Characterization of charge variants of a monoclonal antibody using weak anion exchange chromatography at subunit levels

Exchange Chromatography ◽

Charge Variants ◽

Characterization of Recombinant Monoclonal Antibody Charge Variants Using OFFGEL Fractionation, Weak Anion Exchange Chromatography, and Mass Spectrometry

Analytical Chemistry ◽

10.1021/acs.analchem.5b01452 ◽

2015 ◽

Vol 87 (12) ◽

pp. 6204-6211 ◽

Cited By ~ 28

Author(s):

Alyssa Neill ◽

Christine Nowak ◽

Rekha Patel ◽

Gomathinayagam Ponniah ◽

Nidia Gonzalez ◽

...

Keyword(s):

Mass Spectrometry ◽

Monoclonal Antibody ◽

Anion Exchange ◽

Exchange Chromatography ◽

Recombinant Monoclonal Antibody ◽

Charge Variants ◽

Characterization of Heparin Impurities with HPLC-NMR Using Weak Anion Exchange Chromatography

Analytical Chemistry ◽

10.1021/ac901812y ◽

2009 ◽

Vol 81 (24) ◽

pp. 10116-10123 ◽

Cited By ~ 25

Author(s):

John F. K. Limtiaco ◽

Christopher J. Jones ◽

Cynthia K. Larive

Keyword(s):

Anion Exchange ◽

Exchange Chromatography ◽

Two-dimensional (weak anion exchange chromatography-gel electrophoresis) separations coupling to inductively coupled plasma mass spectrometry strategy for analysis of metalloproteins

Talanta ◽

10.1016/j.talanta.2018.03.037 ◽

2018 ◽

Vol 184 ◽

pp. 404-410 ◽

Cited By ~ 10

Author(s):

Xueting Yan ◽

Bin He ◽

Dingyi Wang ◽

Ligang Hu ◽

Lihong Liu ◽

...

Keyword(s):

Mass Spectrometry ◽

Anion Exchange ◽

Gel Electrophoresis ◽

Inductively Coupled Plasma ◽

Exchange Chromatography ◽

Two Dimensional ◽

Inductively Coupled ◽

Plasma Mass Spectrometry ◽

Author response for "The prevention of an anomalous chromatographic behavior and the resulting successful removal of viruses from monoclonal antibody with an asymmetric charge distribution by using a membrane adsorber in highly efficient, anion‐exchange chromatography in flow‐through mode"

10.1002/btpr.2955/v2/response1 ◽

2019 ◽

Author(s):

Yumiko Masuda ◽

Yuka Ogino ◽

Kozo Yamaichi ◽

Yusuke Takahashi ◽

Koichi Nonaka ◽

...

Keyword(s):

Monoclonal Antibody ◽

Anion Exchange ◽

Charge Distribution ◽

Exchange Chromatography ◽

Author Response ◽

Chromatographic Behavior ◽

Successful Removal ◽

Flow Through ◽

Membrane Adsorber

Decision letter for "The prevention of an anomalous chromatographic behavior and the resulting successful removal of viruses from monoclonal antibody with an asymmetric charge distribution by using a membrane adsorber in highly efficient, anion‐exchange chromatography in flow‐through mode"

10.1002/btpr.2955/v2/decision1 ◽

2019 ◽

Keyword(s):

Monoclonal Antibody ◽

Anion Exchange ◽

Charge Distribution ◽

Exchange Chromatography ◽

Chromatographic Behavior ◽

Highly Efficient ◽

Successful Removal ◽

Flow Through ◽

Membrane Adsorber

Biological Characterization of a Pituitary Monkey Lutropin Preparation after Chromatofocusing or after High Performance Anion Exchange Chromatography

Journal of Liquid Chromatography ◽

10.1080/01483918808067171 ◽

1988 ◽

Vol 11 (6) ◽

pp. 1261-1271

Author(s):

Per Hallin ◽

Shafiq A. Khan

Keyword(s):

Anion Exchange ◽

High Performance ◽

Exchange Chromatography ◽

Biological Characterization

Selectivity issues in targeted metabolomics: Separation of phosphorylated carbohydrate isomers by mixed-mode hydrophilic interaction/weak anion exchange chromatography

Journal of Separation Science ◽

10.1002/jssc.201000412 ◽

2010 ◽

Vol 33 (21) ◽

pp. 3273-3282 ◽

Cited By ~ 62

Author(s):

Helmut Hinterwirth ◽

Michael Lämmerhofer ◽

Beatrix Preinerstorfer ◽

Andrea Gargano ◽

Roland Reischl ◽

...

Keyword(s):

Anion Exchange ◽

Mixed Mode ◽

Exchange Chromatography ◽

Targeted Metabolomics ◽

Hydrophilic Interaction ◽

Characterization of highly purified, inactivated HIV-1 particles isolated by anion exchange chromatography

Vaccine ◽

10.1016/s0264-410x(97)00196-5 ◽

1998 ◽

Vol 16 (2-3) ◽

pp. 119-129 ◽

Cited By ~ 35

Author(s):

Steven P. Richieri ◽

Richard Bartholomew ◽

Roland C. Aloia ◽

Jay Savary ◽

Richard Gore ◽

...

Keyword(s):

Anion Exchange ◽

Exchange Chromatography ◽

Hiv 1

Monoclonal antibody purification by medium-performance anion-exchange chromatography

Trends in Genetics ◽

10.1016/0168-9525(87)90189-2 ◽

1987 ◽

Vol 3 ◽

pp. 89

Keyword(s):

Monoclonal Antibody ◽

Anion Exchange ◽

Exchange Chromatography ◽

Antibody Purification

Synthesis and Characterization of High-Affinity, Low-Molecular-Mass Displacers for Anion-Exchange Chromatography

Industrial & Engineering Chemistry Research ◽

10.1021/ie020255g ◽

2002 ◽

Vol 41 (25) ◽

pp. 6482-6492 ◽

Cited By ~ 18

Author(s):

Nihal Tugcu ◽

Sun K. Park ◽

J. A. Moore ◽

Steven M. Cramer

Keyword(s):

Molecular Mass ◽

Anion Exchange ◽

Exchange Chromatography ◽

Synthesis And Characterization ◽

High Affinity