scholarly journals 836P Socioeconomic inequalities in treatment and relative survival among patients with diffuse large B-cell lymphoma: A Hong Kong population-based study

2021 ◽  
Vol 32 ◽  
pp. S777
Author(s):  
S.F. Lee ◽  
A.M. Evens ◽  
A.K. Ng ◽  
M.A. Luque-Fernandez
Keyword(s):  
Hong Kong ◽  
B Cell ◽  
Cell Lymphoma ◽  
Relative Survival ◽  
B Cell Lymphoma ◽  
Population Based ◽  
Socioeconomic Inequalities ◽  
Population Based Study ◽  
Large B Cell Lymphoma ◽  
Large B Cell

Socioeconomic Inequalities in Treatment and Relative Survival Among Patients With Diffuse Large B-Cell Lymphoma in Hong Kong

2020 ◽  
Author(s):  
Shing Fung Lee ◽  
Andrew M. Evens ◽  
Andrea K. Ng ◽  
Miguel Angel Luque-Fernandez
Keyword(s):  
Hong Kong ◽  
B Cell ◽  
Cell Lymphoma ◽  
Relative Survival ◽  
B Cell Lymphoma ◽  
Socioeconomic Inequalities ◽  
Large B Cell Lymphoma ◽  
Large B Cell

scholarly journals Factors related to the relative survival of patients with diffuse large B-cell lymphoma in a population-based study in France: does socio-economic status have a role?

Haematologica ◽  
2016 ◽  
Vol 102 (3) ◽  
pp. 584-592 ◽  
Author(s):  
Sandra Le Guyader-Peyrou ◽  
Sébastien Orazio ◽  
Olivier Dejardin ◽  
Marc Maynadié ◽  
Xavier Troussard ◽  
...  
Keyword(s):  
B Cell ◽  
Cell Lymphoma ◽  
Economic Status ◽  
Relative Survival ◽  
B Cell Lymphoma ◽  
Population Based ◽  
Population Based Study ◽  
Socio Economic Status ◽  
Large B Cell Lymphoma ◽  
Large B Cell

Socioeconomic Inequalities in Treatment and Relative Survival Among Patients with Diffuse Large B-Cell Lymphoma: A Hong Kong Population-Based Study

2021 ◽  
Author(s):  
Shing Fung Lee ◽  
Andrew Evens ◽  
Andrea Ng ◽  
Miguel-Angel Luque-Fernandez
Keyword(s):  
Hong Kong ◽  
Excess Mortality ◽  
Cell Lymphoma ◽  
Relative Survival ◽  
B Cell Lymphoma ◽  
Population Based ◽  
Secular Trends ◽  
Low Ses ◽  
Large B Cell Lymphoma ◽  
Large B Cell

Abstract The influence of socioeconomic status (SES) on access to standard chemotherapy and/or monoclonal antibody therapy, and associated secular trends, relative survival, and excess mortality, among diffuse large B-cell lymphoma (DLBCL) patients is not clear. We conducted a Hong Kong population-based cohort study and identified adult patients with histologically diagnosed DLBCL between 2000 and 2018. We examined the association of SES levels with the odds and the secular trends of receipt of chemotherapy and/or rituximab. Additionally, we estimated the long-term relative survival by SES utilizing Hong Kong life tables. Among 4,017 patients with DLBCL, 2,363 (58.8%) patients received both chemotherapy and rituximab and 740 (18.4%) patients received chemotherapy alone, while 1,612 (40.1%) and 914 (22.8%) patients received no rituximab or chemotherapy, respectively. On multivariable analysis, low SES was associated with lesser use of chemotherapy (odd ratio [OR], 0.44; 95% CI 0.34–0.57) and rituximab (OR, 0.41; 95% CI, 0.32–0.52). The socioeconomic disparity for either treatment showed no secular trend of change. Additionally, patients with low SES showed increased excess mortality, with a hazard ratio of 2.34 (95% CI, 1.67–3.28). Improving survival outcomes for patients with DLBCL requires provision of best available medical care and securing access to treatment regardless of patients’ SES.

scholarly journals Treatment intensity and survival in patients with relapsed or refractory diffuse large B-cell lymphoma in Denmark: a real-life population-based study

2019 ◽  
Vol Volume 11 ◽  
pp. 207-216 ◽  
Author(s):  
Bente Arboe ◽  
Maja Halgren Olsen ◽  
Jette Sønderskov Gørløv ◽  
Anne Katrine Duun-Henriksen ◽  
Susanne Oksbjerg Dalton ◽  
...  
Keyword(s):  
B Cell ◽  
Cell Lymphoma ◽  
Real Life ◽  
B Cell Lymphoma ◽  
Population Based ◽  
Treatment Intensity ◽  
Population Based Study ◽  
Large B Cell Lymphoma ◽  
Large B Cell

Comparison of outcomes among patients aged 80 and over and younger patients with diffuse large B-cell lymphoma: a population based study

2013 ◽  
Vol 55 (3) ◽  
pp. 533-537 ◽  
Author(s):  
Cindy Varga ◽  
Christina Holcroft ◽  
Abbas Kezouh ◽  
Serghei Bucatel ◽  
Nathalie Johnson ◽  
...  
Keyword(s):  
B Cell ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Population Based ◽  
80 And Over ◽  
Aged 80 And Over ◽  
Population Based Study ◽  
Younger Patients ◽  
Large B Cell Lymphoma ◽  
Large B Cell

scholarly journals Ratios of T-cell immune effectors and checkpoint molecules as prognostic biomarkers in diffuse large B-cell lymphoma: a population-based study

2015 ◽  
Vol 2 (10) ◽  
pp. e445-e455 ◽  
Author(s):  
Colm Keane ◽  
Frank Vari ◽  
Mark Hertzberg ◽  
Kim-Anh Lê Cao ◽  
Michael R Green ◽  
...  
Keyword(s):  
T Cell ◽  
B Cell ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Population Based ◽  
Prognostic Biomarkers ◽  
Population Based Study ◽  
Large B Cell Lymphoma ◽  
Large B Cell

Disparities In Receipt Of Radiotherapy and Survival By Age, Sex and Ethnicity Among Patients With Localized Diffuse Large B-Cell Lymphoma

Blood ◽  
2013 ◽  
Vol 122 (21) ◽  
pp. 558-558
Author(s):  
Binay K. Shah ◽  
Amir Bista
Keyword(s):  
B Cell ◽  
Cell Lymphoma ◽  
Survival Rates ◽  
Relative Survival ◽  
B Cell Lymphoma ◽  
Population Based ◽  
P Value ◽  
Large B Cell Lymphoma ◽  
To Receive ◽  
Large B Cell

Abstract Background Combination therapy with 3 cycles of chemotherapy followed by involved field radiotherapy has been a standard of care for treatment of localized diffuse large B-cell lymphoma (Miller TP NEJM 1998). This population based study evaluated ethnic disparities in receipt of radiotherapy (RT) and its effect on survival in patients with localized diffuse large B cell lymphoma (DLBCL) in the United States. Methods The Surveillance, Epidemiology, and End Results database was reviewed to identify patients with stage I DLBCL diagnosed between 1998 and 2008. We used unadjusted and adjusted odds ratio (OR) to analyze association of receipt of radiotherapy with age (<60 and 60+ years), sex and ethnicity (White, Black and Others). We calculated relative survival rates for different cohorts using SEER*Stat software. We used cox’s proportional hazard model to investigate the impact of age, sex and ethnicity on survival rates. Results A total of 11763 patients with localized DLBCL as the only primary malignancy were included in the study. Of the cohort, 38.2% received radiotherapy. Receipt of radiotherapy varied significantly by patient ethnicity - whites were more likely to receive RT compared to blacks and others. Similarly, age <60 years and females were more likely to receive radiotherapy compared with older patients and males (Table – 1). The 1- and 5- year relative survival rates for patients receiving RT were higher compared to those who did not receive RT: 88.3±0.5% vs 73.4±0.6%, p-value <0.0001 at 1-year and 77.8±0.8% vs 62.5±0.7%, p-value <0.0001 at 5-years. Among patients who received RT, 1- and 5- year relative survival rates were significantly higher in whites compared to black or other- race patients. Conclusions This population based study showed that only 38.2% of patients with localized DLBCL received radiotherapy. White patients were more likely to receive RT compared to blacks and others. Survival rates are significantly higher for patients who received RT. Disclosures: No relevant conflicts of interest to declare.

scholarly journals Impact of age and socioeconomic status on treatment and survival from aggressive lymphoma: a UK population-based study of diffuse large B-cell lymphoma

2015 ◽  
Vol 39 (6) ◽  
pp. 1103-1112 ◽  
Author(s):  
Alexandra Smith ◽  
Simon Crouch ◽  
Debra Howell ◽  
Cathy Burton ◽  
Russell Patmore ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
B Cell ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Population Based ◽  
Aggressive Lymphoma ◽  
Population Based Study ◽  
Large B Cell Lymphoma ◽  
Large B Cell
Sign in / Sign up

Export Citation Format

Share Document