Hyperspectral autofluorescence characterization of drusen and sub-RPE deposits in age-related macular degeneration

Annals of Eye Science ◽

10.21037/aes-20-12 ◽

2021 ◽

Vol 6 ◽

pp. 4-4

Author(s):

Yuehong Tong ◽

Thomas Ach ◽

Christine A. Curcio ◽

R. Theodore Smith

Keyword(s):

Macular Degeneration ◽

Age Related Macular Degeneration ◽

Download Full-text

Characterization of Drusen and Hyperreflective Foci as Biomarkers for Disease Progression in Age-Related Macular Degeneration Using Artificial Intelligence in Optical Coherence Tomography

JAMA Ophthalmology ◽

10.1001/jamaophthalmol.2020.1376 ◽

2020 ◽

Vol 138 (7) ◽

pp. 740 ◽

Author(s):

Sebastian M. Waldstein ◽

Wolf-Dieter Vogl ◽

Hrvoje Bogunovic ◽

Amir Sadeghipour ◽

Sophie Riedl ◽

...

Keyword(s):

Artificial Intelligence ◽

Optical Coherence Tomography ◽

Macular Degeneration ◽

Disease Progression ◽

Age Related Macular Degeneration ◽

Optical Coherence ◽

Hyperreflective Foci ◽

Download Full-text

Phenotypic Characterization of Complement Factor H R1210C Rare Genetic Variant in Age-Related Macular Degeneration

JAMA Ophthalmology ◽

10.1001/jamaophthalmol.2015.0814 ◽

2015 ◽

Vol 133 (7) ◽

pp. 785 ◽

Author(s):

Daniela Ferrara ◽

Johanna M. Seddon

Keyword(s):

Macular Degeneration ◽

Genetic Variant ◽

Factor H ◽

Age Related Macular Degeneration ◽

Complement Factor H ◽

Phenotypic Characterization ◽

Complement Factor ◽

Rare Genetic Variant ◽

Download Full-text

Re: Nguyen et al.: Characterization of poor visual outcomes of neovascular age-related macular degeneration treated with anti-vascular endothelial growth factor agents (Ophthalmology. 2019;126:735-742)

Ophthalmology ◽

10.1016/j.ophtha.2019.10.030 ◽

2020 ◽

Vol 127 (4) ◽

pp. e21

Author(s):

Jae Hui Kim

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Macular Degeneration ◽

Age Related Macular Degeneration ◽

Vascular Endothelial ◽

Visual Outcomes ◽

Age Related ◽

Endothelial Growth Factor

Download Full-text

Transcriptomic Characterization of Human Choroidal Neovascular Membranes Identifies Calprotectin as a Novel Biomarker for Patients with Age-Related Macular Degeneration

American Journal Of Pathology ◽

10.1016/j.ajpath.2020.04.004 ◽

2020 ◽

Vol 190 (8) ◽

pp. 1632-1642 ◽

Author(s):

Anja Schlecht ◽

Stefaniya Boneva ◽

Markus Gruber ◽

Peipei Zhang ◽

Ralf Horres ◽

...

Keyword(s):

Macular Degeneration ◽

Age Related Macular Degeneration ◽

Download Full-text

Synthesis and structural characterization of carboxyethylpyrrole-modified proteins: mediators of age-related macular degeneration

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2009.09.009 ◽

2009 ◽

Vol 17 (21) ◽

pp. 7548-7561 ◽

Author(s):

Liang Lu ◽

Xiaorong Gu ◽

Li Hong ◽

James Laird ◽

Keeve Jaffe ◽

...

Keyword(s):

Macular Degeneration ◽

Structural Characterization ◽

Age Related Macular Degeneration ◽

Age Related ◽

Modified Proteins

Download Full-text

Effects of Mitochondrial-Derived Peptides (MDPs) on Mitochondrial and Cellular Health in AMD

Cells ◽

10.3390/cells9051102 ◽

2020 ◽

Vol 9 (5) ◽

pp. 1102 ◽

Author(s):

Sonali Nashine ◽

M. Cristina Kenney

Keyword(s):

Mitochondrial Dysfunction ◽

Macular Degeneration ◽

Therapeutic Targets ◽

Mechanisms Of Action ◽

Age Related Macular Degeneration ◽

Substantive evidence demonstrates the contribution of mitochondrial dysfunction in the etiology and pathogenesis of Age-related Macular Degeneration (AMD). Recently, extensive characterization of Mitochondrial-Derived Peptides (MDPs) has revealed their cytoprotective role in several diseases, including AMD. Here we summarize the varied effects of MDPs on cellular and mitochondrial health, which establish the merit of MDPs as therapeutic targets for AMD. We argue that further research to delve into the mechanisms of action and delivery of MDPs may advance the field of AMD therapy.

Download Full-text

Characterization of Neovascular Age-Related Macular Degeneration Patients with Outer Retinal Tubulations

Ophthalmologica ◽

10.1159/000346854 ◽

2013 ◽

Vol 229 (3) ◽

pp. 147-151 ◽

Author(s):

F. Faria-Correia ◽

R. Barros-Pereira ◽

L. Queirós-Mendanha ◽

S. Fonseca ◽

L. Mendonça ◽

...

Keyword(s):

Macular Degeneration ◽

Age Related Macular Degeneration ◽

Download Full-text

DETAILED CHARACTERIZATION OF CHOROIDAL MORPHOLOGIC AND VASCULAR FEATURES IN AGE-RELATED MACULAR DEGENERATION AND POLYPOIDAL CHOROIDAL VASCULOPATHY

Retina ◽

10.1097/iae.0000000000001481 ◽

2017 ◽

Vol 37 (12) ◽

pp. 2269-2280 ◽

Author(s):

Preeti Gupta ◽

Daniel Shu Wei Ting ◽

Sri GOWTHAM Thakku ◽

Tien-Yin Wong ◽

Ching-Yu Cheng ◽

...

Keyword(s):

Macular Degeneration ◽

Polypoidal Choroidal Vasculopathy ◽

Age Related Macular Degeneration ◽

Detailed Characterization ◽

Age Related ◽

Choroidal Vasculopathy

Download Full-text

Characterization of a yucatan minipig laser-induced choroidal neovascularization model of neovascular age-related macular degeneration

Toxicology Letters ◽

10.1016/j.toxlet.2017.07.438 ◽

2017 ◽

Vol 280 ◽

pp. S156

Author(s):

Joshua Bartoe ◽

Ryan Boyd ◽

Krishna Yekkala ◽

Betsy Geddings ◽

Matthew Leahy ◽

...

Keyword(s):

Macular Degeneration ◽

Choroidal Neovascularization ◽

Age Related Macular Degeneration ◽

Download Full-text

Characterization of Rod Function Phenotypes Across a Range of Age-Related Macular Degeneration Severities and Subretinal Drusenoid Deposits

Investigative Opthalmology & Visual Science ◽

10.1167/iovs.17-22874 ◽

2018 ◽

Vol 59 (6) ◽

pp. 2411 ◽

Author(s):

Oliver J. Flynn ◽

Catherine A. Cukras ◽

Brett G. Jeffrey

Keyword(s):

Macular Degeneration ◽

Age Related Macular Degeneration ◽

Age Related ◽

Rod Function ◽

Subretinal Drusenoid Deposits

Download Full-text