Concurrent Plasmodium infection, anemia and their correlates among newly diagnosed people living with HIV/AIDS in Northern Ethiopia

Abstract Background Ethiopia is striving to achieve a goal of “zero human immune deficiency virus/acquired immune deficiency syndrome (HIV/AIDS)-related deaths.” However, little has been documented on the factors that hamper the progress towards achieving this goal. Therefore, the ultimate aim of this study was to determine predictors of mortality among adult people living with HIV/AIDS on antiretroviral therapy (ART). Methods A retrospective follow-up study was employed on all adult HIV/AIDS patients who started ART between January 1 and December 30, 2010, at Suhul Hospital, Tigrai Region, Northern Ethiopia. Data were collected by trained fourth-year Public Health students using a checklist. Finally, the collected data were entered into SPSS version 16. Then after, Kaplan-Meier curves were used to estimate survival probability, the log-rank test was used for comparing the survival status, and Cox proportional hazards model were applied to determine predictors of mortality. Results The median follow-up period was 51 months (ranging between 1 and 60 months, inter-quartile range (IQR) = 14 months). At the end of follow-up, 37 (12.5%) patients were dead. The majority of these cumulative deaths, 19 (51.4%) and 29 (78.4%), occurred within 3 and 4 years of ART initiation respectively. Consuming alcohol (adjusted hazard ratio (AHR) = 2.23, 95% CI = 1.15, 4.32), low body weight (AHR = 2.38, 95% CI = 1.03, 5.54), presence of opportunistic infections (AHR = 2.18, 95% CI = 1.09, 4.37), advanced WHO clinical stage (AHR = 2.75, 95% CI = 1.36, 5.58), and not receiving isoniazid prophylactic therapy (AHR = 3.00, 95% CI = 1.33, 6.74) were found to be independent predictors of mortality. Conclusion The overall mortality was very high. Baseline alcohol consumption, low body weight, advanced WHO clinical stage, the presence of opportunistic infections, and not receiving isoniazid prophylactic therapy were predictors of mortality. Strengthening behavioral and nutritional counseling with close clinical follow-up shall be given much more emphasis in the ART care and support program.

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Compassion-Focused Therapy (Cft) As An Intervention Against Suicidal Ideation In Newly Diagnosed People Living With Hiv/Aids (Plwha) Attending A Nigerian Maternity Teaching Hospital

Global Psychiatry ◽

10.2478/gp-2020-0012 ◽

2020 ◽

Vol 3 (1) ◽

pp. 104-112

Author(s):

A. Ifeanyichukwu Ogueji ◽

M. Maia Okoloba

Keyword(s):

Antiretroviral Therapy ◽

Suicidal Ideation ◽

Teaching Hospital ◽

Intervention Group ◽

Hiv Care ◽

People Living With Hiv ◽

Newly Diagnosed ◽

Compassion Focused Therapy ◽

Living With Hiv ◽

Hiv Aids

AbstractObjectivesIn Sub-Saharan Africa, Nigeria is currently home to many people living with HIV/AIDS (PLWHA), and suicidal ideation is amongst the common early problems of newly diagnosed PLWHA. This reflects the importance of including psychotherapy in HIV care. In this regard, compassion-focused therapy (CFT) is the one that has not been a point of study for reducing suicidal risks in newly diagnosed PLWHA despite the relevance of CFT to the treatment/management of persons living with self-criticism or self-harm. To bridge this gap, we examined the use of CFT as an intervention against suicidal ideation in newly diagnosed PLWHA receiving antiretroviral therapy at the Adeoyo Maternity Teaching Hospital in Ibadan, Oyo state, Nigeria.MethodsTwenty-two participants (mean age = 40 ± 5.6 years) with less than 1-month-old clinical diagnosis of HIV who have recently thought about suicide because of the new HIV-positive diagnosis were purposively sampled and randomly assigned into the intervention and control groups. The CFT module and scale for suicide ideation were the research instruments. All data collected were analysed using SPSS (v.22.0), and statistical significance was determined at P<0.05.ResultsThe findings established that after administering CFT to the intervention group, the mean score for suicidal ideation was significantly lower in the intervention group compared with that in the control group.ConclusionThe results suggest that CFT has the potential to reduce suicidal ideation in newly diagnosed PLWHA; therefore, in addition to the antiretroviral therapy, the administration of CFT should be included in the early stage of HIV care, to reduce the risk of suicide that is associated with newly living with HIV/AIDS.

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Reducing Undernutrition through Counseling on Diversified Food Intake among Adult People Living with HIV on HAART, Northern Ethiopia

Journal of Nutrition and Metabolism ◽

10.1155/2020/9858619 ◽

2020 ◽

Vol 2020 ◽

pp. 1-10

Author(s):

Weldegebrial Hayelom Tedla ◽

Alemseged Aregay ◽

Kidanu Gebremariam ◽

Mulugeta Woldu Abrha ◽

Haftom Gebrehiwot Weldearegay

Keyword(s):

Antiretroviral Therapy ◽

Statistical Significance ◽

People Living With Hiv ◽

Northern Ethiopia ◽

Monthly Income ◽

Nutritional Counseling ◽

Diet Diversity ◽

Catabolic State ◽

Living With Hiv ◽

Hiv Aids

Background. HIV/AIDS and malnutrition are interrelated and exacerbate one another in a vicious cycle. As HIV infection progresses it causes catabolic state and increases susceptibility to other infections, leading to progressive aggravation of undernutrition. However, data are lacking in Ethiopia on determinants of undernutrition among people living with HIV on antiretroviral therapy. Therefore, this study aimed to assess determinants of undernutrition among adult HIV/AIDS patients in Northern Ethiopia. Method. Facility-based unmatched case-control study was conducted among 324 randomly selected people living with HIV on antiretroviral therapy (ART). A structured and pretested interviewer questionnaire was used to collect data, while digital Seca weight and Seca measuring rod were used to measure weight and height, respectively. Logistic regression was used to identify independent factors of undernutrition, and p value <0.05 was declared for statistical significance. All statistical analyses were performed using SPSS 21™. Result. This study revealed that people of younger age and those on ART (AOR = 0.29 (95% CI: 0.10, 0.84)) had low risk of being undernourished. However, average individual monthly income (AOR = 2.61 (95% CI: 1.48, 4.61)), not receiving nutritional counseling during visits (AOR = 2.5 (95% CI: 1.52–3.89)), and low diet diversity (AOR = 10.55 (95% CI: 4.17, 26.73)) had higher odds of undernutrition among people living with HIV/AIDS. Conclusion. Age of patients, average monthly income, nutritional counseling during visits, and diet diversity were the independent factors of undernutrition. Counseling on well-timed and sufficient consumption of nutritious foods, economic strengthening, and livelihood activities is important. Future longitudinal study is necessary to elucidate the problem of undernutrition among people living with HIV/AIDS.

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