Collision tumor of thyroid: metastatic lung adenocarcinoma plus papillary thyroid carcinoma

2007 ◽  
Vol 28 (3) ◽  
pp. 218-220 ◽  
Author(s):  
Vishad Nabili ◽  
Sathima Natarajan ◽  
Sharon Hirschovitz ◽  
Sunita Bhuta ◽  
Elliot Abemayor
OALib ◽  
2017 ◽  
Vol 04 (12) ◽  
pp. 1-6
Author(s):  
Mofiyinfolu Sokoya ◽  
Carissa M. Thomas ◽  
Marcia Eustaquio

2021 ◽  
Vol 14 (7) ◽  
pp. e242278
Author(s):  
Maria Cecilia Schultze ◽  
Cintia Castro-Correia ◽  
Maria Bom-Sucesso ◽  
Marianne Becker

The most frequent type of thyroid malignancy in children is papillary thyroid carcinoma (PTC), which usually presents as a thyroid nodule, but may also present as a diffuse infiltration with microcalcifications. Herein, we report the case of an uncommon presentation of a PTC in a 7-year-old boy. The child was referred for a goiter with cervical lymphadenopathies. Ultrasonography showed a hypervascularised goiter without microcalcifications but with numerous bilateral cervical nodular formations. A lymph node biopsy revealed metastatic thyroid cancer, hence a total thyroidectomy and complete neck dissection were performed. Histopathology confirmed a PTC. Ablative 131I, 30 mCi was performed 4 months postsurgery. At the end of this treatment, a metastatic lung nodule was identified. Since then, another three ablative 131I treatments have been administered. Thyroid cancers presenting as a diffuse infiltration without microcalcifications are rare. In the presence of lymphadenopathies, thyroid cancer needs to be suspected, even without microcalcifications.


2014 ◽  
Vol 14 (1) ◽  
pp. 18
Author(s):  
Ho Chul Jeong ◽  
Je Ryong Kim ◽  
Byong Hyon Ahn ◽  
Jin Sun Lee ◽  
Eil Sung Chang ◽  
...  

Author(s):  
Joana Ferra ◽  
Cátia Guimarães ◽  
Cristina Matos ◽  
Fernando Nogueira

Synchronous tumours are defined as two or more independent primary neoplasms of different origins diagnosed at the same time in 1 individual. Although rare, its incidence is increasing and the proper diagnosis and staging of each tumour is crucial in defining the patient prognosis and the best therapeutic choice. We present a case of a 56-year-old woman presenting with a lung adenocarcinoma and pulmonary metastases initially diagnosed as stage IV and who was started on a tyrosine kinase inhibitor (erlotinib). In the meantime, she was also diagnosed with papillary thyroid carcinoma and was submitted to complete thyroidectomy. After 6 cycles of erlotinib, thoracic CT showed a decrease in the dimensions of the primary pulmonary tumour, but an increase in the size and number of pulmonary metastases while blood tests showed elevated thyroglobulin. This therefore raised the possibility that the metastases could have originated from the thyroid carcinoma. Anatomo-pathological examination of the lung metastases confirmed this hypothesis. In conclusion, it is important to confirm the origin of metastases in synchronous tumours given this can lead to a re-staging of tumours and a different prognosis, along with other therapeutic options. A multidisciplinary team meeting is crucial to define management and therapeutic approaches for these patients.


2013 ◽  
Vol 5 (2) ◽  
pp. 55-58
Author(s):  
Geeta Lal ◽  
Anuradha R Bhama

ABSTRACT Autoimmune rheumatic diseases, such as polymyositis and dermatomyositis, have been demonstrated to carry a risk of the development of malignancy. Thyroid cancer is a rare occurrence in this setting; however, multiple cases have been reported. We present two cases of papillary thyroid carcinoma associated with dermatomyositis and polymyositis. The first patient is a 64-year-old female found to have papillary thyroid cancer after the diagnosis of polymyositis who underwent thyroid resection. The second patient is a 51-year-old male who was found to have synchronous papillary thyroid cancer and small cell carcinoma of the lung. He did not undergo thyroid resection due to widely metastatic lung cancer. We describe two cases of papillary thyroid cancer associated with autoimmune rheumatic disease. Though it is rare, thyroid cancer should remain in the differential diagnosis of a patient with new onset autoimmune rheumatic disease, as this may alter the eventual management of these patients. How to cite this article Lal G, Bhama AR. Autoimmune Rheumatic Disease (Polymyositis and Dermatomyositis) associated with Papillary Thyroid Carcinoma: Report of Two Cases and Review of the Literature. World J Endoc Surg 2013;5(2):55-58.


Author(s):  
Savita Saharan ◽  
Ranjana Solanki ◽  
Deepak Saharan

<p>Medullary thyroid carcinoma and papillary thyroid carcinoma are two distinct types of thyroid carcinoma having different cellular origin. The simultaneous occurrence of two distinct neoplasms termed “collision tumour” and it is a rare entity. Sometimes the medullary component does not show calcitonin positivity and hence this becomes a very rare entity. Herein we describe a very rare case of simultaneous occurrence of calcitonin negative medullary thyroid carcinoma and papillary thyroid carcinoma.</p>


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