scholarly journals Transcriptomic Characterization of Human Choroidal Neovascular Membranes Identifies Calprotectin as a Novel Biomarker for Patients with Age-Related Macular Degeneration

2020 ◽  
Vol 190 (8) ◽  
pp. 1632-1642 ◽  
Author(s):  
Anja Schlecht ◽  
Stefaniya Boneva ◽  
Markus Gruber ◽  
Peipei Zhang ◽  
Ralf Horres ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Age Related

scholarly journals Hyperspectral autofluorescence characterization of drusen and sub-RPE deposits in age-related macular degeneration

2021 ◽  
Vol 6 ◽  
pp. 4-4
Author(s):  
Yuehong Tong ◽  
Thomas Ach ◽  
Christine A. Curcio ◽  
R. Theodore Smith
Keyword(s):  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Age Related

scholarly journals Effects of Mitochondrial-Derived Peptides (MDPs) on Mitochondrial and Cellular Health in AMD

Cells ◽  
2020 ◽  
Vol 9 (5) ◽  
pp. 1102 ◽  
Author(s):  
Sonali Nashine ◽  
M. Cristina Kenney
Keyword(s):  
Mitochondrial Dysfunction ◽  
Macular Degeneration ◽  
Therapeutic Targets ◽  
Mechanisms Of Action ◽  
Age Related Macular Degeneration ◽  
Age Related

Substantive evidence demonstrates the contribution of mitochondrial dysfunction in the etiology and pathogenesis of Age-related Macular Degeneration (AMD). Recently, extensive characterization of Mitochondrial-Derived Peptides (MDPs) has revealed their cytoprotective role in several diseases, including AMD. Here we summarize the varied effects of MDPs on cellular and mitochondrial health, which establish the merit of MDPs as therapeutic targets for AMD. We argue that further research to delve into the mechanisms of action and delivery of MDPs may advance the field of AMD therapy.

Characterization of Neovascular Age-Related Macular Degeneration Patients with Outer Retinal Tubulations

2013 ◽  
Vol 229 (3) ◽  
pp. 147-151 ◽  
Author(s):  
F. Faria-Correia ◽  
R. Barros-Pereira ◽  
L. Queirós-Mendanha ◽  
S. Fonseca ◽  
L. Mendonça ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Age Related

Characterization of a yucatan minipig laser-induced choroidal neovascularization model of neovascular age-related macular degeneration

2017 ◽  
Vol 280 ◽  
pp. S156
Author(s):  
Joshua Bartoe ◽  
Ryan Boyd ◽  
Krishna Yekkala ◽  
Betsy Geddings ◽  
Matthew Leahy ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Choroidal Neovascularization ◽  
Age Related Macular Degeneration ◽  
Age Related
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