Noninvasive detection and analysis of human globulin based on dynamic spectrum

2021 ◽  
pp. 339298
Author(s):  
Gang Li ◽  
Dan Wang ◽  
Liu Guozhong ◽  
Wang Xiaofei ◽  
Kang Wang ◽  
...  
2020 ◽  
Vol 48 (5) ◽  
pp. 2295-2305
Author(s):  
Jiawei Zhang ◽  
Dandan Li ◽  
Rui Zhang ◽  
Peng Gao ◽  
Rongxue Peng ◽  
...  

The role of miR-21 in the pathogenesis of various liver diseases, together with the possibility of detecting microRNA in the circulation, makes miR-21 a potential biomarker for noninvasive detection. In this review, we summarize the potential utility of extracellular miR-21 in the clinical management of hepatic disease patients and compared it with the current clinical practice. MiR-21 shows screening and prognostic value for liver cancer. In liver cirrhosis, miR-21 may serve as a biomarker for the differentiating diagnosis and prognosis. MiR-21 is also a potential biomarker for the severity of hepatitis. We elucidate the disease condition under which miR-21 testing can reach the expected performance. Though miR-21 is a key regulator of liver diseases, microRNAs coordinate with each other in the complex regulatory network. As a result, the performance of miR-21 is better when combined with other microRNAs or classical biomarkers under certain clinical circumstances.


2017 ◽  
Vol E100.B (2) ◽  
pp. 390-399
Author(s):  
Katsuya NAKAHIRA ◽  
Jun MASHINO ◽  
Jun-ichi ABE ◽  
Daisuke MURAYAMA ◽  
Tadao NAKAGAWA ◽  
...  

2009 ◽  
Vol E92-B (12) ◽  
pp. 3581-3585
Author(s):  
Hyoungsuk JEON ◽  
Sooyeol IM ◽  
Youmin KIM ◽  
Seunghee KIM ◽  
Jinup KIM ◽  
...  

2012 ◽  
Vol 35 (3) ◽  
pp. 446-453 ◽  
Author(s):  
Yu-Ming GE ◽  
Yi SUN ◽  
Hai JIANG ◽  
Jun LI ◽  
Zhong-Cheng LI

2014 ◽  
Author(s):  
Sheng-Kwei Song ◽  
William M. Spees ◽  
Peng Sun ◽  
Yong Wang ◽  
Anne Cross

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