatrial junction did not differ between sham rats (52 +/- 2 mmHg/microliter) and CHF rats (54-2 mmHg/microliter). The observations support the contention that both tonic renal sympathetic renal nerve activity and suppressed renal atrial natriuretic factor responsiveness likely contribute to the blunted excretory response to VE during CHF.

Intravascular Volume Expansion as Therapeutic Approach to the Underfill State of Preeclampsia

1989 ◽  
pp. 111-113
Author(s):  
P. Stratta ◽  
C. Canavese ◽  
L. Gurioli ◽  
M. Porcu ◽  
M. Dogliani ◽  
...  
Keyword(s):  
Therapeutic Approach ◽  
Volume Expansion ◽  
Intravascular Volume
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