Identification and Characterization of Neuromedin B Receptors in Rat Central Nervous System

1991 ◽  
pp. 426-441 ◽  
Author(s):  
Ellen E. Ladenheim ◽  
Timothy H. Moran ◽  
Robert T. Jensen
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Neuromedin B ◽  
Identification And Characterization

Linfoistiocitosi eritrofagocitica

2003 ◽  
Vol 16 (3) ◽  
pp. 365-372 ◽  
Author(s):  
F. Caranci ◽  
A. D'Amico ◽  
F. Briganti ◽  
R. Migliorati ◽  
C. De Fusco ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Bone Marrow ◽  
Nervous System ◽  
White Matter ◽  
White Matter Abnormalities ◽  
Diffuse White Matter ◽  
Multisystem Involvement ◽  
Identification And Characterization

Erithrophagocytic lymphohistiocytosis is a rare disease characterized by exaggerated histiocytic proliferation and activation12 and multisystem involvement including visceral organs, lymph nodes, bone marrow and central nervous system4. Magnetic Resonance (MR) examination was performed in 10 patients with previously diagnosed Erithrophagocytic lymphohistiocytosis. This study was aimed at assessing MR accuracy in the identification and characterization of central nervous system lesions. MR findings show a good correlation with areas of parenchymal and meningeal lymphohistiocytic infiltration5, demonstrating diffuse white matter abnormalities in the early stages and necrotic areas with parenchymal volume loss as terminal findings4. In addition, MR allows the follow-up after chemotherapy and bone marrow transplantation2,3. Although rare, EL should be differentiated from other pediatric patchy white matter abnormalities5.

scholarly journals Identification and characterization of nCLP2, a novel C1q family protein expressed in the central nervous system

2009 ◽  
Vol 147 (4) ◽  
pp. 565-579 ◽  
Author(s):  
C. Shimono ◽  
R. i. Manabe ◽  
T. Yamada ◽  
S. Fukuda ◽  
J. Kawai ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Family Protein ◽  
The Central Nervous System ◽  
Identification And Characterization

Identification and characterization of ε-sarcoglycans in the central nervous system

2004 ◽  
Vol 125 (1-2) ◽  
pp. 1-12 ◽  
Author(s):  
Akiyo Nishiyama ◽  
Takeshi Endo ◽  
Shin'ichi Takeda ◽  
Michihiro Imamura
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
The Central Nervous System ◽  
Identification And Characterization

scholarly journals Molecular Modeling of Histamine Receptors—Recent Advances in Drug Discovery

Molecules ◽  
2021 ◽  
Vol 26 (6) ◽  
pp. 1778
Author(s):  
Pakhuri Mehta ◽  
Przemysław Miszta ◽  
Sławomir Filipek
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Molecular Modeling ◽  
Molecular Targets ◽  
Histamine Receptors ◽  
Experimental Characterization ◽  
Complex Disorders ◽  
Theoretical Investigations ◽  
Recent Developments

The recent developments of fast reliable docking, virtual screening and other algorithms gave rise to discovery of many novel ligands of histamine receptors that could be used for treatment of allergic inflammatory disorders, central nervous system pathologies, pain, cancer and obesity. Furthermore, the pharmacological profiles of ligands clearly indicate that these receptors may be considered as targets not only for selective but also for multi-target drugs that could be used for treatment of complex disorders such as Alzheimer’s disease. Therefore, analysis of protein-ligand recognition in the binding site of histamine receptors and also other molecular targets has become a valuable tool in drug design toolkit. This review covers the period 2014–2020 in the field of theoretical investigations of histamine receptors mostly based on molecular modeling as well as the experimental characterization of novel ligands of these receptors.

scholarly journals Immunological and Molecular Characterization of Goα-like Proteins in the Drosophila Central Nervous System

1989 ◽  
Vol 264 (31) ◽  
pp. 18552-18560 ◽  
Author(s):  
N C Thambi ◽  
F Quan ◽  
W J Wolfgang ◽  
A Spiegel ◽  
M Forte
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Molecular Characterization
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