Investigation of adhesive interactions in the specific targeting of Triptorelin-conjugated PEG-coated magnetite nanoparticles to breast cancer cells

2018 ◽  
Vol 71 ◽  
pp. 363-378 ◽  
Author(s):  
Jingjie Hu ◽  
Sina Youssefian ◽  
John Obayemi ◽  
Karen Malatesta ◽  
Nima Rahbar ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Magnetite Nanoparticles ◽  
Breast Cancer Cells ◽  
Specific Targeting ◽  
Adhesive Interactions

Adhesion of ligand-conjugated biosynthesized magnetite nanoparticles to triple negative breast cancer cells

2017 ◽  
Vol 68 ◽  
pp. 276-286 ◽  
Author(s):  
John D. Obayemi ◽  
Jingjie Hu ◽  
Vanessa O. Uzonwanne ◽  
Olushola S. Odusanya ◽  
Karen Malatesta ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Triple Negative Breast Cancer ◽  
Magnetite Nanoparticles ◽  
Breast Cancer Cells ◽  
Triple Negative

Adhesion Between Anti-EphA2 Antibody-Coated AFM Tips and Breast Cancer Cells

2009 ◽  
Vol 1237 ◽  
Author(s):  
Emily Paetzell ◽  
Andrew Bogorad ◽  
Juan Meng ◽  
Winston oluwole Soboyejo
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Adhesion Force ◽  
Normal Breast ◽  
Atomic Force ◽  
Afm Tips ◽  
Ligand Interactions ◽  
Breast Cells ◽  
Adhesive Interactions

AbstractThis paper presents the results of atomic force microscope (AFM) measurements of the adhesion force between MDA-MB-231 breast cancer cells and anti-EphA2 antibody-coated AFM tips. As a control, the adhesive interactions are measured between Hs578Bst normal breast cells and anti-EphA2 antibody-coated AFM tips. The measurements show conclusively that the adhesive forces to breast cancer cells are over five times greater than those to normal breast cells. The increase is attributed largely to the interactions between anti-EphA2 antibody and over-expressed EphA2 receptors that are revealed by the staining of receptor-ligand interactions. The implications of the results are discussed for the localized targeting and treatment of cancer with antibody-conjugated nanoparticles.

Tumor-targeted folate-decorated albumin-stabilised silver nanoparticles induce apoptosis at low concentration in human breast cancer cells

RSC Advances ◽  
2015 ◽  
Vol 5 (105) ◽  
pp. 86242-86253 ◽  
Author(s):  
Bharat Bhushan ◽  
P. Gopinath
Keyword(s):  
Breast Cancer ◽  
Silver Nanoparticles ◽  
Bovine Serum Albumin ◽  
Cancer Cells ◽  
Human Breast Cancer ◽  
Breast Cancer Cells ◽  
Human Breast Cancer Cells ◽  
Human Breast ◽  
Ag Nps ◽  
Specific Targeting

The current study exploits the folate-mediated delivery of bovine serum albumin (BSA) stabilized Ag NPs and thereby overcomes various drawbacks associated with non-specific targeting.

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