Cyanide Toxicity and its Treatment

Motor and memory function in rat models of cyanide toxicity and vascular occlusion induced ischemic injury

Pathophysiology ◽

10.1016/j.pathophys.2014.07.002 ◽

2014 ◽

Vol 21 (3) ◽

pp. 191-198 ◽

Cited By ~ 3

Author(s):

Olalekan Michael Ogundele ◽

Philip Adeyemi Adeniyi ◽

Duyilemi Chris Ajonijebu ◽

Amin Abdulbasit ◽

Ansa Emmanuel Cobham ◽

...

Keyword(s):

Memory Function ◽

Vascular Occlusion ◽

Ischemic Injury ◽

Rat Models ◽

Cyanide Toxicity

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Improving the cyanide toxicity tolerance of anaerobic reactor: Microbial interactions and toxin reduction

Journal of Hazardous Materials ◽

10.1016/j.jhazmat.2016.04.028 ◽

2016 ◽

Vol 315 ◽

pp. 52-60 ◽

Cited By ~ 10

Author(s):

Pragya Gupta ◽

S.Z. Ahammad ◽

T.R. Sreekrishnan

Keyword(s):

Microbial Interactions ◽

Anaerobic Reactor ◽

Cyanide Toxicity

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432 Intravenous Hydroxocobalamin versus Intraosseous Hydroxocobalamin in the Treatment of Acute, Severe Cyanide Toxicity in a Validated Swine Model

Annals of Emergency Medicine ◽

10.1016/j.annemergmed.2011.06.466 ◽

2011 ◽

Vol 58 (4) ◽

pp. S324

Author(s):

V.S. Bebarta ◽

J. Lairet ◽

R. Pitotti ◽

P. Dixon ◽

S. Valtier ◽

...

Keyword(s):

Swine Model ◽

Cyanide Toxicity

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Modelling anaerobic digestion acclimatisation to a biodegradable toxicant: application to cyanide

Water Science & Technology ◽

10.2166/wst.2006.534 ◽

2006 ◽

Vol 54 (4) ◽

pp. 129-137 ◽

Cited By ~ 11

Author(s):

U. Zaher ◽

M.S. Moussa ◽

I.N. Widyatmika ◽

P. van Der Steen ◽

H.J. Gijzen ◽

...

Keyword(s):

Anaerobic Digestion ◽

Inorganic Nitrogen ◽

Degradation Pathway ◽

Anaerobic Sludge ◽

Buffer Solution ◽

Cyanide Toxicity ◽

Cyanide Degradation ◽

Hydrogenotrophic Methanogens ◽

Cassava Wastewater ◽

Equilibrium Calculations

The observed acclimatisation to biodegradable toxicants in anaerobic cassava wastewater treatment is explained by modelling anaerobic cyanide degradation. A complete degradation pathway is proposed for cyanide. Cyanide degradation is modelled as enzymatic hydrolysis to formate and ammonia. Ammonia is added to the inorganic nitrogen content of the digester while formate is degraded by the hydrogenotrophic methanogens. Cyanide irreversible enzyme inhibition is modelled as an inhibition factor to acetate uptake processes. Cyanide irreversible toxicity is modelled as a decay factor to the acetate degraders. Cyanide as well as added phosphorus buffer solution were considered in the chemical equilibrium calculations of pH. The observed reversible effect after acclimatisation of sludge is modelled by a population shift between two aceticlastic methanogens that have different tolerance to cyanide toxicity. The proposed pathway is added to the IWA Anaerobic Digestion Model no.1 (ADM1). The ADM1 model with the designed extension is validated by an experiment using three lab-scale upflow anaerobic sludge bed reactors which were exposed to different cyanide loadings.

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