scholarly journals 1494P Anxiety and depression during the COVID-19 pandemic in newly diagnosed advanced cancer patients

2021 ◽  
Vol 32 ◽  
pp. S1098
Author(s):  
B. Obispo ◽  
R. Hernandez ◽  
P. Cruz ◽  
A. Fernandez Montes ◽  
M. Gil Raga ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Advanced Cancer ◽  
Anxiety And Depression ◽  
Newly Diagnosed ◽  
Advanced Cancer Patients

The ESCAPADE Study: Early supportive care for advanced cancer patients, assessing care delivery and provider engagement.

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. e23142-e23142
Author(s):  
Oren Hannun Levine ◽  
Daryl Bainbridge ◽  
Gregory Russell Pond ◽  
Marissa Slaven ◽  
Sukhbinder K. Dhesy-Thind ◽  
...  
Keyword(s):  
Palliative Care ◽  
Disease Management ◽  
Cancer Patients ◽  
Advanced Cancer ◽  
Healthcare Providers ◽  
Primary Care Providers ◽  
Newly Diagnosed ◽  
Care Providers ◽  
Advanced Cancer Patients ◽  
Gi Cancer

e23142 Background: Advanced cancer patients benefit from early integration of palliative care (EIPC) with usual care. A proposed model of EIPC reserves specialized palliative care (SPC) for complex patients, while primary care providers (PCP) and oncologists oversee basic palliative care (PC). We studied the attitudes among patients and their healthcare providers regarding delivery of EIPC. Methods: A cross-sectional study at a tertiary cancer centre in Ontario. Patients with newly diagnosed incurable gastrointestinal (GI) cancer were surveyed using a study specific instrument for the outcomes of interest: importance of and preferences for accessing support across 8 domains of PC (disease management, physical, psychological, social, spiritual, practical, end of life care, loss and grief). Healthcare providers within the circle of care completed a parallel survey for each recruited patient. Primary analysis involved use of descriptive statistics to summarize survey results and concordance between patient and provider responses. Results: From Oct 2017 - Nov 2018, 67 patients were surveyed (median age 69, 34% female). 90% had an identified medical oncologist, and 19% had SPC. 97% had a PCP, but only 42% listed a PCP as part of the care team. Median time from first oncology assessment for advanced cancer to patient survey completion was 52.5 days. 85 providers responded (oncologist = 59, PCP = 20, SPC = 6; response rate 92%; 1-3 physician responses per patient). Disease management and physical concerns were most important to patients. In these domains, 67% and 81% of patients endorsed receiving care from the preferred provider, but concordance between patient and physician responses regarding most responsible provider was only 58% and 38%. For all other domains, 87 – 100% of patients attributed primary responsibility to self or family rather than any healthcare provider. Conclusions: Respondents did not assign responsibility to physicians early in the disease trajectory for many domains of PC. Our findings suggest that incorporating patient activation and empowerment into EIPC requires further study. PCPs appeared to have limited involvement in PC for newly diagnosed advanced GI cancer patients.

Symptom distress in advanced cancer patients with anxiety and depression in the palliative care setting

2008 ◽  
Vol 17 (5) ◽  
pp. 573-579 ◽  
Author(s):  
Marvin Delgado-Guay ◽  
Henrique A. Parsons ◽  
Zhijun Li ◽  
J. Lynn Palmer ◽  
Eduardo Bruera
Keyword(s):  
Palliative Care ◽  
Cancer Patients ◽  
Advanced Cancer ◽  
Care Setting ◽  
Symptom Distress ◽  
Anxiety And Depression ◽  
Advanced Cancer Patients ◽  
Palliative Care Setting

Use of the scored Patient-Generated Subjective Global Assessment (PG-SGA) to characterize cachexia in newly diagnosed advanced cancer patients

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. 9574-9574
Author(s):  
A. Vigano ◽  
B. Trutschnigg ◽  
J. A. Morais ◽  
P. Chaudhury ◽  
E. Lucar ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Advanced Cancer ◽  
Newly Diagnosed ◽  
Advanced Cancer Patients ◽  
Hand Grip ◽  
Hospitalization Rates ◽  
Hazard Ratios ◽  
Brief Fatigue Inventory

9574 Background: Our objective was to evaluate whether the scored PGSGA questionnaire in advanced cancer patients (ACP) might relate better then weight loss (WL) alone to the nutritional, functional, biological and quality of life features of cachexia (C) and to some complications related to this syndrome. Methods: 214 newly diagnosed ACP with non-small cell lung and gastrointestinal primaries were categorized according to PG-SGA triage intervals of 0–1, 2–8 and ≥9 and also according to WL ≤5% or >5%. Baseline assessments included: hand-grip strenght, body composition by DXA, selective measures of symptom and quality of life (QoL), CBC and differential counts, albumin and CRP. Survival hospitalization rates and data on chemotherapy tolerability were recorded during patient follow-up. Beta coefficients (β), odds ratios (OR), and hazard ratios (HR) were estimated to compare patients with >5% WL to those with ≤5% WL and to compare patients with PGSGA of 0–1 to those with 2–8 and ≥9 scores. All analyses were controlled for gender, age, diagnosis (lung/GI), treatment (radio/chemo), survival (at 8 weeks), and medications. Results: PGSGA was better than the simple recording of WL in defining a population of patients that differed for WBC 109/L(>5% WL β: 0.25 vs. 2–8 PGSGA β: 0.57 and ≥9 PGSGA β: 1.72), CRP mg/L (4.12 vs. 2.16 and 17.49), albumin g/L(-0.63 vs -2.60 and -4.45); weakness 0–10 (1.57 vs.1.56 and 3.32), anorexia 0–10 (2.36 vs. 2.36 and 5.17); Brief Fatigue Inventory 0–90 (17.75 vs. 9.89 and 25.15); McGill QoL 10–0 (-0.95 vs. -0.64 and -2.29); grip strength lbs.(-4.04 vs. -8.82 and -8.06); body fat kg. ( -8.74 vs. -5.94 and -11.72). PGSGA was able to better identify patients with higher rates of both hospitalization (2.6 vs. 1.62 and 9.46) and dose reduction of chemotherapy (1.2 vs. 0.58 and 1.74). Finally, PGSGA was able to better characterize patient survival as compared to WL alone (>5% WL HR: 1.85; 2–8 PGSGA HR: 1.6 and ≥9 PGSGA HR 3.35). Conversely, WL alone was associated with higher probability of a sarcopenia diagnosis by DXA (>5% WL OR: 1.56)Conclusions: Our data support the use of the PGSGA versus the simple recording of WL for identifying C, monitoring its clinical course and predicting possible complications of this syndrome in ACP. No significant financial relationships to disclose.

Relationships between distress and sleep in advanced cancer patients and spouse caregivers.

2018 ◽  
Vol 36 (34_suppl) ◽  
pp. 195-195
Author(s):  
Maija Reblin ◽  
Brian Gonzalez ◽  
Richard E Heyman ◽  
Lee Ellington ◽  
Susan Thomas Vadaparampil
Keyword(s):  
Psychological Distress ◽  
Sleep Disturbance ◽  
Cancer Patients ◽  
Sleep Duration ◽  
Advanced Cancer ◽  
Anxiety And Depression ◽  
Advanced Cancer Patients ◽  
Longitudinal Effects ◽  
Spouse Caregivers ◽  
The Impact

195 Background: Sleep disturbance is a common problem among individuals with advanced cancer. Distress and sleep disturbance are highly interdependent in spouses. Little research has examined dyadic effects of psychological distress on sleep in patient-caregiver spouses, most of whom sleep together. The goal of this study was to determine how anxiety and depression impact one’s own sleep and partner’s sleep in advanced cancer patients and their spouse caregivers. Methods: As part of a larger study, 86 advanced cancer patients and their spouse caregivers completed surveys on demographics and self-reported health, including sleep duration, and the HADS measure of anxiety and depression. A path analysis was conducted to determine the impact of patient and caregiver anxiety and depression on their own and their partner’s sleep. Results: The majority of dyads were white (n = 79) and all were heterosexual. The patient was female in 25 couples. The average age for patients was 67 and 65 for caregivers; couples had been together an average of 35 years. Patients reported sleeping 7.2 hours/night (SD = 1.7) and caregivers reported sleeping 6.72 hours/night (SD = 1.3). Patient and caregiver sleep was significantly correlated (r = .42, p < .01). Controlling for age, sex, and general health, one’s own anxiety was negatively associated with one’s own sleep duration (patient B = -.12, p = .04; caregiver B = -.13, p < .01), but patients’ anxiety was not associated with caregivers’ sleep duration or vice versa. Individuals’ depression was not associated with their own sleep duration, but patient depression was positively associated with caregiver sleep duration (B = .10, p = .05). Conclusions: This is one of the first dyadic explorations of psychological distress and sleep duration in advanced cancer patients and spouse caregivers. The increase in the caregivers’ reported sleep duration associated with patient depression may be an early indicator of caregiver depression. These findings strongly support further research of the dyadic effects of distress on sleep to identify longitudinal effects on holistic sleep outcomes for spouses coping with cancer.

scholarly journals Episodic Breathlessness with and without Background Dyspnea in Advanced Cancer Patients Admitted to an Acute Supportive Care Unit

Cancers ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 2102
Author(s):  
Sebastiano Mercadante ◽  
Claudio Adile ◽  
Patrizia Ferrera ◽  
Giuseppe Bonanno ◽  
Vincenzo Restivo ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Advanced Cancer ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Hospital Anxiety ◽  
Advanced Cancer Patients ◽  
Clinical Appearance ◽  
Factors Influencing ◽  
Numerical Scale ◽  
The Mean

Aim: To characterize episodic breathlessness (EB) in patients with advanced cancer, and to determine factors influencing its clinical appearance. Methods: A consecutive sample of advanced cancer patients admitted to an acute palliative care unit was surveyed. Continuous dyspnea and EB were measured by a numerical scale. The use of drugs used for continuous dyspnea and EB was recorded. Patients were asked about the characteristics of EB (frequency, intensity, duration and triggers). The Multidimensional dyspnea profile (MDP), the Brief dyspnea inventory (BDI), the Athens sleep scale (AIS) and the Hospital Anxiety and Depression Scale (HADS) were also administered. Results: From 439 advanced cancer patients surveyed, 34 and 27 patients had EB, without and with background dyspnea, respectively. The mean intensity and the number of episodes were higher in patients with background dyspnea (p < 0.0005 and p = 0.05, respectively). No differences in duration were observed. Most episodes lasted <10 min. A recognizable cause triggering EB was often found. The presence of both background dyspnea and EB was associated with higher values of MDP and BDI. EB was independently associated with frequency and intensity of background dyspnea (OR = 20.9, 95% CI (Confidence interval) 9.1–48.0; p < 0.0005 and OR = 1.97, 95% CI 1.09–3.58; p = 0.025, respectively) and a lower Karnofsky level (OR = 0.96, 95%CI 0.92–0.98, p = 0.05). Discussion: EB may occur in patients with and without continuous dyspnea, and is often induced by physical and psychological factors. EB intensity is higher in patients with continuous dyspnea. The duration was often so short that the use of drugs, as needed, may be too late, unless administered pre-emptively when the trigger was predictable.

Symptom hyper-expression in advanced cancer patients with anxiety and depression admitted to an acute supportive/palliative care unit

2019 ◽  
Vol 27 (8) ◽  
pp. 3081-3088 ◽  
Author(s):  
Sebastiano Mercadante ◽  
Claudio Adile ◽  
Patrizia Ferrera ◽  
Andrea Cortegiani ◽  
Alessandra Casuccio
Keyword(s):  
Palliative Care ◽  
Cancer Patients ◽  
Advanced Cancer ◽  
Palliative Care Unit ◽  
Anxiety And Depression ◽  
Advanced Cancer Patients

scholarly journals Validation of Hospital Anxiety and Depression Scale as a screening tool for psychological distress in advanced cancer patients undergoing chemotherapy

2011 ◽  
Vol 6 (2) ◽  
pp. 150-157
Author(s):  
Keita Uchino ◽  
Hitoshi Kusaba ◽  
Junji Kishimoto ◽  
Hiroshi Mitsuyasu ◽  
Hiroaki Kawasaki ◽  
...  
Keyword(s):  
Psychological Distress ◽  
Cancer Patients ◽  
Advanced Cancer ◽  
Screening Tool ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Hospital Anxiety ◽  
Advanced Cancer Patients

Assessment of Anxiety and Depression in Advanced Cancer Patients and their Relationship with Quality of Life

2005 ◽  
Vol 14 (8) ◽  
pp. 1825-1833 ◽  
Author(s):  
K. Mystakidou ◽  
E. Tsilika ◽  
E. Parpa ◽  
E. Katsouda ◽  
A. Galanos ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Advanced Cancer ◽  
Anxiety And Depression ◽  
Advanced Cancer Patients
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