scholarly journals Umbilical cord stem cells released from alginate–fibrin microbeads inside macroporous and biofunctionalized calcium phosphate cement for bone regeneration

2012 ◽  
Vol 8 (6) ◽  
pp. 2297-2306 ◽  
Author(s):  
Wenchuan Chen ◽  
Hongzhi Zhou ◽  
Michael D. Weir ◽  
Chongyun Bao ◽  
Hockin H.K. Xu
2012 ◽  
Vol 18 (7-8) ◽  
pp. 816-827 ◽  
Author(s):  
Wenchuan Chen ◽  
Hongzhi Zhou ◽  
Minghui Tang ◽  
Michael D. Weir ◽  
Chongyun Bao ◽  
...  

2014 ◽  
Vol 93 (7) ◽  
pp. 618-625 ◽  
Author(s):  
P. Wang ◽  
L. Zhao ◽  
W. Chen ◽  
X. Liu ◽  
M.D. Weir ◽  
...  

2015 ◽  
Vol 37 (1se) ◽  
Author(s):  
Nguyen Van Hanh ◽  
Vi Dai Lam ◽  
Nguyen Huu Duc ◽  
Do Trung Kien ◽  
Nguyen Viet Linh

2020 ◽  
Vol 15 (3) ◽  
pp. 219-232
Author(s):  
Ifrah Anwar ◽  
Usman A. Ashfaq ◽  
Zeeshan Shokat

The liver is a vital organ for life and the only internal organ that is capable of natural regeneration. Although the liver has high regeneration capacity, excessive hepatocyte death can lead to liver failure. Various factors can lead to liver damage including drug abuse, some natural products, alcohol, hepatitis, and autoimmunity. Some models for studying liver injury are APAP-based model, Fas ligand (FasL), D-galactosamine/endotoxin (Gal/ET), Concanavalin A, and carbon tetrachloride-based models. The regeneration of the liver can be carried out using umbilical cord blood stem cells which have various advantages over other stem cell types used in liver transplantation. UCB-derived stem cells lack tumorigenicity, have karyotype stability and high immunomodulatory, low risk of graft versus host disease (GVHD), low risk of transmitting somatic mutations or viral infections, and low immunogenicity. They are readily available and their collection is safe and painless. This review focuses on recent development and modern trends in the use of umbilical cord stem cells for the regeneration of liver fibrosis.


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