The Evolution of the Treatment of Acute Myocardial Infarction: A Eulogy to the Coronary Care Unit

2018 ◽  
Vol 122 (4) ◽  
pp. 696-698 ◽  
Author(s):  
Milford G. Wyman ◽  
R. Michael Wyman
1984 ◽  
Vol 23 (04) ◽  
pp. 209-213
Author(s):  
B. J. Northover

SummaryAnalysis of electrocardiograms tape-recorded from patients admitted to hospital with acute myocardial infarction revealed that the pattern of ventricular extrasystolic activity was not significantly different among those who subsequently developed ventricular fibrillation and those who did not. Episodes of ventricular fibrillation occurred predominantly within 4 hours from the start of infarction. Patients were 3 times less likely to survive an episode of ventricular fibrillation if they also had left ventricular failure than if this feature was absent. Management of episodes of ventricular fibrillation was compared in patients before and after the creation of a specially staffed and equipped coronary care unit. The success of electric shock as a treatment for ventricular fibrillation was similar before and after the creation of the coronary care unit. An attempt was made to determine which features in the management of ventricular fibrillation in this and in previously published series were associated with patient survival.


Author(s):  
W S Kilpatrick ◽  
D Wosornu ◽  
J B McGuinness ◽  
A C A Glen

We have measured changes in plasma concentration of creatine kinase MB (CK-MB) and myoglobin in 50 patients admitted to the Coronary Care Unit with chest pain of presumed cardiac origin. Eight serial blood samples were obtained in the 6 h period following admission and both CK-MB and myoglobin concentrations were measured. We compared the performance of single values of both tests. Myoglobin concentration, in the coronary care population studied, proved to be as specific as CK-MB concentration (92–6% in both cases) but with sensitivity of 100% being achieved 1 · 5 h post admission rather than 4 h post admission in the case of CK-MB. On this evidence, measurement of plasma myoglobin could prove useful in the rapid diagnosis of myocardial infarction with consequent effects on optimal Coronary Care utilisation and selection of patients for thrombolytic therapy.


1998 ◽  
Vol 24 (2) ◽  
pp. 187-196 ◽  
Author(s):  
Lung-Chun Lin ◽  
Chau-Chung Wu ◽  
Yi-Lwun Ho ◽  
Chii-Wann Lin ◽  
Wen-Jone Chen ◽  
...  

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