Maternal cerebral blood flow during normal pregnancy: a cross-sectional study

2010 ◽  
Vol 203 (5) ◽  
pp. 475.e1-475.e6 ◽  
Author(s):  
Ori Nevo ◽  
Jean F. Soustiel ◽  
Israel Thaler
Author(s):  
Mike Seed ◽  
Joshua F P van Amerom ◽  
Shi-Joon Yoo ◽  
Bahiyah Al Nafisi ◽  
Lars Grosse-Wortmann ◽  
...  

Author(s):  
I Made Mahadinata Putra ◽  
I Gede P Surya

Objective: To determine the difference of 8-hydroxy-2-deoxyguanocyne (8-OHdG) serum level in women experiencing blighted ovum and women with normal pregnancy. Method: This was a cross sectional study with 82 samples, divided into two groups. Thirty two cases of blighted ovum and 51 cases of normal pregnancies, with 7-12 weeks gestational age. The examination of 8-OHdG serum level, was performed with the venous blood taken from the cubiti veins, and its 8-OHdG serum quantities were than examined at the Pathology Lab. at Sanglah General Hospital. Data was analyzed with the Shapiro Wilk Test and the t independent test with alpha 0.05. Result: The average 8-OHdG serum level in women with blighted ovum and normal pregnancies were 0.177 (SD 0.06) ng/ml and 0.111 (SD 0.01)ng/ml, and significantly different (p<0.05). The cut off value of 8-OHdG serum level was 0.138 ng/ml with sensitivity of 96.1% and specificity of 80.6%. Conclusion: The level of 8-OHdG serum was higher in women with blighted ovum than in women with normal pregnancies.  Keywords: 8-OHdG serum level, blighted ovum, and normal pregnancy.


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