Type 2 diabetes and gender differences in liver cancer by considering different confounding factors: a meta-analysis of cohort studies

2016 ◽  
Vol 26 (11) ◽  
pp. 764-772 ◽  
Author(s):  
Yuqin Wang ◽  
Baochan Wang ◽  
Shiyan Yan ◽  
Feng Shen ◽  
Haixia Cao ◽  
...  
2018 ◽  
Vol 42 (5) ◽  
pp. S31 ◽  
Author(s):  
Tauseef Khan ◽  
Mobushra Tayyiba ◽  
Sonia Blanco Mejia ◽  
Fei Au-Yeung ◽  
Cyril Kendall ◽  
...  

2012 ◽  
Vol 15 (7) ◽  
pp. A655
Author(s):  
B. Dipika ◽  
K. Gudala ◽  
K. Undela ◽  
T. Pramil ◽  
A. Bhansali

2014 ◽  
Vol 40 (6) ◽  
pp. 778-785 ◽  
Author(s):  
Yoshimi Fukuoka ◽  
Melinda S. Bender ◽  
JiWon Choi ◽  
Prisila Gonzalez ◽  
Shoshana Arai

Purpose The purpose of this study was to explore gender differences in lay knowledge of type 2 diabetes symptoms among community-dwelling Caucasian, Latino, Filipino, and Korean Americans. Design and Methods A cross-sectional survey was administered to a convenience sample of 904 adults (172 Caucasians, 248 Latinos, 234 Koreans, and 250 Filipinos) without diabetes at community events, community clinics, churches, and online in the San Francisco Bay Area and San Diego from August to December 2013. Participants were asked to describe in their own words signs and/or symptoms of diabetes. A multiple logistic regression analysis was performed to examine the association of lay symptom knowledge with gender after controlling for potential confounding factors. Results Overall, the average age of the sample populations was 44 (SD ±16.1) years, 36% were male, and 58% were married. Increased thirst/dry mouth following increased urinary frequency/color/odor and increased fatigue/lethargy/low energy were the most frequently reported signs and symptoms (19.8%, 15.4%, and 13.6%, respectively). After controlling for known confounding factors, women were 1.6 (95% confidence interval, 1.2-2.3, P = .004) times more likely than men to report at least 1 diabetes symptom. However, this gender difference in knowledge of diabetes signs and symptoms did not significantly differ across Caucasians, Latinos, Filipinos, and Korean Americans ( P = .87). Conclusion The findings underscore the importance of improving public knowledge and awareness of signs and symptoms of diabetes, particularly in men.


2019 ◽  
Vol 13 (4) ◽  
pp. 301-309 ◽  
Author(s):  
Chunmei Guo ◽  
Quanman Li ◽  
Gang Tian ◽  
Yu Liu ◽  
Xizhuo Sun ◽  
...  

2019 ◽  
Vol 122 (04) ◽  
pp. 376-387 ◽  
Author(s):  
J. Zhu ◽  
P. Xun ◽  
J. C. Bae ◽  
J. H. Kim ◽  
D. J. Kim ◽  
...  

AbstractAbnormal Ca homeostasis has been associated with impaired glucose metabolism. However, the epidemiological evidence is controversial. We aimed to assess the association between circulating Ca levels and the risk of type 2 diabetes mellitus (T2DM) or abnormal glucose homeostasis through conducting a systematic review and meta-analysis. Eligible studies were identified by searching electronic database (PubMed, Embase and Google Scholar) and related references withde novoresults from primary studies up to December 2018. A random-effects meta-analysis was performed to estimate the weighted relative risks (RR) and 95 % CI for the associations. The search yielded twenty eligible publications with eight cohort studies identified for the meta-analysis, which included a total of 89 165 participants. Comparing the highest with the lowest category of albumin-adjusted serum Ca, the pooled RR was 1·14 (95 % CI 1·05, 1·24) for T2DM (n51 489). Similarly, serum total Ca was associated with incident T2DM (RR 1·25; 95 % CI 1·10, 1·42) (n64 502). Additionally, the adjusted RR for 1 mg/dl increments in albumin-adjusted serum Ca or serum total Ca levels was 1·16 (95 % CI 1·07, 1·27) and 1·19 (95 % CI 1·11, 1·28), respectively. The observed associations remained with the inclusion of a cohort study with ionised Ca as the exposure. However, data pooled from neither case–control (n4) nor cross-sectional (n8) studies manifested a significant correlation between circulating Ca and glucose homeostasis. In conclusion, accumulated data from the cohort studies suggest that higher circulating Ca levels are associated with an augmented risk of T2DM.


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