scholarly journals Predictors of mortality among adult people living with HIV/AIDS on antiretroviral therapy at Suhul Hospital, Tigrai, Northern Ethiopia: a retrospective follow-up study

2019 ◽  
Vol 38 (1) ◽  
Author(s):  
Kebede Haile Misgina ◽  
Meresa Gebremedhin Weldu ◽  
Tewodros Haile Gebremariam ◽  
Negassie Berhe Weledehaweria ◽  
Haileslasie Berhane Alema ◽  
...  

Abstract Background Ethiopia is striving to achieve a goal of “zero human immune deficiency virus/acquired immune deficiency syndrome (HIV/AIDS)-related deaths.” However, little has been documented on the factors that hamper the progress towards achieving this goal. Therefore, the ultimate aim of this study was to determine predictors of mortality among adult people living with HIV/AIDS on antiretroviral therapy (ART). Methods A retrospective follow-up study was employed on all adult HIV/AIDS patients who started ART between January 1 and December 30, 2010, at Suhul Hospital, Tigrai Region, Northern Ethiopia. Data were collected by trained fourth-year Public Health students using a checklist. Finally, the collected data were entered into SPSS version 16. Then after, Kaplan-Meier curves were used to estimate survival probability, the log-rank test was used for comparing the survival status, and Cox proportional hazards model were applied to determine predictors of mortality. Results The median follow-up period was 51 months (ranging between 1 and 60 months, inter-quartile range (IQR) = 14 months). At the end of follow-up, 37 (12.5%) patients were dead. The majority of these cumulative deaths, 19 (51.4%) and 29 (78.4%), occurred within 3 and 4 years of ART initiation respectively. Consuming alcohol (adjusted hazard ratio (AHR) = 2.23, 95% CI = 1.15, 4.32), low body weight (AHR = 2.38, 95% CI = 1.03, 5.54), presence of opportunistic infections (AHR = 2.18, 95% CI = 1.09, 4.37), advanced WHO clinical stage (AHR = 2.75, 95% CI = 1.36, 5.58), and not receiving isoniazid prophylactic therapy (AHR = 3.00, 95% CI = 1.33, 6.74) were found to be independent predictors of mortality. Conclusion The overall mortality was very high. Baseline alcohol consumption, low body weight, advanced WHO clinical stage, the presence of opportunistic infections, and not receiving isoniazid prophylactic therapy were predictors of mortality. Strengthening behavioral and nutritional counseling with close clinical follow-up shall be given much more emphasis in the ART care and support program.

2010 ◽  
Vol 67 (10) ◽  
pp. 856-860
Author(s):  
Katarina Jankovic-Terzic ◽  
Vera Begic ◽  
Bojana Dacic-Krnjaja

Introduction. Serbia has 2.287 registered HIV positive persons. A certain number has ocular complications which are mainly the result of opportunistic infections accompanying this illness. Due to a highly stigmatizing environment for people living with HIV/AIDS in Serbia, they do not always seek doctors assistance despite the fear of losing their sight. Case report. We presented ophthalmologic status of nine HIV positive persons, all at the different phases of the illness. The decrease in the visual acuity was the first symptom which led to the diagnosis of HIV infection in two of our patients. Conclusion. Ophthalmologist has an important role in the multidisciplinary approach to patients with HIV/AIDS from introducing the diagnosis to the follow-up and the treatment of ocular complications which may accompany this chronic illness. With the active involvement of eye professionals serious consequences can be prevented, which have not only medical but also social and economic implications on the individual and the society as a whole.


2019 ◽  
Vol 3 (3) ◽  
pp. 175
Author(s):  
Sukarsi Rusti

<p><em>H</em><em>I</em><em>V/AIDS disease is a health problem in indonesia. The problem cause of</em><em> </em><em>the number of morbility and mortality that still hight. It is cause of long term</em><em> </em><em>infection, adherance consuming the drungs and opportunistic that can deastroy the</em><em> </em><em>imun system </em><em>of People Living With HIV/AIDS (PLHIV)</em><em>.  The purpose of this research is to identify the factors</em><em> </em><em>related to the people living with </em><em>PLHIV</em><em> </em><em>in Achmad Muchtar Hospital Bukittinggi</em></p><p><em>2016.</em><em></em></p><p><em>This research was conducted by a retrospective cohort design approach, doing  research  of the death of people who living with HIV by observing the patient’s  medical  record  from  2014-2015.  The  research  of  study  were  215 patient’s  who  is  criteria  inclusion.  Analysis  data  using  test  chi-square.  who became the independent  variable is  long  infection,  adherance  comsuming the </em><em>Anti Retroviral (ARV)</em><em> </em><em>, and opportunistic infection and dependent variable that survive the HIV people life.</em><em></em></p><p><em>The research showed that among  215 patients with the number of deaths 39 people ( 18,% ), stages 3 and 4 (&gt;5 th) is 89 people ( 41.4% ), not adherence is  77 people ( 35.8% ), and who suffered an opportunistic infection were 61 people (28.4% ). The statistical test relationships survival of people  living with</em><em> </em><em>H</em><em>I</em><em>V with long-term  infection obtained p value </em><em>=</em><em> </em><em>0,000</em><em> and </em><em>RR = 0,019 ( confidence interfal 95 % with alpha = 0.05 )</em><em>, </em><em>a</em><em>dherance comsuming the </em><em>ARV </em><em>obtained p value  </em><em>= </em><em>0,000 </em><em>and</em><em>  </em><em>RR = 0,494 ( confidence interfal  95 % with alpha = 0.05 ), infection opportunistic</em><em> obtained</em><em> </em><em>p value </em><em>= </em><em>0,000 </em><em>and</em><em> </em><em>RR = 0,361 ( confidence interfal 95 % with αlpha = 0.05 ).</em></p><p><em>From these findings, it can be concluded that  the  long-term  infection,  adherence  ARV  and opportunistic infections associated with survival of people living with HIV. Of the three variables obtained interrelated and value the highest association is long-term  infection</em><em>.</em></p>


2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Ketema Bizuwork Gebremedhin ◽  
Tadesse Bedada Haye

Background. Globally, anemia, among people living with HIV/AIDS, is a major public health problem. It has a significant effect on the progression of HIV/AIDS to advanced stages and there are a number of factors that often affect anemia. However, there is little insight regarding factors affecting anemia among HIV/AIDS patients in developing countries, including Ethiopia. Objective. This study aimed at investigating factors affecting anemia among people living with HIV/AIDS taking ART drug at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Methods. A hospital based cross-sectional study design was used to assess factors affecting anemia among people living with HIV/AIDS. Structured checklist was used to gather information from charts of patients selected by simple random sampling method. We analyzed the data to identify factors associated with anemia among people with HIV/AIDS using logistic regression models. Results. A total of 301 selected charts were reviewed. The median age was 38 ± 10.38. The majority (62.5%) of the patients were taking ZDV-containing ART drug (ZDV/3TC/NVP). The overall anemia prevalence was 34.6%, while about 5%, 15.6%, and 14% of the patients had severe, moderate, and mild prevalence of anemia, respectively. Factors that were found to affect anemia among these patients include gender (OR = 2.26 [95% CI: 1.22, 4.16]), occupation (OR: 0.57 [95%CI: 0.35, 0.92]), WBC count (OR = 2.30 [95% CI: 1.29, 4.09]), platelet count (OR = 2.89 [95% CI: 0.99, 8.41]), nutritional status (OR = 2.05 [95% CI: 0.69, 6.02]), and WHO clinical stage of HIV/AIDS (OR = 3.69 [95% CI: 1.86, 7.31]). Conclusions. About one in three patients was found to be anemic. Intervention aimed at diagnosing and treating anemia among people living with HIV/AIDS should be considered.


2019 ◽  
Vol 72 (5) ◽  
pp. 1161-1166
Author(s):  
Ivana Cristina Vieira de Lima ◽  
Marli Teresinha Gimeniz Galvão ◽  
Samyla Citó Pedrosa ◽  
Odaleia Oliveira Farias ◽  
Camila Aparecida Costa Silva ◽  
...  

ABSTRACT Objective: To assess a specific instant messaging application as a tool of care for people living with HIV/aids, based on analysis of the interactions between nurse and patients. Method: Descriptive, quantitative study with 102 patients from two outpatient infectious disease clinics of Fortaleza, Ceará. During four months, participants received a message every 15 days, totaling eight messages, regarding: adherence to antiretroviral therapy; physical activity; social support; self-esteem; anxiety/depression; eating habits; alcohol and drugs; and sexuality. Results: There were 816 interactions, especially for dialogs about performing physical activity (27.87%), sharing of signs and symptoms (18.03%), report of engagement with treatment (9.84%) and requests of information on the intake of medicine (9.84%). Most participants showed satisfaction with the follow-up, with willingness to continue receiving messages (90.58%). Conclusion: The use of this application is a viable strategy to improve care for people with HIV by promoting instant communication.


2019 ◽  
Author(s):  
Adugna Oluma ◽  
Muktar Abadiga ◽  
Getu Mosisa ◽  
Werku Etafa ◽  
Ginenus Fekadu

Abstract Background : Food insecurity and HIV/AIDS are intertwined in a vicious cycle through nutritional, mental health, and behavioral pathways. Food insecurity is a potentially important barrier to the success of antiretroviral treatment, increased hospitalizations, and higher morbidity among HIV-infected individuals in resource-poor settings particularly in sub-Saharan Africa including Ethiopia. Therefore, the purpose of this study was to assess the prevalence of food insecurity and its associated factors among adult people living with HIV/AIDS on follow up receiving ART at public hospitals of wollega zone, west Ethiopia. Methods : An institutional-based cross-sectional study design was conducted on a sample of 428 among people living with HIV/AIDS on follow up receiving anti-retroviral therapy at public hospitals of wollega zones. Data was collected using the Household Food Insecurity Access Scale and dietary diversity scale by interviewer-administered questionnaires. The data was checked, cleaned and entered into Epi data version 3.1 and then exported into Statistical Package for the Social Sciences (SPSS) window version 21 for analysis. Descriptive statistics - cross-tabulation frequency table, mean, standard deviation, percentage, were employed. Bivariate and multiple logistic regression analyses were used with AOR at CI 95% and p<0.05 were used. Result: The overall prevalence of food insecurity among PLWHA receiving ART therapy was 68.8% which was partitioned as mild (23.32%), moderate (29.09%) and severe (16.35%) food in secured. Being single [AOR=3.507(1.377, 8.934)], illiterate [AOR=5.234(1.747, 15.686)], cigarette smoking [AOR=3.577(2.104, 6.081)], presence of anemia (AOR=2.650(1.563, 4.493)] and inadequate dietary diversity [AOR=2.870(1.088, 7.569)] were predictors of food insecurity. Conclusion : The prevalence of food insecurity was relatively high. Educational status, marital status, cigarette smoking, presence of anemia, opportunistic infection and inadequate dietary diversity were the major significant factors affecting food insecurity. We recommended Wollega Zonal Health Bureaus to effectively intervene in behavioral modification and health information dissemination (HID) which is the key strategies to improve food security.


2017 ◽  
Author(s):  
indrayanti

Individual infected with HIV/AIDS, called by people living with HIV/AIDS, had various problems such as helplessness, discriminated, status of aggrieved, dispossession and the risk of opportunistic infections. PLWH needs strength to cope with all health problems. They need high self efficacy that was proponent the success of PLWH care. Nursing interventions that have an impact in improving the self efficacy PLWH was required. This study aimed to know the influences of hypnocaring toward PLWH self efficacy at Yogyakarta, Indonesia. The study design was quasi experiment with pre post control group. The data collection was done by consecutive sampling and it was identified 60 respondents. Hypnocaring therapy was chosen as intervention. It equipped with health education and hypnotic sessions that was provided for three sessions in one week. The PLWH self efficacy measured before intervention and 2 weeks after the intervention process finished. The result shows that hypnocaring had an influenced to PLWH self efficacy (p &lt; 0.01). Self efficacy mean increased from 65.37 into 72.93. Hypnocaring was suggested to be given within support peer groups. Hypnocaring also appealed to be one of community nurse competence in the provision of complementary therapy to PLWH.


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