Huge follicular carcinoma originated from struma ovarii in young woman; Extremely rare case

Struma ovarii is a rare variant of the mature ovarian teratoma composed of more than 50% thyroid tissue. Thyroid type carcinoma can occur in 5% of struma ovarii. Given the rarity of this pathology, as well as the different clinical course, approaches to the treatment of this disease are controversial. The proposed approaches to treatment vary from ovarian resection to total hysterectomy with bilateral salpingo-oophorectomy and adjuvant therapy. We present here 6 case reports of thyroid type carcinoma in struma ovarii and outcome of patients treated in our clinic. All patients had pelvic surgery of different extent, followed by thyroidectomy and radioiodine therapy. The incidence of metastasis is 67% (4/6), 2 - intraperitoneal metas-tases, 2 - bone metastases. Among patients with metastases, 2 have reached a complete response, one with a good response continues treatment, one had progression. The follow-up period is 1 to 15 years (median 4 years). One patient with follicular carcinoma died of progression 8 years after diagnosis. The remaining patients are alive.

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A rare case of gonadotroph adenoma in a young woman

Endocrine Abstracts ◽

10.1530/endoabs.75.p05 ◽

2021 ◽

Author(s):

Miriam Veleno ◽

Ettore Maggio ◽

Cesare Morgante ◽

Roberto Novizio ◽

Leo Maria Laura ◽

...

Keyword(s):

Young Woman ◽

Rare Case ◽

Gonadotroph Adenoma

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SKULL METASTASES OF FOLLICULAR CARCINOMA THYROID: A RARE CASE REPORT

10.36106/gjra/3605234 ◽

2021 ◽

pp. 24-25

Author(s):

Smriti Kumari ◽

Manoj Kumar Paswan ◽

Nishat Ahamad

Keyword(s):

Blood Pressure ◽

Heart Rate ◽

Case Report ◽

Body Temperature ◽

Thyroid Gland ◽

Basal Metabolic Rate ◽

Rare Case ◽

Follicular Carcinoma ◽

Rare Case Report ◽

Follicular Carcinoma Thyroid

The thyroid gland, usually located below and anterior to the larynx, consists of two bulky lateral lobes connected by a relatively thin isthmus. The thyroid is divided by thin brous septae into lobules composed of about 20 to 40 evenly dispersed follicles, lined by a cuboidal to low columnar [1] epithelium, and lled with PAS-positive thyroglobulin. The thyroid secretes hormones that control the heart rate, blood pressure, body temperature and basal metabolic rate

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Proliferative struma ovarii: A rare case report

International Journal of Clinicopathological Correlation ◽

10.4103/ijcpc.ijcpc_9_21 ◽

2021 ◽

Vol 5 (2) ◽

pp. 85

Author(s):

GaganKumar Rangari ◽

Shankhanila Mazumdar ◽

Neeraj Dhameja ◽

NishaRani Agrawal

Keyword(s):

Case Report ◽

Rare Case ◽

Struma Ovarii ◽

Rare Case Report

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Multiple Primary Malignancies of Cancer of Ovary and Cervix in A Young Woman: A Rare Case Report

Indian Journal of Gynecologic Oncology ◽

10.1007/s40944-018-0182-0 ◽

2018 ◽

Vol 16 (2) ◽

Author(s):

Sangeeta Pankaj ◽

Anjili Kumari ◽

Syed Nazneen ◽

Jaya Kumari ◽

Vijayanand Choudhary ◽

...

Keyword(s):

Case Report ◽

Young Woman ◽

Rare Case ◽

Multiple Primary Malignancies ◽

Multiple Primary ◽

Rare Case Report

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A Rare Case of Functional Ectopic Hyperthyroidism: Struma Ovarii

World Journal of Endocrine Surgery ◽

10.5005/jp-journals-10002-1194 ◽

2016 ◽

Vol 8 (3) ◽

pp. 212-213

Author(s):

Indu Lata ◽

Deepa Kapoor

Keyword(s):

Rare Case ◽

Histopathological Examination ◽

Thyroid Tissue ◽

Signs And Symptoms ◽

Total Abdominal Hysterectomy ◽

Abdominal Hysterectomy ◽

Cystic Mass ◽

Surgical Removal ◽

Struma Ovarii ◽

Lower Abdomen

ABSTRACT Struma ovarii (SO) is a rare special type of monodermal teratoma of ovary that predominantly consists of thyroid tissue (> 50%). In only 5 to 20% of cases hyperthyroidism is seen due to functional SO. We are reporting here a case of unilateral benign cystic SO in a 50-year-old postmenopausal lady presented with pain and heaviness in lower abdomen without any signs and symptoms of hyperthyroidism. Pelvic ultrasonogram showed right side tubo-ovarian mass and was planned for laparotomy. In preoperative investigation subclinical hyperthyroidism was diagnosed. Abdominal exploration showed cystic mass lesion in right ovary. She underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy. Histopathological examination diagnosed the mass as benign cystic SO. Patient became euthyroid after surgical removal of tumor. How to cite this article Lata I, Kapoor D. A Rare Case of Functional Ectopic Hyperthyroidism: Struma Ovarii. World J Endoc Surg 2016;8(3):212-213.

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A rare case of papillary thyroid carcinoma arising in struma ovarii

Sri Lanka Journal of Obstetrics and Gynaecology ◽

10.4038/sljog.v31i2.1761 ◽

2010 ◽

Vol 31 (2) ◽

pp. 139

Author(s):

MAMM Jayawardane ◽

A Kuluarachchi

Keyword(s):

Papillary Thyroid Carcinoma ◽

Thyroid Carcinoma ◽

Rare Case ◽

Struma Ovarii ◽

Papillary Thyroid

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Malignant Clinical Course of Histologically Benign Ovarian Struma: case report and literature review

10.21203/rs.3.rs-646069/v1 ◽

2021 ◽

Author(s):

Aleksandra Asaturova ◽

A. Magnaeva ◽

A. Tregubova ◽

V. Kometova ◽

E. Karamurzin ◽

...

Keyword(s):

Case Report ◽

Ovarian Tumor ◽

Clinical Course ◽

Mature Teratoma ◽

Thyroid Tissue ◽

Follicular Carcinoma ◽

Struma Ovarii ◽

Diagnostic Challenge ◽

Laboratory Findings ◽

Metastatic Lesions

Abstract BackgroundStruma ovarii is a variant of monodermal teratoma, consisting of morphologically benign, atypical, or frankly malignant thyroid tissue. Morphologic features may or may not correlate with biologic behavior. Albeit this case report is not unique, ovarian tumor developed with peritoneal dissemination and bone metastasis, which is highly unlikely clinical complication. Additionally, we summarized previously cases of struma ovarii with an emphasis on correlation between morphological appearances, clinical course and providing treatment. Case presentationWe present the 38-year-old patient who was hospitalized for ovarian tumor. The diagnostic laparoscopy revealed lesions of peritoneum, sigmoid serosa and omentum and left ovarian mass. We diagnosed left ovarian mature teratoma without struma tissue and metastatic lesions with struma morphology which can be related to her history of left ovarian struma in 2016. Taking into account the metastatic lesions revealed in 2020, the tumor removed in 2016 was assessed as highly differentiated follicular carcinoma arising in struma ovarii. ConclusionsPrediction of biologic behavior of struma ovarii is still to be to diagnostic challenge, therefore multidisciplinary approach including clinical a n d laboratory findings, radiologic details and histopathological features is required. Providing additional data, the present case report contributes to expending the knowledge of these peculiar neoplasms.

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