High-grade mucinous tubular and spindle cell carcinoma: comparative genomic hybridization study

2011 ◽  
Vol 15 (6) ◽  
pp. 472-475 ◽  
Author(s):  
Naoto Kuroda ◽  
Takushi Naroda ◽  
Masato Tamura ◽  
Takahiro Taguchi ◽  
Akira Tominaga ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Comparative Genomic Hybridization ◽  
Spindle Cell ◽  
Spindle Cell Carcinoma ◽  
Comparative Genomic ◽  
High Grade ◽  
Hybridization Study ◽  
Genomic Hybridization

Aggressive high-grade mucinous tubular and spindle cell carcinoma

2009 ◽  
Vol 40 (6) ◽  
pp. 906-907 ◽  
Author(s):  
Stela Bulimbasic ◽  
Danica Ljubanovic ◽  
Radek Sima ◽  
Michal Michal ◽  
Ondrej Hes ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Spindle Cell ◽  
Spindle Cell Carcinoma ◽  
High Grade

scholarly journals Amplification at 9p in Cervical Carcinoma by Comparative Genomic Hybridization

2001 ◽  
Vol 22 (3) ◽  
pp. 159-163 ◽  
Author(s):  
Kowan J. Jee ◽  
Young Tak Kim ◽  
Kyu Rae Kim ◽  
Yan Aalto ◽  
Sakari Knuutila
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Comparative Genomic Hybridization ◽  
Copy Number ◽  
Comparative Genomic ◽  
Malignant Cells ◽  
Genomic Hybridization ◽  
Carcinoma Of Cervix ◽  
Chromosome Arm ◽  
Copy Number Changes

DNA copy number changes were studied by comparative genomic hybridization on 10 tumor specimens of squamous cell carcinoma of cervix obtained from Korean patients. DNA was extracted from paraffin‐embedded sections after removal of non‐malignant cells by microdissection technique. Copy number changes were found in 8/10 tumors. The most frequent changes were chromosome 19 gains (n=6) and losses on chromosomes 4 (n=4), 5 (n=3), and 3p (n=3). A novel finding was amplification in chromosome arm 9p21‐pter in 2 cases. Gains in 1, 3q, 5p, 6p, 8q, 16p, 17, and 20q and losses at 2q, 6q, 8p, 9q, 10p, 11, 13, 16q, and 18q were observed in at least one of the cases.

scholarly journals A case of high-grade mucinous tubular and spindle cell carcinoma

2020 ◽  
Vol 2020 (2) ◽  
Author(s):  
Koujin Miura ◽  
Yasushi Adachi ◽  
Toshiaki Shirahase ◽  
Yoji Nagashima ◽  
Kazuki Suemune ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Poor Prognosis ◽  
Spindle Cell ◽  
Left Kidney ◽  
Spindle Cell Carcinoma ◽  
Low Grade ◽  
High Grade ◽  
Tomography Scan

Abstract Mucinous tubular and spindle cell carcinoma (MTSCC) is a rare renal cell carcinoma that initially presents as low-grade renal cell carcinoma. However, cases of MTSCC with high-grade histology and poor prognosis have been reported. Here, we report a case of MTSCC with high-grade histological features and metastasis. A 77-year-old woman consulted a hospital following frequent and painful micturition. Computed tomography scan revealed a tumor of the left kidney. First, chemotherapy was performed, with no effects. Therefore, nephrectomy was subsequently performed. Histologically, the tumor showed the features of MTSCC with sarcomatoid component. Metastasis of the tumor into the lymph node was also observed. Although adjuvant chemotherapy was performed after nephrectomy, metastasis to the lungs and bone and local recurrence was observed. The patient is still alive 2 years after nephrectomy with metastasis and recurrence of the tumor. High-grade MTSCC shows a relatively poor prognosis, specifically MTSCC with metastasis upon nephrectomy.

A comparative genomic hybridization study in a 46,XX male

2002 ◽  
Vol 78 (1) ◽  
pp. 186-188 ◽  
Author(s):  
M.Angels Rigola ◽  
Marta Carrera ◽  
Isabel Ribas ◽  
Josep Egozcue ◽  
Rosa Miró ◽  
...  
Keyword(s):  
Comparative Genomic Hybridization ◽  
Comparative Genomic ◽  
Hybridization Study ◽  
Genomic Hybridization ◽  
Xx Male
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