Long-term results of surgical excision of conjunctival retention cyst using trypan blue with methylcellulose

ABCs are expansile osteolytic lesions typically containing blood-filled spaces separated by fibrous septae. Standard treatment includes surgical resection or curettage and packing; however, for some spinal lesions, the standard approach is not optimal. One therapeutic strategy is to treat spinal ABC with an agent that targets a pathway that is dysregulated in a disease with similar pathophysiology. Denosumab, a human monoclonal antibody to RANKL is effective in the treatment of GCT's. Spinal ABCs are a therapeutic challenge and local recurrence is a concern. We report a case of aggressive recurrent ABC of dorsal spine in a 14-year old female with progressive neurologic deficit who underwent surgical excision and decompression with a recurrence in a short period for which a decompression and fixation was done. She had a recurrence after an asymptomatic period of 6 months and neurologic worsening. Having ruled out use of embolization and radiotherapy, a remission was achieved by treatment with Denosumab using the regimen for GCTs for a duration of 6 months. Follow-up MRI and CT scans at 24 months following inception of Denosumab depicted complete resolution and no recurrence. We conclude that Denosumab can result in symptomatic and radiological improvement in the recurrent locally aggressive ABC and may be useful in selected cases. Long-term results are mandatory to confirm the efficacy of Denosumab and to evaluate local recurrence after stopping Denosumab.

Download Full-text

Bowen’s Disease: Long-term Results of Treatment with 5-Fluorouracil Cream, Photodynamic Therapy or Surgical Excision

Acta Dermato Venereologica ◽

10.2340/00015555-2777 ◽

2018 ◽

Vol 98 (1) ◽

pp. 114-115 ◽

Cited By ~ 5

Author(s):

M Jansen ◽

D Appelen ◽

P Nelemans ◽

V Winnepenninckx ◽

N Kelleners-Smeets ◽

...

Keyword(s):

Photodynamic Therapy ◽

Surgical Excision ◽

Long Term Results ◽

Bowen’S Disease ◽

Bowen's Disease ◽

Results Of Treatment

Download Full-text

Long-Term Results of Wide Surgical Excision in 106 Patients with Hidradenitis Suppurativa

Dermatologic Surgery ◽

10.1046/j.1524-4725.2000.00043.x ◽

2000 ◽

Vol 26 (7) ◽

pp. 638-643 ◽

Cited By ~ 159

Author(s):

Rainer Rompel ◽

Johannes Petres

Keyword(s):

Hidradenitis Suppurativa ◽

Surgical Excision ◽

Long Term Results ◽

Wide Surgical Excision

Download Full-text

LAPAROSCOPIC TREATMENT OF CONGENITAL NONPARASITIC LIVER CYSTS IN NEWBORNS

PEDIATRIA Journal named after G N SPERANSKY ◽

10.24110/0031-403x-2021-100-1-253-258 ◽

2021 ◽

Vol 100 (1) ◽

pp. 253-258

Author(s):

Yu.A. Kozlov ◽

◽

V.A. Novozhilov ◽

I.N. Weber ◽

A.A. Rasputin ◽

...

Keyword(s):

Demographic Data ◽

Surgical Excision ◽

Early Postoperative Period ◽

Long Term Results ◽

Histological Structure ◽

Laparoscopic Treatment ◽

Liver Cysts ◽

Hepatic Cysts ◽

Laparoscopic Excision

Congenital nonparasitic liver cysts in newborns are rare. Surgical excision of these formations is necessary to prevent complications. Reports of laparoscopic treatment of simple liver cysts in children are also rare. Authors present a series of endosurgical treatment of patients, numbering 3 children and coming from a single surgical center, and compare it with the literature data known to date. Data of 3 patients with nonparasitic liver cysts were collected at the Center for Neonatal Surgery, beginning in 2014. The analysis of the patient's demographic data and parameters of hepatic cysts (location, histological structure) is performed. Early and long-term results of laparoscopic operations were studied. All patients were newborns: 2 girls and 1 boy. The primary diagnosis was set during prenatal ultrasound examination. In all patients a complete resection of pathological liver formations was performed using laparoscopy. There were no complications during early postoperative period. In the long-term follow-up period, there were no disease recurrences. The study presents one of the largest series of laparoscopic excision of nonparasitic liver cysts in newborns. The study revealed that laparoscopy is a safe and effective method of treating of congenital hepatic cysts.

Download Full-text

Erratum: Long-term results of trypan blue dye irrigation in the capsular bag to prevent posterior capsule opacification: A randomized trial

Indian Journal of Ophthalmology ◽

10.4103/0301-4738.221858 ◽

2018 ◽

Vol 66 (1) ◽

pp. 181

Keyword(s):

Randomized Trial ◽

Trypan Blue ◽

Posterior Capsule Opacification ◽

Long Term Results ◽

Posterior Capsule ◽

Blue Dye ◽

Capsular Bag

Download Full-text

LONG TERM RESULTS AFTER STAPLED HEMORRHOIDOPEXY ALONE AND COMPLEMENTED BY EXCISIONAL HEMORRHOIDECTOMY: A RETROSPECTIVE COHORT STUDY

ABCD Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) ◽

10.1590/0102-6720201600030008 ◽

2016 ◽

Vol 29 (3) ◽

pp. 159-163 ◽

Cited By ~ 3

Author(s):

Sergio Eduardo Alonso ARAUJO ◽

Lucas de Araujo HORCEL ◽

Victor Edmond SEID ◽

Alexandre Bruno BERTONCINI ◽

Sidney KLAJNER

Keyword(s):

Cohort Study ◽

Surgical Excision ◽

Stapled Hemorrhoidopexy ◽

Long Term Results ◽

External Hemorrhoid ◽

Symptomatic Recurrence ◽

Excisional Surgery ◽

Symptom Recurrence

ABSTRACT Background: Stapled hemorrhoidopexy is associated with less postoperative pain and faster recovery. However, it may be associated with a greater risk of symptomatic recurrence. We hypothesized that undertaking a limited surgical excision of hemorrhoid disease after stapling may be a valid approach for selected patients. Aim: To compare long-term results after stapled hemorrhoidopexy with and without complementation with closed excisional technique. Method: In a retrospective uni-institutional cohort study, sixty-five (29 men) patients underwent stapled hemorrhoidopexy and 21 (13 men) underwent stapled hemorrhoidopexy with excision. The same surgeons operated on all cases. Patients underwent stapled hemorrhoidectomy associated with excisional surgery if symptoms attributable to external hemorrhoid piles were observed preoperatively, or if residual prolapse or bulky external disease was observed after the firing of the stapler. A closed excisional diathermy hemorrhoidectomy without vascular ligation was utilized in all complemented cases. All clinical variables were obtained from a questionnaire evaluation obtained through e-mail, telephone interview, or office follow-up. Results: The median duration of postoperative follow-up was 48.5 (6-40) months. Patients with grades 3 and 4 hemorrhoid disease were operated on more frequently using stapled hemorrhoidopexy complemented with excisional technique (95.2% vs. 55.4%, p=0.001). Regarding respectively stapled hemorrhoidopexy and stapled hemorrhoidopexy complemented with excision, there was no difference between the techniques in relation to symptom recurrence (43% and 33%, p=0.45) and median interval between surgery and symptom recurrence (30 (8-84) and 38.8 (8-65) months, p=0.80). Eight (12.3%) patients were re-operated after stapled hemorrhoidopexy and 2 (9.6%), after hemorrhoidopexy with excision (p=0.78). Patient distribution in both groups according to the degree of postoperative satisfaction was similar (p=0.97). Conclusion: Stapled hemorrhoidopexy combined with an excisional technique was effective for more advanced hemorrhoid disease. The combination may have prevented symptomatic recurrence associated to stapled hemorrhoidopexy alone.

Download Full-text