Dual-color graphene quantum dots and carbon nanoparticles biosensing platform combined with Exonuclease III-assisted signal amplification for simultaneous detection of multiple DNA targets

2021 ◽  
Vol 1154 ◽  
pp. 338346
Author(s):  
Song Wang ◽  
Guangjie Kang ◽  
Fangli Cui ◽  
Yingwei Zhang
2015 ◽  
Vol 7 (20) ◽  
pp. 8877-8881 ◽  
Author(s):  
Chengfei Zhao ◽  
Zong'en Liu ◽  
Wentan Xu ◽  
Min Chen ◽  
Shaohuang Weng ◽  
...  

In this present work, graphene quantum dots (GQDs) were handily prepared with citric acid by the pyrolysis method and used to fabricate an electrochemical sensor for the simultaneous determination of acetaminophen (AC) and ascorbic acid (AA) in compound preparation.


Author(s):  
Peyman Mohammadzadeh Jahani

The electrochemical sensor was fabricated for the simultaneous determination of levodopa and cabergoline using carbon paste electrode (CPE) modified with graphene quantum dots (GQD), 2-chlorobenzoyl ferrocene (2CBF) and ionic liquid (IL). Then, the electrochemical behavior of levodopa alone and simultaneously with cabergoline at the surface of GQDs/2CBF/IL/CPE was investigated in phosphate buffer solution (PBS). Under optimal PBS, pH=7 condition, oxidation peak current has been found proportional to levodopa concentration in the range between 0.07 μM and 500.0 μM, with the limit of detection (LOD) of 0.02 μM (S/N=3). Outputs showed that at GQDs/2CBF/IL/CPE surface, the levodopa and cabergoline oxidation peaks are separated by the potential difference of 200 mV. In addition, it was found that this modified electrode possesses acceptable sensitivity, selectivity, stability and repeatability. All these properties were sufficient to allow simultaneous detection of levodopa and cabergoline in real samples at the surface of GQDs/2CBF/IL/CPE. This was supported by the successful application of this electro­chemical sensor electrode for the determination of levodopa and cabergoline in urine, serum, and cabergoline tablets.


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