Regulatory systems for hypoxia-inducible gene expression in ischemic heart disease gene therapy

2011 ◽  
Vol 63 (8) ◽  
pp. 678-687 ◽  
Author(s):  
Hyun Ah Kim ◽  
Taiyoun Rhim ◽  
Minhyung Lee
Keyword(s):  
Gene Expression ◽  
Gene Therapy ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Disease Gene ◽  
Ischemic Heart ◽  
Inducible Gene Expression ◽  
Regulatory Systems ◽  
Inducible Gene

Nursing diagnosis intolerance to the activity and inefficient cardiopulmonary perfusion tissue: evaluation in patients undergoing gene therapy - preview note

2009 ◽  
Vol 3 (4) ◽  
pp. 1242
Author(s):  
Clarissa Garcia Rodrigues ◽  
Maria Antonieta Moraes ◽  
Emiliane Nogueira de Souza ◽  
Jaquelini Messer Sauer ◽  
Andréia Orjana Ribeiro Coutinho ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Myocardial Revascularization ◽  
Ischemic Heart ◽  
Friedman Test ◽  
Nursing Assessment ◽  
Nursing Diagnosis ◽  
Before And After ◽  
Dichotomous Variables

Objective: to evaluate and compare the frequency of nursing diagnosis activity intolerance and ineffective tissue cardiopulmonary perfusion in advanced ischemic heart disease patients before and after gene therapy for myocardial revascularization. Methods: cohort study, in which 20 patients developed ischemic heart disease treated with gene therapy are undergoing clinical evaluation of two nurses with experience of minimum three years in cardiology, to identify the presence or absence of the nursing diagnosis activity intolerance and ineffective tissue cardiopulmonary perfusion. These evaluations will be done before gene therapy and three and six months afterwards. The data will be tabulated for later analysis of absolute and relative frequency as well as comparison between the three moments. Will be used for the coefficient of Kappa analysis of agreement between the assessments of nursing. To compare the dichotomous variables will be used for the Cochran Q-test and for ordinal variables will be used the Friedman test. Descriptors: nursing assessment; nursing diagnosis; myocardial ischemia. 

Gene therapy for ischemic heart disease

1996 ◽  
Vol 11 (4) ◽  
pp. 361-368 ◽  
Author(s):  
Steven Malosky ◽  
Daniel M. Kolansky
Keyword(s):  
Gene Therapy ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Ischemic Heart

scholarly journals Аdipose tissue expression of ABCA1 and ABCG1 transporters genes in obesity, metabolic syndrome and ischemic heart disease

2020 ◽  
pp. 56-57
Author(s):  
В.В. Мирошникова ◽  
А.А. Пантелеева ◽  
И.А. Побожева ◽  
Н.Д. Разгильдина ◽  
К.В. Драчева ◽  
...  
Keyword(s):  
Gene Expression ◽  
Metabolic Syndrome ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Cardiometabolic Risk ◽  
Tissue Expression ◽  
Ischemic Heart ◽  
Cholesterol Transporters

Ожирение ассоциировано с повышенным риском развития метаболических нарушений и сердечно-сосудистых заболеваний. В нашем исследовании мы показали, что экспрессия генов транспортеров холестерина ABCA1 и ABCG1 в жировой ткани может играть роль в развитии ожирения, дислипидемии, метаболического синдрома и ишемической болезни сердца (ИБС). Obesity is linked to increased cardiometabolic risk. Our study shows that cholesterol transporters ABCA1 and ABCG1 gene expression plays a role in development of obesity, dyslipidemia, metabolic syndrome and ischemic heart disease.

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