Development of a toxicokinetic-toxicodynamic model simulating chronic copper toxicity to the Zebra mussel based on subcellular fractionation

2021 ◽  
pp. 106015
Author(s):  
T.T. Yen Le ◽  
Daniel Grabner ◽  
Milen Nachev ◽  
Míriam R. García ◽  
Eva Balsa-Canto ◽  
...  
1988 ◽  
Vol 27 (04) ◽  
pp. 151-153
Author(s):  
P. Thouvenot ◽  
F. Brunotte ◽  
J. Robert ◽  
L. J. Anghileri

In vitro uptake of 67Ga-citrate and 59Fe-citrate by DS sarcoma cells in the presence of tumor-bearing animal blood plasma showed a dramatic inhibition of both 67Ga and 59Fe uptakes: about ii/io of 67Ga and 1/5o of the 59Fe are taken up by the cells. Subcellular fractionation appears to indicate no specific binding to cell structures, and the difference of binding seems to be related to the transferrin chelation and transmembrane transport differences


1995 ◽  
Vol 30 (2) ◽  
pp. 265-276 ◽  
Author(s):  
Denis Bussières ◽  
Raynald Côté ◽  
Clément Richard ◽  
Édith St-Pierre

Abstract Long-term copper toxicity has been demonstrated in Scenedesmus quadricauda. Upon continuous exposure to copper ions at 250 μg/L, the algae responded by a sharp increase in the synthesis of complexing polypeptides to chelate Cu. Complexing polypeptides gradually decreased, as observed by six sampling tests over 732 h, resembling to a negative exponential curve. This gradual diminution is considered to be a prime mechanism of acclimation or of adaptation to a heavy metal contaminated environment.


BIO-PROTOCOL ◽  
2013 ◽  
Vol 3 (15) ◽  
Author(s):  
Ditte Olsen ◽  
Camilla Gustafsen

1998 ◽  
Vol 12 (4) ◽  
pp. 788-800 ◽  
Author(s):  
Daniel W. Schneider ◽  
Christopher D. Ellis ◽  
Kevin S. Cummings

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